MX2012003489A - Polimorfos novedosos de rebaudiosida c y metodos para elaborarlos y utilizarlos. - Google Patents
Polimorfos novedosos de rebaudiosida c y metodos para elaborarlos y utilizarlos.Info
- Publication number
- MX2012003489A MX2012003489A MX2012003489A MX2012003489A MX2012003489A MX 2012003489 A MX2012003489 A MX 2012003489A MX 2012003489 A MX2012003489 A MX 2012003489A MX 2012003489 A MX2012003489 A MX 2012003489A MX 2012003489 A MX2012003489 A MX 2012003489A
- Authority
- MX
- Mexico
- Prior art keywords
- rebaudioside
- making
- methods
- same
- novel polymorphs
- Prior art date
Links
- QSRAJVGDWKFOGU-WBXIDTKBSA-N rebaudioside c Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]1(CC[C@H]2[C@@]3(C)[C@@H]([C@](CCC3)(C)C(=O)O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)CC3)C(=C)C[C@]23C1 QSRAJVGDWKFOGU-WBXIDTKBSA-N 0.000 title abstract 12
- 239000001776 FEMA 4720 Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polymers & Plastics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Seasonings (AREA)
- Saccharide Compounds (AREA)
Abstract
Se describen modalidades de la presente invención que comprenden un método para producir y purificar la rebaudiosida C. En particular, la presente invención se refiere a un método para la purificación de rebaudiosida C, composiciones para obtener un producto de rebaudiosida C substancialmente puro, utilizando uno o más pasos de cristalización. Las formas polimórficas resultantes de la rebaudiosida C composiciones de la rebaudiosida C es substancialmente pura y sus usos también se describen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24480309P | 2009-09-22 | 2009-09-22 | |
PCT/US2010/049763 WO2011037959A1 (en) | 2009-09-22 | 2010-09-22 | Novel polymorphs of rebaudioside c and methods for making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012003489A true MX2012003489A (es) | 2012-07-30 |
Family
ID=43216273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012003489A MX2012003489A (es) | 2009-09-22 | 2010-09-22 | Polimorfos novedosos de rebaudiosida c y metodos para elaborarlos y utilizarlos. |
Country Status (10)
Country | Link |
---|---|
US (2) | US20120230922A1 (es) |
EP (1) | EP2480097A1 (es) |
CN (1) | CN102595932B (es) |
AU (1) | AU2010298437B2 (es) |
BR (1) | BR112012006282A2 (es) |
CA (1) | CA2773917A1 (es) |
MX (1) | MX2012003489A (es) |
SG (1) | SG178920A1 (es) |
WO (1) | WO2011037959A1 (es) |
ZA (1) | ZA201201542B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110224311A1 (en) * | 2009-07-17 | 2011-09-15 | Palmer R Kyle | Natural Product Sweetness Enhancers |
US8524785B2 (en) * | 2009-09-04 | 2013-09-03 | International Flavors And Fragrances Inc. | Methods for using rebaudioside C as a flavor enhancer |
CA3176307A1 (en) | 2010-06-02 | 2011-12-08 | Evolva Nutrition, Inc. | Recombinant production of steviol glycosides |
EP2742142B2 (en) | 2011-08-08 | 2020-03-25 | Evolva SA | Recombinant production of steviol glycosides |
US8889841B2 (en) | 2011-11-18 | 2014-11-18 | International Flavors & Fragrances Inc. | Method for purifying rebaudioside C |
US10292412B2 (en) * | 2012-02-15 | 2019-05-21 | Kraft Foods Global Brands Llc | High solubility natural sweetener compositions |
WO2013158928A2 (en) | 2012-04-18 | 2013-10-24 | Elcelyx Therapeutics, Inc. | Chemosensory receptor ligand-based therapies |
US11013248B2 (en) | 2012-05-25 | 2021-05-25 | Kraft Foods Group Brands Llc | Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings |
CN110551646B (zh) | 2013-02-06 | 2024-04-26 | 埃沃尔瓦公司 | 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法 |
CA2900882A1 (en) | 2013-02-11 | 2014-08-14 | Evolva Sa | Efficient production of steviol glycosides in recombinants hosts |
SG11201700651RA (en) | 2014-08-11 | 2017-02-27 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
BR112017004712B1 (pt) | 2014-09-09 | 2021-11-03 | Evolva Sa | Hospedeiro recombinante que produz um precursor de glicosídeo de esteviol, métodos para produzir um precursor de glicosídeo de esteviol, um esteviol ou um ou mais glicosídeos de esteviol, cultura do dito hospedeiro e lisado da cultura do dito hospedeiro |
CN108337892B (zh) | 2015-01-30 | 2022-06-24 | 埃沃尔瓦公司 | 在重组宿主中生产甜菊醇糖苷 |
WO2016146711A1 (en) | 2015-03-16 | 2016-09-22 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
CN105037458B (zh) | 2015-07-23 | 2018-12-28 | 诸城市浩天药业有限公司 | 一种甜菊糖d苷晶型a、其制备方法及其应用 |
AU2016307066A1 (en) | 2015-08-07 | 2018-02-08 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
PL3422873T3 (pl) * | 2016-03-01 | 2024-06-10 | Wm. Wrigley Jr. Company | Długotrwałe formulacje słodzące |
US20190048356A1 (en) | 2016-03-11 | 2019-02-14 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
CA3020671A1 (en) | 2016-04-13 | 2017-10-19 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
US10815514B2 (en) | 2016-05-16 | 2020-10-27 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
WO2018083338A1 (en) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
WO2018211032A1 (en) | 2017-05-17 | 2018-11-22 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
BR112020009838A2 (pt) | 2017-12-05 | 2020-11-17 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
CN116606333A (zh) * | 2023-05-26 | 2023-08-18 | 东台市浩瑞生物科技有限公司 | 一种制备莱鲍迪苷c的工艺方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4361697A (en) | 1981-05-21 | 1982-11-30 | F. K. Suzuki International, Inc. | Extraction, separation and recovery of diterpene glycosides from Stevia rebaudiana plants |
US4353889A (en) * | 1981-06-11 | 1982-10-12 | Dynapol | Rebaudioside analogs |
JPS5945848A (ja) * | 1982-09-09 | 1984-03-14 | Morita Kagaku Kogyo Kk | 新天然甘味料の製造方法 |
US4612942A (en) | 1984-03-08 | 1986-09-23 | Stevia Company, Inc. | Flavor enhancing and modifying materials |
US4684534A (en) | 1985-02-19 | 1987-08-04 | Dynagram Corporation Of America | Quick-liquifying, chewable tablet |
US5011678A (en) | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
CA2185496A1 (en) * | 1996-09-13 | 1998-03-14 | John Donald Payzant | Method of extracting selected sweet glycosides from the stevia rebaudiana plant |
US6649186B1 (en) | 1996-09-20 | 2003-11-18 | Ethypharm | Effervescent granules and methods for their preparation |
US6368625B1 (en) | 1998-08-12 | 2002-04-09 | Cima Labs Inc. | Orally disintegrable tablet forming a viscous slurry |
US6060078A (en) | 1998-09-28 | 2000-05-09 | Sae Han Pharm Co., Ltd. | Chewable tablet and process for preparation thereof |
US6403142B1 (en) | 1998-12-11 | 2002-06-11 | Ralston Purina Company | Hypoallergenic pet food |
US6773716B2 (en) | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6187332B1 (en) | 1999-06-14 | 2001-02-13 | Wisconsin Alumni Research Foundation | Acidic buffered nasal spray |
US6316029B1 (en) | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
CN101312660B (zh) * | 2005-11-23 | 2013-07-17 | 可口可乐公司 | 供体重管理之高效甜味剂以及经彼甜化的组成物 |
MX2009007834A (es) * | 2007-01-22 | 2009-09-10 | Cargill Inc | Metodo para producir composiciones de rebaudiosido a purificado usando cristalizacion en solvente/ antisolvente. |
-
2010
- 2010-09-22 CA CA2773917A patent/CA2773917A1/en not_active Abandoned
- 2010-09-22 US US13/497,619 patent/US20120230922A1/en not_active Abandoned
- 2010-09-22 MX MX2012003489A patent/MX2012003489A/es not_active Application Discontinuation
- 2010-09-22 EP EP10760549A patent/EP2480097A1/en not_active Withdrawn
- 2010-09-22 AU AU2010298437A patent/AU2010298437B2/en not_active Ceased
- 2010-09-22 SG SG2012014270A patent/SG178920A1/en unknown
- 2010-09-22 BR BRBR112012006282-4A patent/BR112012006282A2/pt not_active IP Right Cessation
- 2010-09-22 CN CN201080042233.8A patent/CN102595932B/zh not_active Expired - Fee Related
- 2010-09-22 WO PCT/US2010/049763 patent/WO2011037959A1/en active Application Filing
-
2012
- 2012-03-01 ZA ZA2012/01542A patent/ZA201201542B/en unknown
-
2014
- 2014-10-31 US US14/530,056 patent/US20150064117A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
SG178920A1 (en) | 2012-04-27 |
WO2011037959A1 (en) | 2011-03-31 |
AU2010298437B2 (en) | 2014-06-19 |
CN102595932A (zh) | 2012-07-18 |
CA2773917A1 (en) | 2011-03-31 |
US20150064117A1 (en) | 2015-03-05 |
CN102595932B (zh) | 2014-07-16 |
ZA201201542B (en) | 2012-10-31 |
EP2480097A1 (en) | 2012-08-01 |
US20120230922A1 (en) | 2012-09-13 |
BR112012006282A2 (pt) | 2015-09-01 |
AU2010298437A1 (en) | 2012-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |