MX2017000717A - Combinacion de adapaleno y peroxido de benzoilo para el tratamiento del acne grave. - Google Patents
Combinacion de adapaleno y peroxido de benzoilo para el tratamiento del acne grave.Info
- Publication number
- MX2017000717A MX2017000717A MX2017000717A MX2017000717A MX2017000717A MX 2017000717 A MX2017000717 A MX 2017000717A MX 2017000717 A MX2017000717 A MX 2017000717A MX 2017000717 A MX2017000717 A MX 2017000717A MX 2017000717 A MX2017000717 A MX 2017000717A
- Authority
- MX
- Mexico
- Prior art keywords
- adapalene
- benzoyl peroxide
- weight
- treatment
- active ingredients
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona con una composición farmacéutica que comprende 0,3 % por peso de adapaleno, o alguna de sus sales farmacéuticamente aceptables, y 2,5 % por peso de peróxido de benzoílo, como ingredientes activos, destinada al uso en la administración tópica en el tratamiento de las lesiones inflamatorias por acné. La presente invención también se relaciona con un régimen de tratamiento terapéutico para las lesiones por acné de un sujeto que sufre de acné grave. El régimen incluye la aplicación tópica sobre la piel del sujeto, como ingredientes activos, de 0,3 % por peso de adapaleno y 2,5 % por peso de peróxido de benzoílo, combinados en una formula única que libera conjuntamente los ingredientes activos. Por ejemplo, la fórmula única se puede aplicar una o dos veces al día por un período de 8 a 12 semanas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462029043P | 2014-07-25 | 2014-07-25 | |
| PCT/EP2015/066331 WO2016012352A1 (en) | 2014-07-25 | 2015-07-16 | Combination of adapalene and benzoyl peroxide for the treatment of severe acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017000717A true MX2017000717A (es) | 2017-05-01 |
Family
ID=53540775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017000717A MX2017000717A (es) | 2014-07-25 | 2015-07-16 | Combinacion de adapaleno y peroxido de benzoilo para el tratamiento del acne grave. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20170216231A1 (es) |
| EP (1) | EP3171857B1 (es) |
| KR (1) | KR20170035916A (es) |
| CN (1) | CN107072939A (es) |
| AU (1) | AU2015294100A1 (es) |
| BR (1) | BR112017001434A2 (es) |
| CL (1) | CL2017000088A1 (es) |
| CY (1) | CY1124107T1 (es) |
| DK (1) | DK3171857T3 (es) |
| ES (1) | ES2828699T3 (es) |
| HR (1) | HRP20201787T1 (es) |
| HU (1) | HUE051351T2 (es) |
| IL (1) | IL250199A0 (es) |
| LT (1) | LT3171857T (es) |
| MA (1) | MA40179B1 (es) |
| MX (1) | MX2017000717A (es) |
| PT (1) | PT3171857T (es) |
| RS (1) | RS61017B1 (es) |
| RU (1) | RU2017105074A (es) |
| SG (1) | SG11201700449RA (es) |
| SI (1) | SI3171857T1 (es) |
| SM (1) | SMT202000705T1 (es) |
| TW (1) | TW201609082A (es) |
| WO (1) | WO2016012352A1 (es) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2833841B1 (fr) | 2001-12-21 | 2005-07-22 | Galderma Res & Dev | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
| EP1532974B1 (en) | 2002-03-12 | 2008-12-17 | Galderma Research & Development | Composition comprising 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders |
| FR2903603B1 (fr) | 2006-07-13 | 2009-03-20 | Galderma Res & Dev S N C Snc | Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne |
| FR2909000B1 (fr) * | 2006-11-28 | 2009-02-06 | Galderma Res & Dev S N C Snc | Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations. |
| FR2910321B1 (fr) * | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
| CA2720479A1 (en) * | 2008-04-24 | 2009-10-29 | Galderma Research & Development | Combination therapy for acne vulgaris comprising adapalene 0.3% gel with clindamycin/benzoyl peroxide gel |
| US9549905B2 (en) * | 2011-03-23 | 2017-01-24 | The Regents Of The University Of California | Treatment of inflammatory and infectious skin disorders |
| EP3082785A1 (en) * | 2013-12-19 | 2016-10-26 | Galderma Research & Development | Therapy regimen for treating severe acne related diseases |
-
2015
- 2015-07-16 HR HRP20201787TT patent/HRP20201787T1/hr unknown
- 2015-07-16 AU AU2015294100A patent/AU2015294100A1/en not_active Abandoned
- 2015-07-16 US US15/329,170 patent/US20170216231A1/en not_active Abandoned
- 2015-07-16 WO PCT/EP2015/066331 patent/WO2016012352A1/en active Application Filing
- 2015-07-16 SG SG11201700449RA patent/SG11201700449RA/en unknown
- 2015-07-16 RS RS20201325A patent/RS61017B1/sr unknown
- 2015-07-16 HU HUE15736304A patent/HUE051351T2/hu unknown
- 2015-07-16 EP EP15736304.5A patent/EP3171857B1/en active Active
- 2015-07-16 DK DK15736304.5T patent/DK3171857T3/da active
- 2015-07-16 MX MX2017000717A patent/MX2017000717A/es unknown
- 2015-07-16 LT LTEP15736304.5T patent/LT3171857T/lt unknown
- 2015-07-16 BR BR112017001434A patent/BR112017001434A2/pt not_active Application Discontinuation
- 2015-07-16 SI SI201531367T patent/SI3171857T1/sl unknown
- 2015-07-16 KR KR1020177002234A patent/KR20170035916A/ko not_active Withdrawn
- 2015-07-16 CN CN201580040433.2A patent/CN107072939A/zh active Pending
- 2015-07-16 MA MA40179A patent/MA40179B1/fr unknown
- 2015-07-16 SM SM20200705T patent/SMT202000705T1/it unknown
- 2015-07-16 ES ES15736304T patent/ES2828699T3/es active Active
- 2015-07-16 PT PT157363045T patent/PT3171857T/pt unknown
- 2015-07-16 RU RU2017105074A patent/RU2017105074A/ru not_active Application Discontinuation
- 2015-07-24 TW TW104124153A patent/TW201609082A/zh unknown
-
2016
- 2016-12-19 US US15/383,675 patent/US20170095434A1/en not_active Abandoned
-
2017
- 2017-01-13 CL CL2017000088A patent/CL2017000088A1/es unknown
- 2017-01-19 IL IL250199A patent/IL250199A0/en unknown
-
2020
- 2020-10-13 CY CY20201100967T patent/CY1124107T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2828699T3 (es) | 2021-05-27 |
| RU2017105074A (ru) | 2018-08-27 |
| TW201609082A (zh) | 2016-03-16 |
| IL250199A0 (en) | 2017-03-30 |
| CL2017000088A1 (es) | 2017-09-01 |
| US20170216231A1 (en) | 2017-08-03 |
| KR20170035916A (ko) | 2017-03-31 |
| SI3171857T1 (sl) | 2021-01-29 |
| HRP20201787T1 (hr) | 2021-04-16 |
| BR112017001434A2 (pt) | 2017-12-05 |
| HUE051351T2 (hu) | 2021-03-01 |
| US20170095434A1 (en) | 2017-04-06 |
| CN107072939A (zh) | 2017-08-18 |
| RU2017105074A3 (es) | 2019-01-15 |
| PT3171857T (pt) | 2020-11-19 |
| MA40179B1 (fr) | 2020-10-28 |
| RS61017B1 (sr) | 2020-12-31 |
| WO2016012352A1 (en) | 2016-01-28 |
| SMT202000705T1 (it) | 2021-01-05 |
| MA40179A (fr) | 2017-05-31 |
| EP3171857A1 (en) | 2017-05-31 |
| CY1124107T1 (el) | 2022-03-24 |
| EP3171857B1 (en) | 2020-08-19 |
| DK3171857T3 (da) | 2020-09-21 |
| AU2015294100A1 (en) | 2017-01-12 |
| SG11201700449RA (en) | 2017-02-27 |
| LT3171857T (lt) | 2021-01-11 |
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