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MX2015005753A - Agentes antimicrobianos. - Google Patents

Agentes antimicrobianos.

Info

Publication number
MX2015005753A
MX2015005753A MX2015005753A MX2015005753A MX2015005753A MX 2015005753 A MX2015005753 A MX 2015005753A MX 2015005753 A MX2015005753 A MX 2015005753A MX 2015005753 A MX2015005753 A MX 2015005753A MX 2015005753 A MX2015005753 A MX 2015005753A
Authority
MX
Mexico
Prior art keywords
antimicrobial agents
compounds
salts
useful
formula
Prior art date
Application number
MX2015005753A
Other languages
English (en)
Other versions
MX364443B (es
Inventor
Yongzheng Zhang
Edmond J Lavoie
Ajit Pharhi
Daniel S Pilch
Malvika Kaul
Original Assignee
Univ Rutgers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers filed Critical Univ Rutgers
Publication of MX2015005753A publication Critical patent/MX2015005753A/es
Publication of MX364443B publication Critical patent/MX364443B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/88—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having the nitrogen atom of at least one of the carboxamide groups further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epidemiology (AREA)

Abstract

La invención proporciona compuestos de la fórmula (I): en donde R1-R3, n y W tienen cualquiera de los valores definidos en la descripción, y sales de los mismos. Los compuestos tienen buena solubilidad y son útiles para tratar infecciones bacterianas.
MX2015005753A 2012-11-08 2013-11-08 Agentes antimicrobianos. MX364443B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261724182P 2012-11-08 2012-11-08
PCT/US2013/069316 WO2014074932A1 (en) 2012-11-08 2013-11-08 Antimicrobial agents

Publications (2)

Publication Number Publication Date
MX2015005753A true MX2015005753A (es) 2015-12-16
MX364443B MX364443B (es) 2019-04-26

Family

ID=49622917

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015005753A MX364443B (es) 2012-11-08 2013-11-08 Agentes antimicrobianos.

Country Status (16)

Country Link
US (3) US20150307517A1 (es)
EP (1) EP2917212B1 (es)
JP (1) JP6411355B2 (es)
KR (1) KR102163608B1 (es)
CN (1) CN104981469B (es)
AU (1) AU2013342095B2 (es)
BR (1) BR112015010570B8 (es)
CA (1) CA2891092C (es)
DK (1) DK2917212T3 (es)
ES (1) ES2748665T3 (es)
IL (1) IL238677B (es)
MX (1) MX364443B (es)
PL (1) PL2917212T3 (es)
SG (1) SG11201503620RA (es)
WO (1) WO2014074932A1 (es)
ZA (1) ZA201503372B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013142712A1 (en) * 2012-03-21 2013-09-26 Rutgers, The State University Of New Jersey Antimicrobial agents
US9458150B2 (en) 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents
WO2015179697A1 (en) * 2014-05-21 2015-11-26 Taxis Pharmaceuticals, Inc. Compounds for the treatment of bacterial infections
JP2019507801A (ja) * 2016-02-25 2019-03-22 タクシス ファーマシューティカルズ， インコーポレイテッド 合成プロセス及び中間体
US10774093B2 (en) 2017-03-30 2020-09-15 Taxis Pharmaceuticals, Inc. Synthetic processes and synthetic intermediates
EP3752143B1 (en) * 2018-02-13 2025-04-09 Rutgers, The State University of New Jersey Antibacterial agents: o-alkyl-deuterated pyronins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US190723A (en) * 1877-05-15 Improvement in washing-machines
US1375188A (en) * 1919-04-02 1921-04-19 Stern John Garter-support
DE3478573D1 (en) * 1983-09-01 1989-07-13 Duphar Int Res Benzoyl urea derivatives having anti-tumor activity
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
JPH11209350A (ja) * 1998-01-26 1999-08-03 Eisai Co Ltd 含窒素複素環誘導体およびその医薬
CA2372079A1 (en) * 1999-05-05 2000-11-09 Aaron H. Leeman Novel catechols as antimicrobial agents
JPWO2002044127A1 (ja) * 2000-11-29 2004-04-02 杏林製薬株式会社 置換カルボン酸誘導体
US20050113450A1 (en) * 2002-08-23 2005-05-26 Atli Thorarensen Antibacterial agents
GB0605881D0 (en) * 2006-03-23 2006-05-03 Prolysis Ltd Antibacterial Agents
DK1996180T3 (da) * 2006-03-23 2011-10-31 Biota Scient Management Benzamid- og pyridylamidderivater som antibakterielle midler
JP5369000B2 (ja) * 2007-12-25 2013-12-18 キッセイ薬品工業株式会社 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途
JP5883591B2 (ja) * 2010-08-06 2016-03-15 キッセイ薬品工業株式会社 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途
CN103635466A (zh) * 2011-04-20 2014-03-12 生物科学管理有限责任公司 芳族酰胺及其用途
WO2013142712A1 (en) * 2012-03-21 2013-09-26 Rutgers, The State University Of New Jersey Antimicrobial agents
US9458150B2 (en) * 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents

Also Published As

Publication number Publication date
BR112015010570B1 (pt) 2020-03-17
US20250206755A1 (en) 2025-06-26
EP2917212B1 (en) 2019-06-12
CN104981469B (zh) 2018-03-20
PL2917212T3 (pl) 2020-03-31
US20180179225A1 (en) 2018-06-28
BR112015010570A2 (pt) 2017-07-11
BR112015010570B8 (pt) 2021-04-20
CA2891092C (en) 2020-12-15
ES2748665T3 (es) 2020-03-17
ZA201503372B (en) 2016-07-27
JP2016501190A (ja) 2016-01-18
CA2891092A1 (en) 2014-05-15
AU2013342095A1 (en) 2015-05-21
JP6411355B2 (ja) 2018-10-24
SG11201503620RA (en) 2015-06-29
KR102163608B1 (ko) 2020-10-07
EP2917212A1 (en) 2015-09-16
AU2013342095B2 (en) 2017-09-28
MX364443B (es) 2019-04-26
WO2014074932A1 (en) 2014-05-15
HK1215031A1 (en) 2016-08-12
US20150307517A1 (en) 2015-10-29
IL238677A0 (en) 2015-06-30
KR20150096392A (ko) 2015-08-24
IL238677B (en) 2019-05-30
CN104981469A (zh) 2015-10-14
DK2917212T3 (da) 2019-09-23

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