MX2018001989A - Formulaciones farmaceuticas. - Google Patents
Formulaciones farmaceuticas.Info
- Publication number
- MX2018001989A MX2018001989A MX2018001989A MX2018001989A MX2018001989A MX 2018001989 A MX2018001989 A MX 2018001989A MX 2018001989 A MX2018001989 A MX 2018001989A MX 2018001989 A MX2018001989 A MX 2018001989A MX 2018001989 A MX2018001989 A MX 2018001989A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical formulations
- ascomycin
- pulmonary hypertension
- prodrug
- solvate
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 abstract 2
- ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 abstract 2
- 239000012669 liquid formulation Substances 0.000 abstract 2
- 208000002815 pulmonary hypertension Diseases 0.000 abstract 2
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención proporciona composiciones y métodos para el tratamiento o prevención de hipertensión pulmonar que comprenden administrar una ascomicina, o una sal, solvato, análogo o profármaco farmacéuticamente aceptable de la misma al paciente con hipertensión pulmonar. Se describen en la presente formulaciones líquidas que suministran una ascomicina. La formulación líquida se puede colocar en una cápsula de gelatina blanda.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562207324P | 2015-08-19 | 2015-08-19 | |
PCT/US2016/047148 WO2017031105A1 (en) | 2015-08-19 | 2016-08-16 | Pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018001989A true MX2018001989A (es) | 2018-06-19 |
Family
ID=58051644
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018001989A MX2018001989A (es) | 2015-08-19 | 2016-08-16 | Formulaciones farmaceuticas. |
MX2022013450A MX2022013450A (es) | 2015-08-19 | 2018-02-15 | Formulaciones farmaceuticas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022013450A MX2022013450A (es) | 2015-08-19 | 2018-02-15 | Formulaciones farmaceuticas. |
Country Status (7)
Country | Link |
---|---|
US (4) | US20180243224A1 (es) |
EP (2) | EP4066822A1 (es) |
KR (1) | KR102706357B1 (es) |
AU (2) | AU2016308568A1 (es) |
CA (1) | CA2994859A1 (es) |
MX (2) | MX2018001989A (es) |
WO (1) | WO2017031105A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018209142A2 (en) * | 2017-05-10 | 2018-11-15 | Corcept Therapeutics, Inc. | Octahydro azadecalin formulations |
KR20200134271A (ko) * | 2018-03-19 | 2020-12-01 | 제미니 라보라토리스, 엘엘씨 | 면역억제성 투약형 및 사용 방법 |
WO2020239086A1 (en) | 2019-05-31 | 2020-12-03 | Medical And Pharmaceutical Industry Technology And Development Center | Oral composition and methods for manufacturing the same and treatment |
US11185513B1 (en) * | 2021-05-07 | 2021-11-30 | King Abdulaziz University | Transfersome-containing transdermal film formulations and methods of use |
CN116785244A (zh) * | 2023-06-29 | 2023-09-22 | 上海众强药业有限公司 | 含司来帕格的固体分散体及其制备方法和应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR900506A (fr) | 1943-12-10 | 1945-07-02 | Oerlikon Buehrle Ag | Culasse pour armes à feu à canon coulissant et à chargement par le recul |
PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
US4894366A (en) | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
US5059587A (en) * | 1987-08-03 | 1991-10-22 | Toyo Jozo Company, Ltd. | Physiologically active peptide composition for nasal administration |
US6204243B1 (en) * | 1993-09-01 | 2001-03-20 | Novatis Ag | Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis |
PT649651E (pt) * | 1993-09-28 | 2001-03-30 | Scherer Gmbh R P | Preparacao de capsulas de gelatina macia |
TW450810B (en) | 1997-02-20 | 2001-08-21 | Fujisawa Pharmaceutical Co | Macrolides antibiotic pharmaceutical composition for preventing and treating skin diseases |
US20030216303A1 (en) * | 1998-03-06 | 2003-11-20 | Michael Ambuhl | Emulsion preconcentrates containing cyclosporin or a macrolide |
WO2005020994A1 (en) * | 2003-08-29 | 2005-03-10 | Lifecycle Pharma A/S | Solid dispersions comprising tacrolimus |
KR100678829B1 (ko) * | 2004-12-06 | 2007-02-05 | 한미약품 주식회사 | 타크로리무스의 경구용 마이크로에멀젼 조성물 |
ITMI20070720A1 (it) * | 2007-04-06 | 2008-10-07 | Monteresearch Srl | Composizioni orali contenenti tacrolimus in forma amorfa |
US20090130198A1 (en) * | 2007-11-21 | 2009-05-21 | Innopharmax Inc. | Pharmaceutical composition with enhanced bioavailability |
-
2016
- 2016-08-16 MX MX2018001989A patent/MX2018001989A/es unknown
- 2016-08-16 AU AU2016308568A patent/AU2016308568A1/en not_active Abandoned
- 2016-08-16 EP EP22154078.4A patent/EP4066822A1/en active Pending
- 2016-08-16 KR KR1020187007315A patent/KR102706357B1/ko active Active
- 2016-08-16 EP EP16837688.7A patent/EP3337463A4/en not_active Withdrawn
- 2016-08-16 CA CA2994859A patent/CA2994859A1/en active Pending
- 2016-08-16 WO PCT/US2016/047148 patent/WO2017031105A1/en active Application Filing
- 2016-08-16 US US15/753,033 patent/US20180243224A1/en not_active Abandoned
-
2018
- 2018-02-15 MX MX2022013450A patent/MX2022013450A/es unknown
- 2018-12-14 US US16/220,292 patent/US20190350864A1/en not_active Abandoned
-
2020
- 2020-06-05 US US16/893,998 patent/US20210113477A1/en not_active Abandoned
-
2021
- 2021-09-09 US US17/470,437 patent/US20210401759A1/en not_active Abandoned
-
2022
- 2022-02-26 AU AU2022201340A patent/AU2022201340A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR102706357B1 (ko) | 2024-09-11 |
EP3337463A1 (en) | 2018-06-27 |
US20210113477A1 (en) | 2021-04-22 |
AU2022201340A1 (en) | 2022-03-24 |
EP4066822A1 (en) | 2022-10-05 |
WO2017031105A1 (en) | 2017-02-23 |
US20180243224A1 (en) | 2018-08-30 |
EP3337463A4 (en) | 2019-04-03 |
AU2016308568A1 (en) | 2018-02-22 |
US20210401759A1 (en) | 2021-12-30 |
MX2022013450A (es) | 2022-11-16 |
KR20180041704A (ko) | 2018-04-24 |
US20190350864A1 (en) | 2019-11-21 |
CA2994859A1 (en) | 2017-02-23 |
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