[go: up one dir, main page]

MX2016005333A - Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos. - Google Patents

Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos.

Info

Publication number
MX2016005333A
MX2016005333A MX2016005333A MX2016005333A MX2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A MX 2016005333 A MX2016005333 A MX 2016005333A
Authority
MX
Mexico
Prior art keywords
haemophilia
inducing tolerance
blood factors
relates
treating haemophilia
Prior art date
Application number
MX2016005333A
Other languages
English (en)
Inventor
Locroix-Desmazes Sébastien
Mondoulet Lucie
DIOSZEGHY Vincent
Original Assignee
Dbv Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dbv Tech filed Critical Dbv Tech
Publication of MX2016005333A publication Critical patent/MX2016005333A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere al tratamiento de la hemofilia. Más específicamente, la invención se refiere a un nuevo método para inducir una tolerancia inmunitaria frente al menos un factor sanguíneo usado para tratar la hemofilia a través de la ruta epicutánea mediante la aplicación de un dispositivo de parche cutáneo que comprende un factor sanguíneo para continuar el tratamiento de la hemofilia. La presente invención también se refiere un dispositivo de parche cutáneo que contiene factor VIII.
MX2016005333A 2013-10-22 2014-10-21 Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos. MX2016005333A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13306453 2013-10-22
PCT/EP2014/072508 WO2015059121A1 (en) 2013-10-22 2014-10-21 Method of treating haemophilia by inducing tolerance to blood factors

Publications (1)

Publication Number Publication Date
MX2016005333A true MX2016005333A (es) 2017-02-15

Family

ID=49513880

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005333A MX2016005333A (es) 2013-10-22 2014-10-21 Método para tratar la hemofilia induciendo tolerancia a factores sanguíneos.

Country Status (12)

Country Link
US (1) US20160220644A1 (es)
EP (1) EP3060242A1 (es)
JP (1) JP2016534083A (es)
KR (1) KR20160090810A (es)
CN (1) CN105848670A (es)
AU (1) AU2014339034A1 (es)
BR (1) BR112016009064A2 (es)
CA (1) CA2928314A1 (es)
EA (1) EA201690817A1 (es)
IL (1) IL245285A0 (es)
MX (1) MX2016005333A (es)
WO (1) WO2015059121A1 (es)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
SE465222C5 (sv) 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
GB2267435A (en) * 1992-06-01 1993-12-08 British Tech Group Factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
AU2002249779A1 (en) * 2000-12-01 2002-08-12 Regents Of The University Of Minnesota Method to treat hemophilia
FR2822049B1 (fr) 2001-03-13 2003-08-01 Dbv Medica 1 Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation
US7635488B2 (en) 2001-03-13 2009-12-22 Dbv Technologies Patches and uses thereof
WO2006003183A1 (de) 2004-07-02 2006-01-12 Alois Jungbauer Peptide zur blockierung von fviii-inhibitoren
DK2363414T3 (da) * 2004-11-12 2022-08-08 Bayer Healthcare Llc Stedstyret modifikation af FVIII
US8071545B2 (en) * 2005-03-15 2011-12-06 Lewis S. Coleman, Md, Inc. Therapies and compositions for controlling the stress mechanism and for stabilizing hemostasis in an organism
EP1985631A1 (en) 2007-04-20 2008-10-29 LFB Biotechnologies Demannosylated recombinant factor VIII for the treatment of patients with hemophiila A
FR2921562B1 (fr) 2007-10-01 2012-06-15 Dbv Tech Dispositif adhesif pour application cutanee
KR20100113478A (ko) * 2007-11-01 2010-10-21 유니버시티 오브 로체스터 증가된 안정성을 갖는 재조합 인자 ⅴⅰⅰⅰ
FR2926466B1 (fr) 2008-01-23 2010-11-12 Dbv Tech Procede de fabrication de patchs par electrospray
GB0801513D0 (en) 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII

Also Published As

Publication number Publication date
AU2014339034A1 (en) 2016-05-19
US20160220644A1 (en) 2016-08-04
EP3060242A1 (en) 2016-08-31
CA2928314A1 (en) 2015-04-30
WO2015059121A1 (en) 2015-04-30
CN105848670A (zh) 2016-08-10
KR20160090810A (ko) 2016-08-01
IL245285A0 (en) 2016-06-30
BR112016009064A2 (pt) 2017-09-19
JP2016534083A (ja) 2016-11-04
EA201690817A1 (ru) 2016-08-31

Similar Documents

Publication Publication Date Title
CL2015000699A1 (es) Métodos para tratamiento de cáncer.
MX377729B (es) Métodos para tratamiento del melanoma.
HK1220980A1 (zh) 用於治療龐貝氏症的方法和組合物
BR112016018170A2 (pt) métodos para tratar doença de alzheimer
PH12015500954B1 (en) Device for extracorporeal blood treatment
AR092899A1 (es) Uso de masitinib para el tratamiento del cancer en subpoblaciones de pacientes identificados que utilizan factores de prediccion
CL2016001076A1 (es) (aza) piridopirazolopirimidinonas e indazolopirimidinonas como inhibidores de fibrinolosis.
MX2017000306A (es) Metodos para tratar hipotension.
EA201690855A1 (ru) Эндоглиновые пептиды для лечения фиброзных заболеваний
NZ722600A (en) Methods of treating mild brain injury
CY1122640T1 (el) Θεραπεια και προφυλαξη δερματιτιδας ακτινοβολιας
MX2015010296A (es) Tratamiento de formas progresivas de esclerosis multiple con laquinimod.
UA117933C2 (uk) Поліпептид, здатний зв'язувати с5-компонент комплементу людини
MX2016016407A (es) Composiciones biofotonicas termoestables y usos de las mismas.
MX2017013047A (es) Tratamiento de dolor.
MX382044B (es) Oxabicicloheptanos y oxabicicloheptenos para el tratamiento de trastornos depresivos y de estrés.
BR112016012248A2 (pt) método de tratamento de nefropatia
MX376887B (es) Separadores para implantes mamarios para el tratamiento de infecciones periprosteticas de los implantes mamarios.
AU350279S (en) An applicator for an apparatus for skin treatment
EA201690445A1 (ru) Лечение рака
EA201690446A1 (ru) Лечение множественной миеломы
MX2019014090A (es) Métodos para el tratamiento de la reservoritis crónica.
EA201590615A1 (ru) Стимулирующие лактацию композиции на основе фосфатидилсерина
BR112016014099A2 (pt) método de tratamento de feridas
EA201691036A1 (ru) Новое соединение для лечения тяжелой гипогликемии

Legal Events

Date Code Title Description
HH Correction or change in general