MX2014001920A - Proteina de fusion acortada de tetranectina-apolipoproteina a-i, una particula lipidica que la contiene, y usos de la misma. - Google Patents
Proteina de fusion acortada de tetranectina-apolipoproteina a-i, una particula lipidica que la contiene, y usos de la misma.Info
- Publication number
- MX2014001920A MX2014001920A MX2014001920A MX2014001920A MX2014001920A MX 2014001920 A MX2014001920 A MX 2014001920A MX 2014001920 A MX2014001920 A MX 2014001920A MX 2014001920 A MX2014001920 A MX 2014001920A MX 2014001920 A MX2014001920 A MX 2014001920A
- Authority
- MX
- Mexico
- Prior art keywords
- apolipoprotein
- fusion protein
- lipid particle
- particle containing
- shortened tetranectin
- Prior art date
Links
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 239000002245 particle Substances 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
Abstract
Aquí se describe una proteína de fusión tetranectina-apolipoproteí na A-I acortada y una partícula lipídica que comprende la proteína de fusión tetranectina-apolipoproteína A-I acortada así como la utilización de las mismas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11178746 | 2011-08-25 | ||
PCT/EP2012/066301 WO2013026860A1 (en) | 2011-08-25 | 2012-08-22 | Shortened tetranectin-apolipoprotein a-i fusion protein, a lipid particle containing it, and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014001920A true MX2014001920A (es) | 2014-04-14 |
Family
ID=46704687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014001920A MX2014001920A (es) | 2011-08-25 | 2012-08-22 | Proteina de fusion acortada de tetranectina-apolipoproteina a-i, una particula lipidica que la contiene, y usos de la misma. |
Country Status (11)
Country | Link |
---|---|
US (2) | US8791063B2 (es) |
EP (1) | EP2748191A1 (es) |
JP (2) | JP6207507B2 (es) |
KR (1) | KR20140054115A (es) |
CN (1) | CN103703023A (es) |
AR (1) | AR087640A1 (es) |
BR (1) | BR112013033562A2 (es) |
CA (1) | CA2838070A1 (es) |
MX (1) | MX2014001920A (es) |
RU (1) | RU2014108240A (es) |
WO (1) | WO2013026860A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018223118A1 (en) * | 2017-06-02 | 2018-12-06 | The Feinstein Institute For Medical Research | Use of tetranectin and peptide agonists to treat inflammatory diseases |
Family Cites Families (51)
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US4608347A (en) | 1982-04-15 | 1986-08-26 | Bernstam Victor A | Compositions, uses and methods creating reverse micelles for the clarification of biological fluids to obtain undistorted assay of analytes following clarification |
DE4192335T1 (de) | 1990-09-18 | 1993-10-07 | Biotech Australia Pty Ltd | T-Zell-Epitope |
SE9103701D0 (sv) | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
ES2231991T3 (es) | 1997-06-11 | 2005-05-16 | Borean Pharma A/S | Modulo de trimerizacion. |
US6518412B1 (en) | 1997-09-29 | 2003-02-11 | Jean-Louis Dasseux | Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
EP0972838B1 (en) | 1998-07-15 | 2004-09-15 | Roche Diagnostics GmbH | Escherichia coli host/vector system based on antibiotic-free selection by complementation of an auxotrophy |
US6291245B1 (en) | 1998-07-15 | 2001-09-18 | Roche Diagnostics Gmbh | Host-vector system |
WO2001079446A2 (en) | 2000-04-14 | 2001-10-25 | Hyseq, Inc. | Materials and methods relating to lipid metabolism |
CN1268641C (zh) * | 2000-11-10 | 2006-08-09 | 普罗蒂奥制药公司 | 载脂蛋白类似物 |
ITMI20021058A1 (it) | 2002-05-17 | 2003-11-17 | Chiesi Farma Spa | Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito |
NZ537006A (en) | 2002-05-17 | 2008-01-31 | Esperion Therapeutics Inc | The use of apolipoprotein A-I Milano, for the manufacture ofa composition for treating preventing or reducing ischemic reperfusion injury in a tissue or organ |
JP2006507223A (ja) * | 2002-05-17 | 2006-03-02 | エスペリオン セラピューティクス,インコーポレイテッド | 脂質代謝異常疾患の治療方法 |
WO2004005335A2 (en) * | 2002-07-05 | 2004-01-15 | Borean Pharma A/S | Multimerised growth hormone fusion proteins |
CA2443365C (en) | 2002-11-19 | 2010-01-12 | F. Hoffmann-La Roche Ag | Methods for the recombinant production of antifusogenic peptides |
US20040180445A1 (en) | 2003-03-12 | 2004-09-16 | Domanico Michael J. | Methods and compositions for purification of nucleic acid from a host cell |
ATE312939T1 (de) | 2003-06-12 | 2005-12-15 | Verfahren zur rekombinanten herstellung von polypeptiden | |
PE20050438A1 (es) | 2003-10-20 | 2005-06-14 | Esperion Therapeutics Inc | Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos |
WO2005041886A2 (en) | 2003-10-31 | 2005-05-12 | Metaphore Pharmaceuticals, Inc. | Methods for generating or increasing revenues related to pain inhibitor commerce |
KR20060108739A (ko) | 2003-12-30 | 2006-10-18 | 와이어쓰 | 개선된 내약성을 가지는 면역원성 조성물 중 소수성단백질의 제제 |
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US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
US20090143276A1 (en) * | 2007-10-08 | 2009-06-04 | Anaphore, Inc. | Trimeric IL-1Ra |
KR100560102B1 (ko) | 2004-06-25 | 2006-03-13 | 한국생명공학연구원 | 프로아포리포단백질 a-ⅰ 변이체와, 이를 포함하는고지혈증 또는 동맥경화증 예방 및 치료제 |
EP1848812A4 (en) | 2004-10-01 | 2011-11-09 | Life Technologies Corp | SUPPLY BUFFERS, SYSTEMS AND METHODS FOR THE IN VITRO SYNTHESIS OF BIOMOLECULES |
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US20060160721A1 (en) | 2004-12-22 | 2006-07-20 | Baylor College Of Medicine | Method of plasma lipidation to prevent, inhibit and/or reverse atherosclerosis |
US8206750B2 (en) * | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
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US20070254832A1 (en) | 2006-02-17 | 2007-11-01 | Pressler Milton L | Methods for the treatment of macular degeneration and related eye conditions |
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WO2008013885A2 (en) | 2006-07-25 | 2008-01-31 | Stratagene California | Zwitterionic detergents for the storage and use of dna polymerases |
EA021282B1 (ru) | 2006-08-10 | 2015-05-29 | ПЛАНТЕКНО С.р.л. | ДИМЕРНЫЕ И/ИЛИ ОЛИГОМЕРНЫЕ ФОРМЫ МУТЕИНА БЕЛКА ApoA-1 ЧЕЛОВЕКА, ПОЛУЧЕННЫЕ В СЕМЕНАХ РАСТЕНИЙ, И ИХ ПРИМЕНЕНИЕ |
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AR082644A1 (es) | 2010-08-30 | 2012-12-19 | Hoffmann La Roche | Tetranectina-apolipoproteina a-i, particulas lipidicas que la contiene y utilizacion de la misma relacionado con el metabolismo de los lipidos y las enfermedades cardiovasculares |
JP6116565B2 (ja) | 2011-08-25 | 2017-04-19 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 陽イオンおよび陰イオン交換クロマトグラフィー法 |
MX2014010092A (es) | 2012-02-29 | 2014-09-16 | Hoffmann La Roche | Escision enzimatica en columna. |
KR20150009953A (ko) | 2012-02-29 | 2015-01-27 | 에프. 호프만-라 로슈 아게 | 1→3 해독 프레임 이동의 감소 방법 |
CA2860735A1 (en) | 2012-02-29 | 2013-09-06 | F. Hoffmann-La Roche Ag | Method for reduction of 1->2 reading frame shifts |
-
2012
- 2012-08-22 EP EP12748504.3A patent/EP2748191A1/en not_active Withdrawn
- 2012-08-22 CA CA2838070A patent/CA2838070A1/en not_active Abandoned
- 2012-08-22 BR BR112013033562A patent/BR112013033562A2/pt not_active IP Right Cessation
- 2012-08-22 JP JP2014526485A patent/JP6207507B2/ja not_active Expired - Fee Related
- 2012-08-22 KR KR1020147004659A patent/KR20140054115A/ko not_active Withdrawn
- 2012-08-22 RU RU2014108240/10A patent/RU2014108240A/ru not_active Application Discontinuation
- 2012-08-22 CN CN201280036904.9A patent/CN103703023A/zh active Pending
- 2012-08-22 MX MX2014001920A patent/MX2014001920A/es unknown
- 2012-08-22 US US13/592,183 patent/US8791063B2/en not_active Expired - Fee Related
- 2012-08-22 WO PCT/EP2012/066301 patent/WO2013026860A1/en active Application Filing
- 2012-08-23 AR ARP120103098A patent/AR087640A1/es not_active Application Discontinuation
-
2014
- 2014-06-25 US US14/315,187 patent/US9139640B2/en not_active Expired - Fee Related
-
2017
- 2017-04-27 JP JP2017088198A patent/JP2017171670A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2748191A1 (en) | 2014-07-02 |
US8791063B2 (en) | 2014-07-29 |
JP2014529602A (ja) | 2014-11-13 |
US20130231273A1 (en) | 2013-09-05 |
CA2838070A1 (en) | 2013-02-28 |
CN103703023A (zh) | 2014-04-02 |
US20150011459A1 (en) | 2015-01-08 |
BR112013033562A2 (pt) | 2017-02-14 |
US9139640B2 (en) | 2015-09-22 |
JP6207507B2 (ja) | 2017-10-04 |
RU2014108240A (ru) | 2015-09-27 |
KR20140054115A (ko) | 2014-05-08 |
JP2017171670A (ja) | 2017-09-28 |
WO2013026860A1 (en) | 2013-02-28 |
AR087640A1 (es) | 2014-04-09 |
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