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MX2011011082A - Derivados de amida y amidina novedosos y usos de los mismos. - Google Patents

Derivados de amida y amidina novedosos y usos de los mismos.

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Publication number
MX2011011082A
MX2011011082A MX2011011082A MX2011011082A MX2011011082A MX 2011011082 A MX2011011082 A MX 2011011082A MX 2011011082 A MX2011011082 A MX 2011011082A MX 2011011082 A MX2011011082 A MX 2011011082A MX 2011011082 A MX2011011082 A MX 2011011082A
Authority
MX
Mexico
Prior art keywords
amidine derivatives
novel amide
type
disorders
obesity
Prior art date
Application number
MX2011011082A
Other languages
English (en)
Inventor
Jeffrey J Rohde
Sridhar Peddi
Meena V Patel
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2011011082A publication Critical patent/MX2011011082A/es

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Abstract

La presente invención se refiere a inhibidores de la enzima de deshidrogenasa 1 1-ß-hidroxiesteroide tipo 1 y su uso en tratamiento de diabetes tipo 2 dependiente de insulina, resistencia a insulina, obesidad, trastorno de lípidos, síndrome metabólico, trastornos del sistema nervioso central, y enfermedades y condiciones que están relacionadas con glucocorticoides excesivos.
MX2011011082A 2009-04-20 2010-04-20 Derivados de amida y amidina novedosos y usos de los mismos. MX2011011082A (es)

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PCT/US2010/031660 WO2010123838A2 (en) 2009-04-20 2010-04-20 Novel amide and amidine derivatives and uses thereof

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CN104672166A (zh) * 2015-02-10 2015-06-03 佛山市赛维斯医药科技有限公司 一种含脒结构的腈基苯基噻唑羧酸酰胺类双靶点抑制剂、其制备方法及用途
CN104672164A (zh) * 2015-02-10 2015-06-03 佛山市赛维斯医药科技有限公司 一类含苯基脒结构的sglt2/sglt1双靶点抑制剂、其制备方法及用途
CN104592148A (zh) * 2015-02-10 2015-05-06 佛山市赛维斯医药科技有限公司 一类含环丙基脒结构的硝基苯噻唑羧酸酰胺类化合物及用途
CN104628672A (zh) * 2015-02-10 2015-05-20 佛山市赛维斯医药科技有限公司 一类含苯基脒结构的烷氧苯基噻唑羧酸酰胺类化合物及用途
CN104628673A (zh) * 2015-02-10 2015-05-20 佛山市赛维斯医药科技有限公司 一类含叔丁基脒结构的腈基苯噻唑羧酸酰胺类化合物及用途
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CN104710382A (zh) * 2015-02-10 2015-06-17 佛山市赛维斯医药科技有限公司 一类含叔丁基脒结构的卤代苯基噻唑羧酸酰胺类化合物及用途
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