MX2019011173A - Compuesto que contiene silicio para la resistencia a la infeccion por el virus de la hepatitis c. - Google Patents
Compuesto que contiene silicio para la resistencia a la infeccion por el virus de la hepatitis c.Info
- Publication number
- MX2019011173A MX2019011173A MX2019011173A MX2019011173A MX2019011173A MX 2019011173 A MX2019011173 A MX 2019011173A MX 2019011173 A MX2019011173 A MX 2019011173A MX 2019011173 A MX2019011173 A MX 2019011173A MX 2019011173 A MX2019011173 A MX 2019011173A
- Authority
- MX
- Mexico
- Prior art keywords
- hepatitis
- virus infection
- silicon
- resistance
- containing compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0816—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring comprising Si as a ring atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención proporciona un compuesto que contiene silicio para la resistencia a la infección por virus de la hepatitis c y, en particular, proporciona un compuesto representado por la fórmula I, o una sal farmacéuticamente aceptable, o un tautómero, o un estereoisómero, o un compuesto deuterado del mismo y una mezcla entre ellos, un proceso para la preparación de este, y una composición farmacéutica que comprende el mismo. La presente solicitud también proporciona un uso del compuesto, o una sal farmacéuticamente aceptable, o un tautómero, o un estereoisómero, o un compuesto deuterado del mismo y una mezcla entre ellos, y una composición farmacéutica que comprende el mismo en el tratamiento de la infección por virus de la hepatitis c.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710172925 | 2017-03-22 | ||
| CN201710845367 | 2017-09-19 | ||
| PCT/CN2018/079965 WO2018171660A1 (zh) | 2017-03-22 | 2018-03-22 | 用于抗丙型肝炎病毒感染的含硅化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019011173A true MX2019011173A (es) | 2020-01-09 |
Family
ID=63585044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019011173A MX2019011173A (es) | 2017-03-22 | 2018-03-22 | Compuesto que contiene silicio para la resistencia a la infeccion por el virus de la hepatitis c. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10766912B2 (es) |
| EP (1) | EP3604295A4 (es) |
| JP (1) | JP2020512331A (es) |
| CN (1) | CN110382487B (es) |
| BR (1) | BR112019019724A2 (es) |
| MX (1) | MX2019011173A (es) |
| WO (1) | WO2018171660A1 (es) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8329159B2 (en) | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN101558059B (zh) | 2006-08-11 | 2014-12-03 | 百时美施贵宝公司 | 丙型肝炎病毒抑制剂 |
| ES2565536T3 (es) | 2009-06-11 | 2016-04-05 | Abbvie Bahamas Ltd. | Heterociclos trisustituidos como inhibidores de la replicación del virus de la Hepatitis C VHC |
| US8937150B2 (en) * | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| PE20130062A1 (es) * | 2010-03-09 | 2013-02-28 | Merck Sharp & Dohme | Compuestos de sililo triciclicos fusionados para el tratamiento de enfermedades virales |
| JP6162704B2 (ja) * | 2011-10-11 | 2017-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | オキサゾリジノン誘導体のシラアナログ及びその合成 |
| US8927749B2 (en) * | 2013-03-07 | 2015-01-06 | Universal Display Corporation | Organic electroluminescent materials and devices |
| WO2016095814A1 (en) * | 2014-12-16 | 2016-06-23 | Sunshine Lake Pharma Co., Ltd. | Bridged ring compounds as hepatitis c virus inhibitors and preparation thereof |
-
2018
- 2018-03-22 CN CN201880015765.9A patent/CN110382487B/zh active Active
- 2018-03-22 MX MX2019011173A patent/MX2019011173A/es unknown
- 2018-03-22 US US16/494,604 patent/US10766912B2/en not_active Expired - Fee Related
- 2018-03-22 JP JP2019552128A patent/JP2020512331A/ja active Pending
- 2018-03-22 EP EP18771081.9A patent/EP3604295A4/en not_active Withdrawn
- 2018-03-22 BR BR112019019724A patent/BR112019019724A2/pt not_active Application Discontinuation
- 2018-03-22 WO PCT/CN2018/079965 patent/WO2018171660A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN110382487A (zh) | 2019-10-25 |
| BR112019019724A2 (pt) | 2020-04-14 |
| EP3604295A1 (en) | 2020-02-05 |
| US20200017532A1 (en) | 2020-01-16 |
| JP2020512331A (ja) | 2020-04-23 |
| US10766912B2 (en) | 2020-09-08 |
| CN110382487B (zh) | 2021-04-02 |
| WO2018171660A1 (zh) | 2018-09-27 |
| EP3604295A4 (en) | 2020-12-16 |
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