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MX2015011255A - Composicion a base de flavonoides para uso farmaceutico, nutricional o cosmetico que tiene accion antioxidante potenciada. - Google Patents

Composicion a base de flavonoides para uso farmaceutico, nutricional o cosmetico que tiene accion antioxidante potenciada.

Info

Publication number
MX2015011255A
MX2015011255A MX2015011255A MX2015011255A MX2015011255A MX 2015011255 A MX2015011255 A MX 2015011255A MX 2015011255 A MX2015011255 A MX 2015011255A MX 2015011255 A MX2015011255 A MX 2015011255A MX 2015011255 A MX2015011255 A MX 2015011255A
Authority
MX
Mexico
Prior art keywords
extract
seed
range
nutritional
pharmaceutical
Prior art date
Application number
MX2015011255A
Other languages
English (en)
Other versions
MX363219B (es
Inventor
Giammaria Giuliani
Anna Benedusi
Sergio Baroni
Barbara Marzani
Antonio Mascolo
Antonio Limitone
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Publication of MX2015011255A publication Critical patent/MX2015011255A/es
Publication of MX363219B publication Critical patent/MX363219B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K33/24—Heavy metals; Compounds thereof
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    • A—HUMAN NECESSITIES
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    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
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    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La invención se relaciona con una composición para uso farmacéutico o nutricional o cosmético, se formuló para uso oral o tópico y que posee una actividad antioxidante contra los radicales libres, que comprende: a) un extracto de la semilla u hoja y semilla de Vitis vinífera, que contiene una combinación de los flavonoides de catequina y quercetina en una relación molar en un intervalo desde 6:1 a 3:1, respectivamente, o a') un extracto de la semilla u hoja y semilla de Vitis vinífera, que contiene una combinación de los flavonoides de catequina y quercetina en una relación molar en un intervalo desde 7:1 a 4:1, respectivamente, o a") una mezcla de los extractos a) y a') de Vitis vinífera, o a''') una mezcla de catequina y quercetina en una relación molar en un intervalo desde 7:1 a 3:1, respectivamente, junto con b) un extracto de hoja de olivo, Olea europaea L., que tiene un contenido de hidroxitirosol en un intervalo desde 1% a 30% en peso del extracto, o b') hidroxitirosol en una cantidad igual a una contenida en el extracto b).
MX2015011255A 2013-03-15 2014-03-14 Composición a base de flavonoides para uso farmacéutico, nutricional o cosmético que tiene acción antioxidante potenciada. MX363219B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000397A ITMI20130397A1 (it) 2013-03-15 2013-03-15 Composizione a base di flavonidi per uso farmaceutico, nutrizionale o cosmetico con potenziata azione antiossidante
PCT/EP2014/055162 WO2014140312A1 (en) 2013-03-15 2014-03-14 Flavonoid-based composition for pharmaceutical, nutritional or cosmetic use having potentiated antioxidant action

Publications (2)

Publication Number Publication Date
MX2015011255A true MX2015011255A (es) 2015-12-03
MX363219B MX363219B (es) 2019-03-15

Family

ID=48227405

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011255A MX363219B (es) 2013-03-15 2014-03-14 Composición a base de flavonoides para uso farmacéutico, nutricional o cosmético que tiene acción antioxidante potenciada.

Country Status (21)

Country Link
US (1) US9808498B2 (es)
EP (1) EP2968428B1 (es)
KR (1) KR102213351B1 (es)
AU (1) AU2014230124B2 (es)
BR (1) BR112015019578B1 (es)
CA (1) CA2897262C (es)
CY (1) CY1120628T1 (es)
DK (1) DK2968428T3 (es)
ES (1) ES2683296T3 (es)
HR (1) HRP20181362T1 (es)
HU (1) HUE039977T2 (es)
IT (1) ITMI20130397A1 (es)
LT (1) LT2968428T (es)
MX (1) MX363219B (es)
PL (1) PL2968428T3 (es)
PT (1) PT2968428T (es)
RS (1) RS57563B1 (es)
RU (1) RU2640915C2 (es)
SI (1) SI2968428T1 (es)
SM (1) SMT201800528T1 (es)
WO (1) WO2014140312A1 (es)

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Publication number Priority date Publication date Assignee Title
JP6033382B1 (ja) 2015-10-01 2016-11-30 小豆島ヘルシーランド株式会社 オリーヴ葉エキス及びその製造方法
CN105726556A (zh) * 2016-03-23 2016-07-06 中国科学院兰州化学物理研究所 一种具有降血脂作用的组合物
US10485745B2 (en) * 2016-04-29 2019-11-26 L'oreal UV-A/UV-B sunscreen composition
AU2017442781B2 (en) * 2017-12-15 2020-10-01 Tsukasa Nagao Health food and cosmetics for increasing the amount of apoptosis cells and decreasing the amount of necrosis cells and a method of manufacturing a sprout-forcing grape seed-derived ingredient for increasing the amount of apoptosis cells and decreasing the amount of necrosis cells
ES2689105B8 (es) * 2018-04-30 2019-05-28 Monteloeder S L Composición de extractos vegetales con flavonoides para paliar los múltiples efectos de la contaminación del aire sobre la piel
IT201900015018A1 (it) * 2019-08-26 2021-02-26 Epitech Group S P A Composizione di n-palmitoil-etanolamide e rutina in forma comicronizzata
US11583480B2 (en) 2019-08-27 2023-02-21 L'oreal Sunscreen composition with a high UV filter load
IT202000015493A1 (it) 2020-06-26 2021-12-26 Fondazione St Italiano Tecnologia Estratto di vinacce di uva bianca di vitis vinifera, relative composizioni e usi
KR20250043425A (ko) * 2022-08-03 2025-03-28 나노몰 테크놀로지스, 에스.엘. 글루코스 유래 계면활성제 및 피토스테롤을 기반으로 한 소포

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
IT1320080B1 (it) * 2000-10-25 2003-11-18 Giuliani Spa Composizione per uso farmaceutico o dietetico.
FR2883884B1 (fr) * 2005-03-30 2012-11-09 Lallemand Sas Preparation de levures a proprietes anti-oxydantes ameliorees et leurs applications
EP1790234B1 (en) * 2005-11-28 2014-07-02 Chr. Hansen A/S Natural antioxidant additive for feed and drinking water
FR2942224B1 (fr) * 2009-02-18 2012-11-30 Centre De Cooperation Internationale En Rech Agronomique Pour Le Developpement Cirad Procede d'extraction de composes phenoliques a partir d'eau de vegetation de l'olive et preparation d'extrait titre en polyphenols d'olive et de raisin
EP2364697A1 (en) * 2010-03-12 2011-09-14 Cor.Con. International S.r.L. Antioxidant composition for reducing oxidative stress ascribable to the treatment with hormonal contraceptive drugs
ES2391211B1 (es) * 2011-05-04 2013-10-02 Select Botanical, S.L. Combinacion sinergica de polifenoles

Also Published As

Publication number Publication date
RS57563B1 (sr) 2018-10-31
ES2683296T3 (es) 2018-09-26
RU2640915C2 (ru) 2018-01-12
CA2897262C (en) 2021-03-02
SMT201800528T1 (it) 2018-11-09
HUE039977T2 (hu) 2019-02-28
HRP20181362T1 (hr) 2018-10-19
EP2968428B1 (en) 2018-05-30
LT2968428T (lt) 2018-09-10
SI2968428T1 (sl) 2018-10-30
BR112015019578A2 (pt) 2017-07-18
AU2014230124A1 (en) 2015-07-23
KR102213351B1 (ko) 2021-02-08
US20160030500A1 (en) 2016-02-04
AU2014230124B2 (en) 2018-07-12
WO2014140312A1 (en) 2014-09-18
DK2968428T3 (en) 2018-08-13
KR20150127578A (ko) 2015-11-17
PL2968428T3 (pl) 2018-11-30
PT2968428T (pt) 2018-10-24
EP2968428A1 (en) 2016-01-20
ITMI20130397A1 (it) 2014-09-16
US9808498B2 (en) 2017-11-07
CA2897262A1 (en) 2014-09-18
BR112015019578B1 (pt) 2021-01-26
MX363219B (es) 2019-03-15
RU2015127022A (ru) 2017-01-12
CY1120628T1 (el) 2019-12-11

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