[go: up one dir, main page]

MX2021006986A - Produccion biosintetica de variantes de glucosidos de esteviol. - Google Patents

Produccion biosintetica de variantes de glucosidos de esteviol.

Info

Publication number
MX2021006986A
MX2021006986A MX2021006986A MX2021006986A MX2021006986A MX 2021006986 A MX2021006986 A MX 2021006986A MX 2021006986 A MX2021006986 A MX 2021006986A MX 2021006986 A MX2021006986 A MX 2021006986A MX 2021006986 A MX2021006986 A MX 2021006986A
Authority
MX
Mexico
Prior art keywords
steviol glycosides
variant
biosynthetic production
production
novel steviol
Prior art date
Application number
MX2021006986A
Other languages
English (en)
Inventor
Guohong Mao
Michael Batten
Yang Luo
Oliver Yu
Original Assignee
Conagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conagen Inc filed Critical Conagen Inc
Publication of MX2021006986A publication Critical patent/MX2021006986A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C12N9/1062—Sucrose synthase (2.4.1.13)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Tea And Coffee (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Dairy Products (AREA)

Abstract

La presente invención se refiere a los glucósidos de esteviol novedosos R6-1, R6-2A, R6-2B, R6-4A, R6-4B y R7-2 y a la producción de estos glucósidos de esteviol novedosos, tales como a través de bioconversión enzimática. También se proporciona el uso de estos glucósidos de esteviol novedosos como endulzantes y en productos de consumo de forma oral.
MX2021006986A 2018-12-12 2019-12-12 Produccion biosintetica de variantes de glucosidos de esteviol. MX2021006986A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862778422P 2018-12-12 2018-12-12
PCT/US2019/066090 WO2020123877A1 (en) 2018-12-12 2019-12-12 Biosynthetic production of variant steviol glycosides

Publications (1)

Publication Number Publication Date
MX2021006986A true MX2021006986A (es) 2021-08-16

Family

ID=71075713

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021006986A MX2021006986A (es) 2018-12-12 2019-12-12 Produccion biosintetica de variantes de glucosidos de esteviol.

Country Status (8)

Country Link
US (1) US20210381019A1 (es)
EP (1) EP3894577A4 (es)
JP (1) JP7449586B2 (es)
CN (1) CN113474464B (es)
BR (1) BR112021011419A2 (es)
CA (1) CA3122403A1 (es)
MX (1) MX2021006986A (es)
WO (1) WO2020123877A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016054544A1 (en) * 2014-10-03 2016-04-07 Conagen Inc. Non-caloric sweeteners and methods for synthesizing
AU2020221412A1 (en) * 2019-02-15 2021-09-23 Purecircle Usa Inc. High-purity steviol glycosides
KR20230112673A (ko) * 2020-11-24 2023-07-27 마누스 바이오, 인크. 글리코시드 생성물 생합성 및 회수

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2742142B2 (en) * 2011-08-08 2020-03-25 Evolva SA Recombinant production of steviol glycosides
EP2852296B1 (en) * 2012-05-22 2021-12-15 PureCircle SDN BHD Process for producing a high-purity steviol glycoside
CN110551646B (zh) * 2013-02-06 2024-04-26 埃沃尔瓦公司 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法
EP3063286B1 (en) * 2013-11-01 2018-12-05 Conagen Inc. Recombinant production of steviol glycosides
US9522929B2 (en) * 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
WO2016054544A1 (en) * 2014-10-03 2016-04-07 Conagen Inc. Non-caloric sweeteners and methods for synthesizing
CN108337892B (zh) * 2015-01-30 2022-06-24 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
AU2017285444B2 (en) * 2016-06-17 2021-07-29 Cargill, Incorporated Steviol glycoside compositions for oral ingestion or use
CA3027697C (en) * 2016-06-17 2024-02-20 Cargill, Incorporated Steviol glycoside compositions for oral ingestion or use

Also Published As

Publication number Publication date
WO2020123877A1 (en) 2020-06-18
JP7449586B2 (ja) 2024-03-14
EP3894577A1 (en) 2021-10-20
EP3894577A4 (en) 2023-04-26
US20210381019A1 (en) 2021-12-09
JP2022513480A (ja) 2022-02-08
CN113474464A (zh) 2021-10-01
CN113474464B (zh) 2025-06-10
CA3122403A1 (en) 2020-06-18
BR112021011419A2 (pt) 2021-09-08

Similar Documents

Publication Publication Date Title
MY191735A (en) Production of steviol glycosides in recombinant hosts
SG10201901007PA (en) Production of steviol glycosides in recombinant hosts
MY190212A (en) Production of non-caloric sweeteners using engineered whole-cell catalysts
MX2017004246A (es) Edulcorantes no caloricos y metodos para sintetizar.
MX2019007575A (es) Producción de novedosas preparaciones de beta-lactoglobulina y métodos, usos y productos alimenticios relacionados.
MY182396A (en) Microbial production of steviol glycosides
WO2018102447A3 (en) Food ingredients from stevia rebaudiana
MX367883B (es) Edulcorante no calórico.
EP4477741A3 (en) Oligosaccharide production
MX2011013700A (es) Cepa talaromyces y composiciones de enzimas.
MX2024009298A (es) Composiciones que comprenden rebaudiosido j
MY198001A (en) Production of steviol glycoside in recombinant hosts
MX2024014263A (es) Produccion biosintetica del rebaudiosido d4 de glucosido de esteviol a partir del rebaudiosido e
MX2021006986A (es) Produccion biosintetica de variantes de glucosidos de esteviol.
MX2019004368A (es) Produccion biosintetica de glicosidos de esteviol y procesos de los mismos.
SG11201808405TA (en) Stevia-containing beverage
MY182924A (en) Enzyme compositions and uses thereof
BR112018011611A2 (pt) produção de glicosídeos de esteviol em hospedeiros recombinantes
MY204670A (en) Hydrolysis of steviol glycosides by beta-glucosidase
MX2019004534A (es) Glicosidos de diterpénicos aislados a partir de stevia, composiciones y métodos.
EP4505880A3 (en) Stevia extracts
MX2017014890A (es) Metodos de produccion de acetolactato-descarboxilasa (aldc).
MX2023005754A (es) Proceso para la preparacion de productos alimenticios a base de cereal tratados termicamente.
IN2014CH03785A (es)