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MX2012014096A - Métodos para mejorar el diagnóstico de enfermedad intestinal inflamatoria. - Google Patents

Métodos para mejorar el diagnóstico de enfermedad intestinal inflamatoria.

Info

Publication number
MX2012014096A
MX2012014096A MX2012014096A MX2012014096A MX2012014096A MX 2012014096 A MX2012014096 A MX 2012014096A MX 2012014096 A MX2012014096 A MX 2012014096A MX 2012014096 A MX2012014096 A MX 2012014096A MX 2012014096 A MX2012014096 A MX 2012014096A
Authority
MX
Mexico
Prior art keywords
inflammatory bowel
bowel disease
methods
disease diagnosis
improving inflammatory
Prior art date
Application number
MX2012014096A
Other languages
English (en)
Inventor
Sharat Singh
Fred Princen
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of MX2012014096A publication Critical patent/MX2012014096A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención proporciona métodos y sistemas para diagnosticar la colitis ulcerosa (UC), subtipo de enfermedad inflamatoria intestinal (lBD) al detectar la presencia o ausencia de uno o más alelos variantes en los genes CLI1, MDRI y/o ATG16L1. De forma favorable, con la presente invención, es posible proporcionar un diagnóstico de UC y diferenciar entre UC y enfermedad de Chron (CD) con mayor precisión.
MX2012014096A 2010-06-04 2011-06-03 Métodos para mejorar el diagnóstico de enfermedad intestinal inflamatoria. MX2012014096A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35183710P 2010-06-04 2010-06-04
US35414110P 2010-06-11 2010-06-11
US39358810P 2010-10-15 2010-10-15
PCT/US2011/039174 WO2011153501A2 (en) 2010-06-04 2011-06-03 Methods for improving inflammatory bowel disease diagnosis

Publications (1)

Publication Number Publication Date
MX2012014096A true MX2012014096A (es) 2013-04-19

Family

ID=45067328

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012014096A MX2012014096A (es) 2010-06-04 2011-06-03 Métodos para mejorar el diagnóstico de enfermedad intestinal inflamatoria.

Country Status (6)

Country Link
US (1) US20130203053A1 (es)
EP (1) EP2576838A4 (es)
JP (1) JP2013528389A (es)
CA (1) CA2801575A1 (es)
MX (1) MX2012014096A (es)
WO (1) WO2011153501A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015168699A1 (en) * 2014-05-02 2015-11-05 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (mruc) requiring colectomy
CN110544517A (zh) 2011-05-10 2019-12-06 雀巢产品有限公司 用于个体化治疗管理的疾病活动性表征方法
WO2013059732A1 (en) 2011-10-21 2013-04-25 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis
MX358730B (es) * 2012-10-05 2018-09-03 Nestec Sa Metodos para predecir y monitorear cicatrizacion de la mucosa.
EP3094973B1 (en) 2013-11-07 2020-07-29 Diagnodus Limited Biomarkers
KR20230003433A (ko) * 2016-05-20 2023-01-05 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
CA3064529C (en) 2017-05-31 2021-12-14 Prometheus Biosciences, Inc. Methods for assessing mucosal healing in crohn's disease patients
US11861491B2 (en) 2017-10-16 2024-01-02 Illumina, Inc. Deep learning-based pathogenicity classifier for promoter single nucleotide variants (pSNVs)
KR102748353B1 (ko) * 2017-10-16 2024-12-31 일루미나, 인코포레이티드 심층 컨볼루션 신경망을 트레이닝하기 위한 심층 학습-기반 기술
CN108929913A (zh) * 2018-08-21 2018-12-04 潍坊德诺泰克生物科技有限公司 用于检测rs2032582的引物探针组及其应用
PH12022550773A1 (en) * 2019-09-30 2023-05-03 Univ Cape Town Method for diagnosing tuberculosis in urine samples
CN111180012A (zh) * 2019-12-27 2020-05-19 哈尔滨工业大学 一种基于经验贝叶斯与孟德尔随机化融合的基因识别方法
CN116863995B (zh) * 2023-08-29 2024-05-14 北京大学第一医院 Alpk2，itga11，esyt1，cdh17在预测药物出血中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874233A (en) * 1996-04-12 1999-02-23 Cedars-Sinai Medical Center Methods of diagnosing a clinical subtype of Crohn's disease with features of ulcerative colitis
AU2003298703A1 (en) * 2002-11-22 2004-06-18 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
WO2004091372A2 (en) * 2003-04-11 2004-10-28 Cedars-Sinai Medical Center Methods of assessing crohn’s disease patient phenotype by i2, ompc and asca serologic response
WO2009003274A1 (en) * 2007-06-29 2009-01-08 The Hospital For Sick Children Susceptibility gene for inflammatory bowel disease
MX2010005893A (es) * 2007-11-29 2011-03-04 Genentech Inc Star Marcadores de expresion genica para enfermedad inflamatoria de intestino.
SI2257643T1 (sl) * 2008-02-19 2018-12-31 The Children's Hospital Of Philadelphia Identifikacija predelov vnetne črevesne bolezni z začetkom v otroštvu in metode za njeno uporabo za diagnozo in zdravljenje te bolezni
NZ619527A (en) * 2009-04-14 2015-06-26 Nestec Sa Inflammatory bowel disease prognostics

Also Published As

Publication number Publication date
WO2011153501A2 (en) 2011-12-08
JP2013528389A (ja) 2013-07-11
EP2576838A4 (en) 2019-05-15
CA2801575A1 (en) 2011-12-08
EP2576838A2 (en) 2013-04-10
US20130203053A1 (en) 2013-08-08
WO2011153501A9 (en) 2012-04-05

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Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: NESTEC S.A.

FA Abandonment or withdrawal