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MX2017001599A - Anticuerpos novedosos y sus usos. - Google Patents

Anticuerpos novedosos y sus usos.

Info

Publication number
MX2017001599A
MX2017001599A MX2017001599A MX2017001599A MX2017001599A MX 2017001599 A MX2017001599 A MX 2017001599A MX 2017001599 A MX2017001599 A MX 2017001599A MX 2017001599 A MX2017001599 A MX 2017001599A MX 2017001599 A MX2017001599 A MX 2017001599A
Authority
MX
Mexico
Prior art keywords
antigen
antibody
il1rap
novel antibodies
binding
Prior art date
Application number
MX2017001599A
Other languages
English (en)
Inventor
Thoas Fioretos
Marcus Järås
ÅGERSTAM Helena
Ann- Christin Malmborg Hager Cecilia
SJÖSTRÖM Kjell
Svedberg Agneta
Von Wachenfeldt Karin
Original Assignee
Cantargia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantargia Ab filed Critical Cantargia Ab
Publication of MX2017001599A publication Critical patent/MX2017001599A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
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Abstract

La presente invención proporciona un anticuerpo o un fragmento de fijación al antígeno de éste con especificidad de fijación para la proteína accesoria de receptor de interleucina-1 humana (IL1RAP) en donde el anticuerpo o fragmento de fijación al antígeno puede inhibir el dominio 3 de la IL1RAP humana; la invención también proporciona el uso de estos anticuerpos o fragmentos de fijación al antígeno en el tratamiento y/o diagnóstico de tipos de cáncer, tales como leucemias y melanoma.
MX2017001599A 2014-08-06 2015-08-06 Anticuerpos novedosos y sus usos. MX2017001599A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1413913.3A GB201413913D0 (en) 2014-08-06 2014-08-06 Novel antibodies and uses thereof
PCT/EP2015/068208 WO2016020502A1 (en) 2014-08-06 2015-08-06 Novel antibodies and uses thereof

Publications (1)

Publication Number Publication Date
MX2017001599A true MX2017001599A (es) 2017-05-23

Family

ID=51587804

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001599A MX2017001599A (es) 2014-08-06 2015-08-06 Anticuerpos novedosos y sus usos.

Country Status (11)

Country Link
US (2) US10100119B2 (es)
EP (1) EP3193926B1 (es)
JP (1) JP6827411B2 (es)
KR (1) KR20170039685A (es)
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