MX2017010806A - Formulacion de acido 18-beta-glicirretinico en combinacion con revesterol y metformina, usos y metodo de fabricacion. - Google Patents
Formulacion de acido 18-beta-glicirretinico en combinacion con revesterol y metformina, usos y metodo de fabricacion.Info
- Publication number
- MX2017010806A MX2017010806A MX2017010806A MX2017010806A MX2017010806A MX 2017010806 A MX2017010806 A MX 2017010806A MX 2017010806 A MX2017010806 A MX 2017010806A MX 2017010806 A MX2017010806 A MX 2017010806A MX 2017010806 A MX2017010806 A MX 2017010806A
- Authority
- MX
- Mexico
- Prior art keywords
- beta
- metformin
- acid
- revesterol
- glicirretinic
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- PYIXHKGTJKCVBJ-UHFFFAOYSA-N Astraciceran Natural products C1OC2=CC(O)=CC=C2CC1C1=CC(OCO2)=C2C=C1OC PYIXHKGTJKCVBJ-UHFFFAOYSA-N 0.000 abstract 1
- NDVRQFZUJRMKKP-UHFFFAOYSA-N Betavulgarin Natural products O=C1C=2C(OC)=C3OCOC3=CC=2OC=C1C1=CC=CC=C1O NDVRQFZUJRMKKP-UHFFFAOYSA-N 0.000 abstract 1
- 229940123208 Biguanide Drugs 0.000 abstract 1
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000450599 DNA viruses Species 0.000 abstract 1
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- 241000186660 Lactobacillus Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- IHPVFYLOGNNZLA-UHFFFAOYSA-N Phytoalexin Natural products COC1=CC=CC=C1C1OC(C=C2C(OCO2)=C2OC)=C2C(=O)C1 IHPVFYLOGNNZLA-UHFFFAOYSA-N 0.000 abstract 1
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 abstract 1
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 210000003484 anatomy Anatomy 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000002717 carbon nanostructure Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000004392 genitalia Anatomy 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 239000000280 phytoalexin Substances 0.000 abstract 1
- 150000001857 phytoalexin derivatives Chemical class 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229940016667 resveratrol Drugs 0.000 abstract 1
- 235000021283 resveratrol Nutrition 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Formulaciones que contienen como principios activos al compuesto ácido 18-beta-Glicirretinico (GA-18ß)en combinación con la fitoalexina resveratrol y la biguadina metformina, utilizando como transportadores nano-estructuras de carbono en una solución polimérica de gel termo-sensible, adicionado con extracto sobrenadante de Lactobacillous sp para su aplicación tópica en diversas regiones anatómicas afectadas por lesiones de tipo displásico y neoplásico, incluyendo la región genital de mujeres y varones con lesiones causadas por diversos ADN virus, como el virus del papiloma humano, herpes virus y cáncer de diversa etiología en los mismos.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2017010806A MX2017010806A (es) | 2017-08-22 | 2017-08-22 | Formulacion de acido 18-beta-glicirretinico en combinacion con revesterol y metformina, usos y metodo de fabricacion. |
PCT/MX2018/050020 WO2019039931A1 (es) | 2017-08-22 | 2018-08-20 | Formulación de ácido 18-beta-glicirretínico en combinación con revesterol y metformina, usos y método de fabricación |
PCT/IB2018/056324 WO2019038678A1 (es) | 2017-08-22 | 2018-08-21 | Formulación de ácido 18-beta-glicirretínico en combinación con revesterol y metformina, usos, y método de fabricación |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2017010806A MX2017010806A (es) | 2017-08-22 | 2017-08-22 | Formulacion de acido 18-beta-glicirretinico en combinacion con revesterol y metformina, usos y metodo de fabricacion. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017010806A true MX2017010806A (es) | 2018-01-18 |
Family
ID=61492274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017010806A MX2017010806A (es) | 2017-08-22 | 2017-08-22 | Formulacion de acido 18-beta-glicirretinico en combinacion con revesterol y metformina, usos y metodo de fabricacion. |
Country Status (2)
Country | Link |
---|---|
MX (1) | MX2017010806A (es) |
WO (2) | WO2019039931A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2019009482A (es) * | 2019-08-08 | 2021-02-09 | Proyectos Atso S A P I De C V | FORMAS FARMACEUTICAS DEL ACIDO 18ß-GLICIRRETINICO. |
CN112370441B (zh) * | 2020-11-24 | 2022-02-01 | 沈阳药科大学 | 白藜芦醇-天然产物组合物及其双磷脂复合物 |
MX2021012629A (es) * | 2021-10-14 | 2023-04-17 | Maria Esther Dragustinovis Ruiz | Formulacion para el manejo y tratamiento antiviral, inmunomodulador y desinflamatorio de la infeccion por el virus del sars-cov2 (covid-19) y sus variante formulada a partir de la sal del acido glisirrisinico y sus deribados de su estructura química, asi como agentes antitusivos y anthistaminicos en jarabe. |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX351117B (es) * | 2011-02-25 | 2017-10-03 | Desarrollos Vph S A De C V | Formulacion de la sal acido glicirricinico en gel termorreversible y acido tricloroacetico para su aplicacion en el tracto genital de mujeres y varones con lesiones causadas por el virus del papiloma humano y cancer en los mismos. |
-
2017
- 2017-08-22 MX MX2017010806A patent/MX2017010806A/es unknown
-
2018
- 2018-08-20 WO PCT/MX2018/050020 patent/WO2019039931A1/es active Application Filing
- 2018-08-21 WO PCT/IB2018/056324 patent/WO2019038678A1/es active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2019039931A1 (es) | 2019-02-28 |
WO2019038678A1 (es) | 2019-02-28 |
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