MX2011010673A - Formulaciones de nanoparticulas y usos de las mismas. - Google Patents
Formulaciones de nanoparticulas y usos de las mismas.Info
- Publication number
- MX2011010673A MX2011010673A MX2011010673A MX2011010673A MX2011010673A MX 2011010673 A MX2011010673 A MX 2011010673A MX 2011010673 A MX2011010673 A MX 2011010673A MX 2011010673 A MX2011010673 A MX 2011010673A MX 2011010673 A MX2011010673 A MX 2011010673A
- Authority
- MX
- Mexico
- Prior art keywords
- nanoparticle formulations
- uses therof
- therof
- compositions
- drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención provee composiciones que comprenden nanopartículas que comprenden: 1) un fármaco, tal como un derivado de fármaco hidrofóbico y 2) un portador de proteína. También se proveen métodos de tratamiento de enfermedades (tal como cánce) usando las composiciones, también como kits y unidades de dosificación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16854009P | 2009-04-10 | 2009-04-10 | |
PCT/US2010/030596 WO2010118365A1 (en) | 2009-04-10 | 2010-04-09 | Nanoparticle formulations and uses therof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011010673A true MX2011010673A (es) | 2012-02-21 |
Family
ID=42936607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011010673A MX2011010673A (es) | 2009-04-10 | 2010-04-09 | Formulaciones de nanoparticulas y usos de las mismas. |
Country Status (12)
Country | Link |
---|---|
US (3) | US20130195983A1 (es) |
EP (1) | EP2416650B1 (es) |
JP (2) | JP2012523433A (es) |
KR (1) | KR20120005505A (es) |
CN (1) | CN102458112A (es) |
AU (2) | AU2010233097B2 (es) |
BR (1) | BRPI1014160A2 (es) |
CA (1) | CA2758200A1 (es) |
ES (1) | ES2788298T3 (es) |
IL (1) | IL215665A0 (es) |
MX (1) | MX2011010673A (es) |
WO (1) | WO2010118365A1 (es) |
Families Citing this family (54)
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US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
ES2685436T3 (es) | 2002-12-09 | 2018-10-09 | Abraxis Bioscience, Llc | Composiciones y procedimientos para administración de agentes farmacológicos |
US8916546B2 (en) | 2003-08-29 | 2014-12-23 | Therapeutic Research Llc | Materials and methods for treatment and diagnosis of disorders associated with oxidative stress |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
NZ595313A (en) | 2005-02-18 | 2013-03-28 | Abraxis Bioscience Llc | The Use Of Nanoparticles Comprising Rapamycin Or Taxane In The Treatment Of Proliferative Diseases |
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EP3470071A1 (en) * | 2006-12-14 | 2019-04-17 | Abraxis BioScience, LLC | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
KR20150002886A (ko) * | 2007-03-07 | 2015-01-07 | 아브락시스 바이오사이언스, 엘엘씨 | 항암제로서 라파마이신 및 알부민을 포함하는 나노입자 |
EP2155188B1 (en) * | 2007-06-01 | 2013-10-09 | Abraxis BioScience, LLC | Methods and compositions for treating recurrent cancer |
JP5781500B2 (ja) | 2009-04-15 | 2015-09-24 | アブラクシス バイオサイエンス, エルエルシー | プリオンを含まないナノ粒子組成物および方法 |
LT2552438T (lt) | 2010-03-26 | 2016-09-26 | Abraxis Bioscience, Llc | Hepatoceliulinės karcinomos gydymo būdai |
JP6242213B2 (ja) | 2010-03-29 | 2017-12-06 | アブラクシス バイオサイエンス, エルエルシー | 薬物送達および治療用薬剤の有効性を向上させる方法 |
HUE030207T2 (en) | 2010-03-29 | 2017-04-28 | Abraxis Bioscience Llc | Cancer Treatment Procedures |
RU2576609C2 (ru) | 2010-06-04 | 2016-03-10 | АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи | Способы лечение рака поджелудочной железы |
KR101970342B1 (ko) | 2011-04-28 | 2019-04-18 | 아브락시스 바이오사이언스, 엘엘씨 | 나노입자 조성물의 혈관내 전달 및 그의 용도 |
LT2707030T (lt) | 2011-05-09 | 2020-07-10 | Mayo Foundation For Medical Education And Research | Vėžio gydymas |
LT2790675T (lt) | 2011-12-14 | 2019-11-11 | Abraxis Bioscience Llc | Polimerinių užpildų panaudojimas dalelių liofilizacijai arba šaldymui |
EP2903610B1 (en) | 2012-10-01 | 2021-11-03 | Mayo Foundation For Medical Education And Research | Cancer treatments |
JP6423353B2 (ja) | 2012-11-09 | 2018-11-14 | ハズ トゥー,エルエルシー | 潰瘍性大腸炎の治療のための長期安定性を有する浣腸剤組成物 |
US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
US10744110B2 (en) | 2013-03-12 | 2020-08-18 | Abraxis Bioscience, Llc | Methods of treating lung cancer |
NZ630213A (en) | 2013-03-14 | 2017-05-26 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
WO2015038924A1 (en) * | 2013-09-12 | 2015-03-19 | Albert Einstein College Of Medicine Of Yeshiva University | Modified paramagnetic nanoparticles for targeted delivery of therapeutics and methods thereof |
KR101534929B1 (ko) | 2013-10-17 | 2015-07-07 | 현대자동차주식회사 | 차량용 다 부품 자동운반장치 |
CA2952424C (en) | 2014-06-16 | 2019-07-23 | Mayo Foundation For Medical Education And Research | Treating myelomas |
US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
CN104306339A (zh) * | 2014-10-22 | 2015-01-28 | 南京大学 | 一种载有胸苷酸合酶抑制剂的白蛋白纳米微球及其制法 |
CN105727303B (zh) * | 2014-12-12 | 2019-06-28 | 四川科伦药物研究院有限公司 | 一种高载卡巴他赛药物的白蛋白组合物及其制剂和制备方法 |
US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
KR102798594B1 (ko) | 2015-06-29 | 2025-04-18 | 아브락시스 바이오사이언스, 엘엘씨 | 상피양 세포 종양을 치료하는 방법 |
TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體-抗體組合物及其製造及使用方法 |
TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
BR112018011476B1 (pt) * | 2015-12-10 | 2022-04-12 | Dsm Ip Assets B.V. | Tabletes comprimidos compreendendo pelo menos uma partícula sólida de vitamina e seu uso |
US11571469B2 (en) | 2016-01-07 | 2023-02-07 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon wherein the cancer cells are HLA negative or have reduced HLA expression |
AU2017207304B2 (en) | 2016-01-11 | 2022-05-26 | Epicentrx, Inc. | Compositions and methods for intravenous administration of 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone |
US11351254B2 (en) | 2016-02-12 | 2022-06-07 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
CA3018341A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
WO2017165439A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
KR102462041B1 (ko) | 2016-09-01 | 2022-11-02 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 암 치료용 담체-pd-l1 결합제 조성물 |
KR20190053203A (ko) | 2016-09-01 | 2019-05-17 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | T-세포 암을 표적화하는 방법 및 조성물 |
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KR20230011473A (ko) | 2016-09-06 | 2023-01-20 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | Pd-l1 발현 암의 치료 방법 |
WO2018048815A1 (en) | 2016-09-06 | 2018-03-15 | Nantibodyfc, Llc | Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins |
WO2018195416A1 (en) | 2017-04-21 | 2018-10-25 | Mayo Foundation For Medical Education And Research | Polypeptide-antibody complexes and uses thereof |
WO2019010447A1 (en) * | 2017-07-07 | 2019-01-10 | Epicentrx, Inc. | COMPOSITIONS FOR PARENTERAL ADMINISTRATION OF THERAPEUTIC AGENTS |
US11510901B2 (en) | 2018-01-08 | 2022-11-29 | Epicentrx, Inc. | Methods and compositions utilizing RRx-001 combination therapy for radioprotection |
AU2019239953B2 (en) | 2018-03-20 | 2025-01-02 | Abraxis Bioscience, Llc | Methods of treating central nervous system disorders via administration of nanoparticles of an mtor inhibitor and an albumin |
WO2020023549A1 (en) * | 2018-07-24 | 2020-01-30 | January Therapeutics, Inc. | Nanoparticle compositions |
CA3158764A1 (en) | 2019-10-28 | 2021-05-06 | Abraxis Bioscience, Llc | Pharmaceutical compositions of albumin and rapamycin |
EP4054550A4 (en) * | 2019-11-05 | 2024-01-17 | Luminus Biosciences Inc. | NANOPARTICLES WITH PRODRUGS STABILIZED BY ALBUMIN FOR THE TREATMENT OF CANCER AND OTHER DISEASES |
JP2021093979A (ja) * | 2019-12-18 | 2021-06-24 | 太陽化学株式会社 | 難水溶性物質含有組成物 |
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US6749868B1 (en) * | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US5558071A (en) * | 1994-03-07 | 1996-09-24 | Combustion Electromagnetics, Inc. | Ignition system power converter and controller |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US8137684B2 (en) | 1996-10-01 | 2012-03-20 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
KR100789008B1 (ko) * | 1997-06-27 | 2007-12-26 | 아브락시스 바이오사이언스 인크. | 신규 약물 제제 |
IL134830A0 (en) * | 2000-03-01 | 2001-05-20 | Chay 13 Medical Res Group N V | Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them |
JP2003526671A (ja) * | 2000-03-14 | 2003-09-09 | レストラゲン,インコーポレイテッド | 幽門洞−十二指腸運動性に対するグルカゴン様ペプチド‐1(7−36)の作用 |
ES2685436T3 (es) * | 2002-12-09 | 2018-10-09 | Abraxis Bioscience, Llc | Composiciones y procedimientos para administración de agentes farmacológicos |
CN1925874B (zh) * | 2002-12-09 | 2014-12-17 | 阿布拉西斯生物科学有限责任公司 | 组合物和传递药剂的方法 |
EP2896412A1 (en) * | 2005-02-18 | 2015-07-22 | Abraxis BioScience, LLC | Drugs with improved hydrophobicity for incorporation in medical devices |
JP5368093B2 (ja) * | 2005-08-31 | 2013-12-18 | アブラクシス バイオサイエンス, エルエルシー | 増大した安定性を有する難水溶性薬剤の組成物および調製の方法 |
MX339603B (es) * | 2006-09-25 | 2016-05-31 | Archer-Daniels-Midland Company | Polisacaridos carboxialquilados superabsorbentes con tratamiento de la superficie y procedimientos para producir los mismos. |
US20130084243A1 (en) * | 2010-01-27 | 2013-04-04 | Liliane Goetsch | Igf-1r specific antibodies useful in the detection and diagnosis of cellular proliferative disorders |
CA2735899A1 (en) * | 2008-09-25 | 2010-04-01 | Cephalon, Inc. | Liquid formulations of bendamustine |
US20110028412A1 (en) * | 2009-08-03 | 2011-02-03 | Cappellos, Inc. | Herbal enhanced analgesic formulations |
-
2010
- 2010-04-09 JP JP2012504898A patent/JP2012523433A/ja active Pending
- 2010-04-09 WO PCT/US2010/030596 patent/WO2010118365A1/en active Application Filing
- 2010-04-09 MX MX2011010673A patent/MX2011010673A/es not_active Application Discontinuation
- 2010-04-09 US US13/263,723 patent/US20130195983A1/en not_active Abandoned
- 2010-04-09 ES ES10762524T patent/ES2788298T3/es active Active
- 2010-04-09 EP EP10762524.6A patent/EP2416650B1/en active Active
- 2010-04-09 BR BRPI1014160-0A patent/BRPI1014160A2/pt not_active IP Right Cessation
- 2010-04-09 AU AU2010233097A patent/AU2010233097B2/en active Active
- 2010-04-09 KR KR1020117026658A patent/KR20120005505A/ko not_active Ceased
- 2010-04-09 CN CN2010800259726A patent/CN102458112A/zh active Pending
- 2010-04-09 CA CA2758200A patent/CA2758200A1/en not_active Abandoned
-
2011
- 2011-10-10 IL IL215665A patent/IL215665A0/en unknown
-
2013
- 2013-02-28 US US13/781,479 patent/US20140080901A1/en not_active Abandoned
-
2016
- 2016-07-07 AU AU2016204693A patent/AU2016204693A1/en not_active Abandoned
- 2016-11-29 US US15/364,189 patent/US20170172975A1/en not_active Abandoned
-
2017
- 2017-03-29 JP JP2017065384A patent/JP2017114913A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2010118365A1 (en) | 2010-10-14 |
AU2010233097A1 (en) | 2011-11-24 |
JP2017114913A (ja) | 2017-06-29 |
ES2788298T3 (es) | 2020-10-21 |
US20130195983A1 (en) | 2013-08-01 |
KR20120005505A (ko) | 2012-01-16 |
CN102458112A (zh) | 2012-05-16 |
EP2416650B1 (en) | 2020-02-26 |
AU2010233097B2 (en) | 2016-04-07 |
AU2016204693A1 (en) | 2016-07-28 |
IL215665A0 (en) | 2012-01-31 |
JP2012523433A (ja) | 2012-10-04 |
BRPI1014160A2 (pt) | 2015-08-25 |
US20140080901A1 (en) | 2014-03-20 |
US20170172975A1 (en) | 2017-06-22 |
CA2758200A1 (en) | 2010-10-14 |
EP2416650A4 (en) | 2014-01-01 |
EP2416650A1 (en) | 2012-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |