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MX2020002726A - Polisulfato de pentosan y metodo para producir polisulfato de pentosan. - Google Patents

Polisulfato de pentosan y metodo para producir polisulfato de pentosan.

Info

Publication number
MX2020002726A
MX2020002726A MX2020002726A MX2020002726A MX2020002726A MX 2020002726 A MX2020002726 A MX 2020002726A MX 2020002726 A MX2020002726 A MX 2020002726A MX 2020002726 A MX2020002726 A MX 2020002726A MX 2020002726 A MX2020002726 A MX 2020002726A
Authority
MX
Mexico
Prior art keywords
sub
pentosan polysulfate
pentosan
hydrogen atom
producing
Prior art date
Application number
MX2020002726A
Other languages
English (en)
Inventor
Kotaro Ishikawa
Takuro Kashiwamura
Takuya Kato
Toru Koga
Suguru Ishikawa
Original Assignee
Oji Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oji Holdings Corp filed Critical Oji Holdings Corp
Publication of MX2020002726A publication Critical patent/MX2020002726A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Sustainable Development (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invención proporciona un polisulfato de pentosán que tiene un contenido de ácido urónico de 0.0% en masa a 6.0% en masa, preferiblemente un polisulfato de pentosán que tiene una estructura representada por la Fórmula I: (ver Fórmula) donde cada R representa un átomo de hidrógeno, -COCH3 o -SO3X y al menos un R representa - SO3X, donde X representa un átomo de hidrógeno o un metal monovalente o divalente y n representa un número entero de 1 o más y 30 o menos; una sal farmacéuticamente aceptable del mismo; o un solvato farmacéuticamente aceptable del polisulfato de pentosán o de una sal farmacéuticamente aceptable del mismo. La presente invención proporciona además un método para producir polisulfato de pentosán, el método comprende los pasos de despolimerizar una materia prima derivada de plantas para obtener un xilooligosacárido neutro y sulfatar el xilooligosacárido neutro, en este orden.
MX2020002726A 2017-09-12 2018-09-11 Polisulfato de pentosan y metodo para producir polisulfato de pentosan. MX2020002726A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017175133 2017-09-12
PCT/JP2018/033535 WO2019054344A1 (ja) 2017-09-12 2018-09-11 ポリ硫酸ペントサン及びポリ硫酸ペントサンの製造方法

Publications (1)

Publication Number Publication Date
MX2020002726A true MX2020002726A (es) 2020-07-20

Family

ID=65722707

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020002726A MX2020002726A (es) 2017-09-12 2018-09-11 Polisulfato de pentosan y metodo para producir polisulfato de pentosan.

Country Status (16)

Country Link
US (1) US11390693B2 (es)
EP (1) EP3683242B1 (es)
JP (2) JP7167039B2 (es)
KR (1) KR102678054B1 (es)
CN (1) CN111065655B (es)
AU (1) AU2018333249B2 (es)
BR (1) BR112020004787A2 (es)
CA (1) CA3075485A1 (es)
FI (1) FI3683242T3 (es)
HU (1) HUE069698T2 (es)
MX (1) MX2020002726A (es)
PH (1) PH12020500458A1 (es)
PL (1) PL3683242T3 (es)
PT (1) PT3683242T (es)
SG (1) SG11202002250VA (es)
WO (1) WO2019054344A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6662503B2 (ja) * 2017-12-20 2020-03-11 王子ホールディングス株式会社 ポリ硫酸ペントサン及びポリ硫酸ペントサンを含む医薬
JP6935960B2 (ja) * 2018-08-20 2021-09-15 株式会社レクメド 新規ポリ硫酸ペントサンナトリウム製剤
CN116284503B (zh) * 2023-03-11 2025-05-16 苏州融析生物科技有限公司 一种木聚糖及其制备方法与应用

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Also Published As

Publication number Publication date
US20200270372A1 (en) 2020-08-27
BR112020004787A2 (pt) 2020-09-24
CN111065655B (zh) 2022-06-14
WO2019054344A1 (ja) 2019-03-21
US11390693B2 (en) 2022-07-19
CA3075485A1 (en) 2019-03-21
JPWO2019054344A1 (ja) 2020-10-15
AU2018333249A1 (en) 2020-04-02
AU2018333249B2 (en) 2023-03-02
HUE069698T2 (hu) 2025-04-28
CN111065655A (zh) 2020-04-24
PH12020500458A1 (en) 2020-12-07
FI3683242T3 (fi) 2025-01-15
PT3683242T (pt) 2024-11-21
JP7167039B2 (ja) 2022-11-08
KR102678054B1 (ko) 2024-06-24
EP3683242A1 (en) 2020-07-22
EP3683242B1 (en) 2024-10-30
PL3683242T3 (pl) 2025-03-03
JP2022180509A (ja) 2022-12-06
KR20200051688A (ko) 2020-05-13
EP3683242A4 (en) 2021-11-03
SG11202002250VA (en) 2020-04-29

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