[go: up one dir, main page]

MX2019005239A - Sistemas y metodo para secuestrar sustancias en liquidos a granel. - Google Patents

Sistemas y metodo para secuestrar sustancias en liquidos a granel.

Info

Publication number
MX2019005239A
MX2019005239A MX2019005239A MX2019005239A MX2019005239A MX 2019005239 A MX2019005239 A MX 2019005239A MX 2019005239 A MX2019005239 A MX 2019005239A MX 2019005239 A MX2019005239 A MX 2019005239A MX 2019005239 A MX2019005239 A MX 2019005239A
Authority
MX
Mexico
Prior art keywords
vertex
interest
analyte
systems
magnetic
Prior art date
Application number
MX2019005239A
Other languages
English (en)
Inventor
Feistel Christopher
Original Assignee
Wavesense Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wavesense Inc filed Critical Wavesense Inc
Publication of MX2019005239A publication Critical patent/MX2019005239A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/30—Combinations with other devices, not otherwise provided for
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Se describen los sistemas y métodos para detectar y secuestrar analitos objetivo en una muestra fluida. El sistema comprende un depósito de especímenes a granel para recibir una muestra líquida, junto con materiales paramagnéticos operativos para unirse selectivamente al analito objetivo de interés. Un vértice está interconectado con el depósito de muestra a granel para definir un montaje de cámara de espécimen en el que se despliega una cámara magnética alrededor de la porción de vértice de la misma y operativo para secuestrar las partículas magnéticas, así como cualquier analito de interés enlazado al mismo, dentro del interior del vértice. Una vez que se deja suficiente tiempo para mezclar y permitir que la cápsula magnética retenga suficientemente las partículas magnéticas dentro del vértice, el vértice se desconecta del depósito de la muestra y los materiales paramagnéticos retenidos en el mismo se analizan para determinar la presencia del analito de interés.
MX2019005239A 2016-11-07 2017-11-06 Sistemas y metodo para secuestrar sustancias en liquidos a granel. MX2019005239A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/345,271 US10329554B2 (en) 2016-11-07 2016-11-07 System and method for sequestering substances in bulk liquids
PCT/US2017/060224 WO2018085781A2 (en) 2016-11-07 2017-11-06 Systems and method for sequestering substances in bulk liquids

Publications (1)

Publication Number Publication Date
MX2019005239A true MX2019005239A (es) 2020-01-15

Family

ID=62065595

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019005239A MX2019005239A (es) 2016-11-07 2017-11-06 Sistemas y metodo para secuestrar sustancias en liquidos a granel.

Country Status (12)

Country Link
US (2) US10329554B2 (es)
EP (1) EP3535058B1 (es)
JP (1) JP2020500505A (es)
KR (1) KR102239349B1 (es)
CN (1) CN110167674B (es)
AU (1) AU2017355635B2 (es)
CA (1) CA3042426C (es)
DK (1) DK3535058T3 (es)
ES (1) ES2895423T3 (es)
MX (1) MX2019005239A (es)
PL (1) PL3535058T3 (es)
WO (1) WO2018085781A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD886320S1 (en) * 2019-04-29 2020-06-02 Wavesense, Inc. Fluid sequestration apparatus
USD890362S1 (en) * 2019-05-07 2020-07-14 Wavesense, Inc. Annular magnet housing
JP2020204507A (ja) * 2019-06-17 2020-12-24 東芝テック株式会社 検出装置及び検出方法
US11545490B2 (en) 2019-12-17 2023-01-03 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor structure and method for forming the same
CN116422389B (zh) * 2023-04-03 2024-11-08 宁波玄流智造有限公司 一种微流控芯片及其在制备脂质纳米颗粒中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8951191A (en) * 1990-10-29 1992-05-26 Dekalb Plant Genetics Isolation of biological materials using magnetic particles
US5186827A (en) * 1991-03-25 1993-02-16 Immunicon Corporation Apparatus for magnetic separation featuring external magnetic means
CA2105962A1 (en) * 1992-09-18 1994-03-19 Margaret Patricia Raybuck Device and method for affinity separation
US5648223A (en) * 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
EP0963554B1 (de) 1997-01-30 2002-10-23 MERCK PATENT GmbH Verfahren zur immunologischen bestimmung eines analyten
US7348182B2 (en) 2000-10-03 2008-03-25 Mirari Biosciences, Inc. Directed microwave chemistry
US20060223178A1 (en) 2005-04-05 2006-10-05 Tom Barber Devices and methods for magnetic enrichment of cells and other particles
EP1969337A4 (en) 2005-12-23 2010-01-27 Perkinelmer Las Inc MULTIPLEX ANALYSIS CARRIED OUT BY MEANS OF MAGNETIC PARTICLES AND NON-MAGNETIC PARTICLES
GB0616508D0 (en) 2006-08-18 2006-09-27 Iti Scotland Ltd Analyte manipulation and detection
WO2008133726A2 (en) * 2006-11-14 2008-11-06 The Cleveland Clinic Foundation Magnetic cell separation
GB0701641D0 (en) 2007-01-29 2007-03-07 Iti Scotland Ltd Analyte manipulation and detection
RU2010127266A (ru) * 2007-12-05 2012-01-10 Зиомикс, Инк. (Us) Набор для анализа клеток и способ
EP2271919A1 (en) * 2008-04-16 2011-01-12 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
US20120132593A1 (en) 2010-11-30 2012-05-31 General Electric Company Systems and methods for magnetic separation of biological materials
US20120270331A1 (en) 2011-04-20 2012-10-25 Achal Singh Achrol Microfluidic system and method for automated processing of particles from biological fluid
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
JP2014083041A (ja) * 2012-10-26 2014-05-12 Seiko Epson Corp 核酸抽出用装置
US9128017B2 (en) * 2013-03-19 2015-09-08 Rarecyte, Inc. Device, systems and methods for analyzing a target analyte
US9194142B2 (en) 2013-06-04 2015-11-24 Glenmore Industries LLC Modular wall system for exhibition booths
US20150024376A1 (en) * 2013-07-19 2015-01-22 Battelle Memorial Institute Trap and flow system and process for capture of target analytes
JP6525341B2 (ja) 2013-09-09 2019-06-05 ラボ − オン − ア − ビード エービー 磁気分離のための新規な方法及びシステム

Also Published As

Publication number Publication date
US20190169599A1 (en) 2019-06-06
PL3535058T3 (pl) 2021-12-27
EP3535058A2 (en) 2019-09-11
KR102239349B1 (ko) 2021-04-12
CA3042426A1 (en) 2018-05-11
US10927366B2 (en) 2021-02-23
ES2895423T3 (es) 2022-02-21
US20180127741A1 (en) 2018-05-10
JP2020500505A (ja) 2020-01-16
AU2017355635B2 (en) 2022-04-21
US10329554B2 (en) 2019-06-25
WO2018085781A3 (en) 2018-06-14
CN110167674B (zh) 2021-03-12
CA3042426C (en) 2022-11-01
WO2018085781A2 (en) 2018-05-11
EP3535058A4 (en) 2020-08-05
AU2017355635A1 (en) 2019-05-23
CN110167674A (zh) 2019-08-23
EP3535058B1 (en) 2021-07-21
DK3535058T3 (da) 2021-09-20
KR20190083353A (ko) 2019-07-11

Similar Documents

Publication Publication Date Title
MX2019005239A (es) Sistemas y metodo para secuestrar sustancias en liquidos a granel.
AU2022200683A8 (en) Microfluidic devices having isolation pens and methods of testing biological micro-objects with same
MX2016010413A (es) Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.
WO2013122646A3 (en) Systems and methods for analyte detection
NZ728582A (en) Instrument for analyzing biological samples and reagents
WO2018081617A3 (en) Substance preparation evaluation system
CY1126069T1 (el) Προσδιορισμος για αντισωματα ιου jc
MX2017003454A (es) Sistemas y metodos para la integracion de la recoleccion de microfluido lagrimal y el analisis por flujo lateral de analitos de interes.
WO2011091037A3 (en) Rapid pathogen diagnostic device and method
WO2017090043A9 (en) Assay device
WO2012177940A3 (en) Microfluidic devices and methods for separating and detecting constituents in a fluid sample
WO2010151705A3 (en) Capture and elution of bio-analytes via beads that are used to disrupt specimens
MX2009004460A (es) Inmunoensayo de analitos en muestras que contienen anticuerpos anti-analito endogenos.
WO2012138420A3 (en) Systems and methods for harvesting target particles of a suspension
WO2010123594A3 (en) Device for filtration of fluids there through and accompanying method
WO2012122458A3 (en) A cartridge based system and method for detecting an analyte in a sample
MX2015014479A (es) Dispositivo de transferencia de muestras de fluidos biologicos y sistema de separacion y analisis de fluidos biologicos.
MX2019011081A (es) Sistema de liberacion de indicadores para la deteccion de un analito en un producto alimenticio, tiras de prueba para este proposito y metodo de analisis.
WO2013186672A3 (en) Optical detection system for liquid samples
JP2016211886A5 (ja) 被検物質の検出方法および検体分析装置
MX2015014473A (es) Dispositivo de separacion de fluido biologico y sistema de separacion y analisis de fluido biologico.
WO2005124345A3 (en) Method of determining the presence and/or concentration of substances of interest in fluids
MX2015014478A (es) Dispositivo de transferencia de fluidos biologicos y sistema de muestreo de fluidos biologicos.
PL413910A1 (pl) Insert oraz sposób rozdziału płynów z wykorzystaniem gradientu gęstości
JP2017530366A5 (es)