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MX2020000898A - Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio. - Google Patents

Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio.

Info

Publication number
MX2020000898A
MX2020000898A MX2020000898A MX2020000898A MX2020000898A MX 2020000898 A MX2020000898 A MX 2020000898A MX 2020000898 A MX2020000898 A MX 2020000898A MX 2020000898 A MX2020000898 A MX 2020000898A MX 2020000898 A MX2020000898 A MX 2020000898A
Authority
MX
Mexico
Prior art keywords
nerve
sup
solution
fluid
creating
Prior art date
Application number
MX2020000898A
Other languages
English (en)
Inventor
David M Jackson
Richard Trevino
Jordan A Hoffman
Original Assignee
Neuraptive Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuraptive Therapeutics Inc filed Critical Neuraptive Therapeutics Inc
Publication of MX2020000898A publication Critical patent/MX2020000898A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
    • A61B17/1128—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis of nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0208—Subcutaneous access sites for injecting or removing fluids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00234—Surgical instruments, devices or methods for minimally invasive surgery
    • A61B2017/00345—Micromachines, nanomachines, microsystems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00893—Material properties pharmaceutically effective
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
    • A61B2017/1132—End-to-end connections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un nervio cortado puede ser unido de nuevo quirúrgicamente y los axones cortados fusionados vía administración secuencial de soluciones. Las soluciones pueden incluir una solución cebadora que comprende azul de metileno en una solución salina libre de Ca2+, una solución de fusión que comprende aproximadamente 50% (peso/peso) de PEG y una solución de sellado que comprende solución salina que contiene Ca2+. La solución de fusión de PEG puede ser aplicada en un dispositivo de tratamiento de nervios configurado para aislar el segmento dañado del nervio. El dispositivo puede incluir una cámara de contención para crear un campo de contención de fluido alrededor de la anastomosis. El dispositivo puede incluir ranuras, muescas y/o aberturas en paredes laterales opuestas del dispositivo, diseñadas para recibir el nervio. El dispositivo puede tener una configuración de baño abierto o puede incluir cuerpos superior e inferior separables para crear una configuración de baño cerrado. El dispositivo puede incluir uno o más orificios de fluido en comunicación fluídica con la cámara de contención para introducir o remover fluido.
MX2020000898A 2017-07-26 2018-07-24 Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio. MX2020000898A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762537388P 2017-07-26 2017-07-26
PCT/US2018/043549 WO2019023274A1 (en) 2017-07-26 2018-07-24 DEVICE AND METHOD FOR CREATING A LIQUID CONTAINMENT FIELD FOR ADMINISTERING THERAPEUTIC AGENTS AT A NERVE

Publications (1)

Publication Number Publication Date
MX2020000898A true MX2020000898A (es) 2020-10-14

Family

ID=65041375

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020000898A MX2020000898A (es) 2017-07-26 2018-07-24 Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio.
MX2024004159A MX2024004159A (es) 2017-07-26 2020-01-23 Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2024004159A MX2024004159A (es) 2017-07-26 2020-01-23 Dispositivo y metodo para crear un campo de contencion de fluido aislado para la administracion de agentes terapeuticos a un nervio.

Country Status (10)

Country Link
US (2) US11633188B2 (es)
EP (2) EP4378413A3 (es)
JP (3) JP7225202B2 (es)
KR (1) KR102653455B1 (es)
CN (1) CN111629691A (es)
AU (2) AU2018308115B2 (es)
CA (1) CA3070872A1 (es)
ES (1) ES2984412T3 (es)
MX (2) MX2020000898A (es)
WO (1) WO2019023274A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020206208A1 (en) * 2019-04-03 2020-10-08 Musc Foundation For Research Development Nerve holder device
NL2028041B1 (en) * 2021-04-22 2022-11-02 G C W De Ruiter Holding B V Implantable neuroma formation preventing devices
WO2024141155A1 (en) * 2022-12-27 2024-07-04 Tissium S.A. Nerve conduit system

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Also Published As

Publication number Publication date
JP2024147559A (ja) 2024-10-16
JP2020528801A (ja) 2020-10-01
RU2020103353A (ru) 2021-08-26
EP3658072B1 (en) 2024-03-13
CN111629691A (zh) 2020-09-04
KR20200128377A (ko) 2020-11-12
EP3658072A4 (en) 2021-04-21
EP3658072A1 (en) 2020-06-03
US20230225733A1 (en) 2023-07-20
JP7225202B2 (ja) 2023-02-20
EP4378413A2 (en) 2024-06-05
AU2018308115B2 (en) 2023-12-14
WO2019023274A1 (en) 2019-01-31
AU2024201594A1 (en) 2024-03-28
AU2018308115A1 (en) 2020-02-13
MX2024004159A (es) 2024-04-23
CA3070872A1 (en) 2019-01-31
US11633188B2 (en) 2023-04-25
ES2984412T3 (es) 2024-10-29
EP4378413A3 (en) 2024-08-07
KR102653455B1 (ko) 2024-04-02
EP3658072C0 (en) 2024-03-13
JP7508612B2 (ja) 2024-07-01
RU2020103353A3 (es) 2022-01-27
US20210121181A1 (en) 2021-04-29
JP2023065414A (ja) 2023-05-12

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