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MX2015009819A - Anticuerpo humano especifico a metapneumovirus humano, o fragmento de union al antigeno del mismo. - Google Patents

Anticuerpo humano especifico a metapneumovirus humano, o fragmento de union al antigeno del mismo.

Info

Publication number
MX2015009819A
MX2015009819A MX2015009819A MX2015009819A MX2015009819A MX 2015009819 A MX2015009819 A MX 2015009819A MX 2015009819 A MX2015009819 A MX 2015009819A MX 2015009819 A MX2015009819 A MX 2015009819A MX 2015009819 A MX2015009819 A MX 2015009819A
Authority
MX
Mexico
Prior art keywords
human
antigen
binding fragment
antibody specific
metapneumovirus
Prior art date
Application number
MX2015009819A
Other languages
English (en)
Inventor
Kenzo Takada
Kantou Nakajima
Original Assignee
Evec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evec Inc filed Critical Evec Inc
Publication of MX2015009819A publication Critical patent/MX2015009819A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención proporciona: un nuevo anticuerpo monoclonal derivado de humano que une específicamente a la proteína F del metapneumovirus humano y que neutraliza el metapneumovirus humano; un fragmento de unión al antígeno de dicho anticuerpo; y una composición farmacéutica que incluye dicho anticuerpo o dicho fragmento de unión al antígeno del mismo.
MX2015009819A 2013-01-28 2014-01-28 Anticuerpo humano especifico a metapneumovirus humano, o fragmento de union al antigeno del mismo. MX2015009819A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013013599 2013-01-28
PCT/JP2014/051866 WO2014115893A1 (ja) 2013-01-28 2014-01-28 ヒト・メタニューモウイルスに特異的なヒト抗体もしくはその抗原結合性断片

Publications (1)

Publication Number Publication Date
MX2015009819A true MX2015009819A (es) 2015-10-29

Family

ID=51227681

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015009819A MX2015009819A (es) 2013-01-28 2014-01-28 Anticuerpo humano especifico a metapneumovirus humano, o fragmento de union al antigeno del mismo.

Country Status (13)

Country Link
US (1) US20150322137A1 (es)
EP (1) EP2966086A4 (es)
JP (1) JPWO2014115893A1 (es)
KR (1) KR20150135231A (es)
CN (1) CN104955839A (es)
AU (1) AU2014208456A1 (es)
BR (1) BR112015017981A2 (es)
CA (1) CA2899052A1 (es)
IL (1) IL240161A0 (es)
MX (1) MX2015009819A (es)
PH (1) PH12015501650A1 (es)
RU (1) RU2015129655A (es)
WO (1) WO2014115893A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11414497B2 (en) 2016-04-13 2022-08-16 Orimabs Ltd. Anti-PSMA antibodies and use thereof
CN105693829B (zh) * 2016-04-14 2022-03-15 青岛易邦生物工程有限公司 一种b型禽偏肺病毒f蛋白
GB201618432D0 (en) * 2016-11-01 2016-12-14 Matn Scient Ltd Detection and treatment of demyelinating diseases
US20230085439A1 (en) * 2019-05-21 2023-03-16 University Of Georgia Research Foundation, Inc. Antibodies that bind human metapneumovirus fusion protein and their use
CN119143871B (zh) * 2024-11-20 2025-02-07 首都儿科研究所 用于人偏肺病毒检测的单克隆抗体、检测试剂及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0500244A3 (en) 2001-01-19 2011-03-28 Vironovative Bv A virus causing respiratory tract illness in suspectible mammals
EP2327418A1 (en) 2002-02-21 2011-06-01 MedImmune, LLC Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from other viruses
CA2592015A1 (en) 2004-12-27 2006-07-06 Progenics Pharmaceuticals (Nevada), Inc. Orally deliverable and anti-toxin antibodies and methods for making and using them
JP4976376B2 (ja) 2005-04-08 2012-07-18 メディミューン，エルエルシー 哺乳動物メタニューモウイルスに対する抗体
JP4997108B2 (ja) 2005-07-22 2012-08-08 協和発酵キリン株式会社 遺伝子組換え抗体組成物
FR2891522B1 (fr) 2005-10-04 2009-05-08 Promiles Sa Bicyclette a longueur de cadre ajustable.
ES2602439T3 (es) 2006-03-03 2017-02-21 The Chemo-Sero-Therapeutic Research Institute Anticuerpo modificado con bioactividad mejorada
WO2008043052A2 (en) 2006-10-04 2008-04-10 The Scripps Research Institute Human antibodies neutralizing human metapneumovirus
US8362210B2 (en) 2010-01-19 2013-01-29 Xencor, Inc. Antibody variants with enhanced complement activity
EA030319B1 (ru) 2012-03-20 2018-07-31 Хумабс Биомед Са Антитела, нейтрализующие rsv, mpv и pvm, и их применения

Also Published As

Publication number Publication date
EP2966086A4 (en) 2016-07-27
WO2014115893A1 (ja) 2014-07-31
CN104955839A (zh) 2015-09-30
RU2015129655A (ru) 2017-03-07
IL240161A0 (en) 2015-09-24
BR112015017981A2 (pt) 2017-11-21
KR20150135231A (ko) 2015-12-02
EP2966086A1 (en) 2016-01-13
JPWO2014115893A1 (ja) 2017-01-26
PH12015501650A1 (en) 2015-10-19
AU2014208456A1 (en) 2015-08-13
US20150322137A1 (en) 2015-11-12
CA2899052A1 (en) 2014-07-31

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