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MX2019006745A - Metodo para el tratamiento de la epilepsia. - Google Patents

Metodo para el tratamiento de la epilepsia.

Info

Publication number
MX2019006745A
MX2019006745A MX2019006745A MX2019006745A MX2019006745A MX 2019006745 A MX2019006745 A MX 2019006745A MX 2019006745 A MX2019006745 A MX 2019006745A MX 2019006745 A MX2019006745 A MX 2019006745A MX 2019006745 A MX2019006745 A MX 2019006745A
Authority
MX
Mexico
Prior art keywords
treating epilepsy
epilepsy
alprazolam
seizures
inhaled
Prior art date
Application number
MX2019006745A
Other languages
English (en)
Other versions
MX393985B (es
Inventor
Cassella James
GONG Lily
S Kamemoto Edwin
Original Assignee
Alexza Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexza Pharmaceuticals Inc filed Critical Alexza Pharmaceuticals Inc
Publication of MX2019006745A publication Critical patent/MX2019006745A/es
Publication of MX393985B publication Critical patent/MX393985B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Dispersion Chemistry (AREA)

Abstract

Alprazolam formulado como un aerosol de condensación inhalado y un método para tratar la epilepsia y/o las convulsiones.
MX2019006745A 2016-12-09 2017-12-08 Metodo para el tratamiento de la epilepsia MX393985B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662432353P 2016-12-09 2016-12-09
US201762485281P 2017-04-13 2017-04-13
PCT/US2017/065347 WO2018107045A1 (en) 2016-12-09 2017-12-08 Method of treating epilepsy

Publications (2)

Publication Number Publication Date
MX2019006745A true MX2019006745A (es) 2019-10-14
MX393985B MX393985B (es) 2025-03-24

Family

ID=62492165

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019006745A MX393985B (es) 2016-12-09 2017-12-08 Metodo para el tratamiento de la epilepsia
MX2022008775A MX2022008775A (es) 2016-12-09 2019-06-07 Metodo para el tratamiento de la epilepsia.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022008775A MX2022008775A (es) 2016-12-09 2019-06-07 Metodo para el tratamiento de la epilepsia.

Country Status (21)

Country Link
US (4) US11241383B2 (es)
EP (2) EP4272827A3 (es)
JP (4) JP7379154B2 (es)
KR (4) KR102871666B1 (es)
CN (2) CN116172985A (es)
AU (3) AU2017370747A1 (es)
CA (1) CA3046385C (es)
DK (1) DK3551189T3 (es)
ES (1) ES2968097T3 (es)
FI (1) FI3551189T3 (es)
HR (1) HRP20240106T1 (es)
HU (1) HUE064864T2 (es)
IL (1) IL267199A (es)
LT (1) LT3551189T (es)
MX (2) MX393985B (es)
PL (1) PL3551189T3 (es)
PT (1) PT3551189T (es)
RS (1) RS65112B1 (es)
SI (1) SI3551189T1 (es)
SM (1) SMT202400023T1 (es)
WO (1) WO2018107045A1 (es)

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US11241383B2 (en) 2016-12-09 2022-02-08 Alexza Pharmaceuticals, Inc. Method of treating epilepsy
US11642473B2 (en) 2007-03-09 2023-05-09 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

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CN118831072B (zh) * 2024-09-24 2024-11-22 四川大学华西医院 一种阿普唑仑鼻腔吸入制剂及其制备方法
CN119139318B (zh) * 2024-09-24 2025-04-01 四川大学华西医院 一种阿普唑仑凝胶微粒在制备治疗癫痫持续状态的药物中的用途

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11642473B2 (en) 2007-03-09 2023-05-09 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US12138383B2 (en) 2007-03-09 2024-11-12 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US11241383B2 (en) 2016-12-09 2022-02-08 Alexza Pharmaceuticals, Inc. Method of treating epilepsy
US11717479B2 (en) 2016-12-09 2023-08-08 Alexza Pharmaceuticals, Inc. Method of treating epilepsy
US12133915B2 (en) 2016-12-09 2024-11-05 Alexza Pharmaceuticals, Inc. Method of treating epilepsy
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device
US12214119B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Also Published As

Publication number Publication date
CA3046385A1 (en) 2018-06-14
HUE064864T2 (hu) 2024-04-28
US12133915B2 (en) 2024-11-05
FI3551189T3 (fi) 2024-01-31
KR20190104531A (ko) 2019-09-10
US11241383B2 (en) 2022-02-08
JP2023118696A (ja) 2023-08-25
US11717479B2 (en) 2023-08-08
US20190307680A1 (en) 2019-10-10
CN116172985A (zh) 2023-05-30
MX2022008775A (es) 2022-07-27
EP4272827A2 (en) 2023-11-08
EP3551189B1 (en) 2023-11-01
JP2020500911A (ja) 2020-01-16
KR20250048151A (ko) 2025-04-07
KR20230066655A (ko) 2023-05-16
SMT202400023T1 (it) 2024-03-13
JP2025116139A (ja) 2025-08-07
HRP20240106T1 (hr) 2024-04-12
EP4272827A3 (en) 2024-01-24
JP7379154B2 (ja) 2023-11-14
SI3551189T1 (sl) 2024-03-29
EP3551189A1 (en) 2019-10-16
US20210244661A1 (en) 2021-08-12
JP7690514B2 (ja) 2025-06-10
AU2022287583B2 (en) 2025-02-06
JP2021154135A (ja) 2021-10-07
US20220241191A1 (en) 2022-08-04
EP3551189A4 (en) 2020-07-22
WO2018107045A1 (en) 2018-06-14
PL3551189T3 (pl) 2024-04-22
AU2021202621A1 (en) 2021-05-27
CA3046385C (en) 2023-12-19
KR20220164620A (ko) 2022-12-13
MX393985B (es) 2025-03-24
DK3551189T3 (da) 2024-01-29
US20250032407A1 (en) 2025-01-30
RS65112B1 (sr) 2024-02-29
KR102871666B1 (ko) 2025-10-15
ES2968097T3 (es) 2024-05-07
JP7376532B2 (ja) 2023-11-08
PT3551189T (pt) 2024-01-22
AU2021202621B2 (en) 2022-09-15
IL267199A (en) 2019-08-29
AU2022287583A1 (en) 2023-02-02
LT3551189T (lt) 2024-02-12
AU2017370747A1 (en) 2019-06-27
CN110267662A (zh) 2019-09-20

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