MX2011009258A - Emulsiones aceite-en-agua cationicas conteniendo prostaglandinas y usos de las mismas. - Google Patents
Emulsiones aceite-en-agua cationicas conteniendo prostaglandinas y usos de las mismas.Info
- Publication number
- MX2011009258A MX2011009258A MX2011009258A MX2011009258A MX2011009258A MX 2011009258 A MX2011009258 A MX 2011009258A MX 2011009258 A MX2011009258 A MX 2011009258A MX 2011009258 A MX2011009258 A MX 2011009258A MX 2011009258 A MX2011009258 A MX 2011009258A
- Authority
- MX
- Mexico
- Prior art keywords
- cationic oil
- water emulsions
- oil
- emulsions containing
- water
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 4
- 125000002091 cationic group Chemical group 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000839 emulsion Substances 0.000 title abstract 2
- 229940094443 oxytocics prostaglandins Drugs 0.000 title abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010048462 Growth of eyelashes Diseases 0.000 abstract 1
- 201000009495 Hypotrichosis Diseases 0.000 abstract 1
- 206010030043 Ocular hypertension Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000000720 eyelash Anatomy 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
La presente invención se refiere a una emulsión catiónica aceite- en-agua coloidal que comprende: - una prostaglandina, - un aceite teniendo un valor de yodo = 2, - uno o más surfactantes incluyendo al menos un compuesto de amonio cuaternario, - agua, en donde la proporción de masa de prostaglandina/suma total de surfactantes está comprendida entre 0.5 y 5. La presente invención también pertenece al uso de dichas emulsiones catiónicas aceite-en-agua para intensificar la estabilidad de dichas prostaglandinas, para el tratamiento e hipertensión ocular y/o glaucoma, para promover el crecimiento de pestañas y/o para tratar hipotricosis de pestañas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15735509P | 2009-03-04 | 2009-03-04 | |
| EP09305202A EP2228057A1 (en) | 2009-03-04 | 2009-03-04 | Cationic oil-in-water emulsions containing prostaglandins and uses thereof |
| PCT/EP2010/052741 WO2010100218A1 (en) | 2009-03-04 | 2010-03-04 | Cationic oil-in-water emulsions containing prostaglandins and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011009258A true MX2011009258A (es) | 2011-09-27 |
Family
ID=40627247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011009258A MX2011009258A (es) | 2009-03-04 | 2010-03-04 | Emulsiones aceite-en-agua cationicas conteniendo prostaglandinas y usos de las mismas. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20110313038A1 (es) |
| EP (2) | EP2228057A1 (es) |
| JP (1) | JP5722803B2 (es) |
| KR (1) | KR101813211B1 (es) |
| CN (1) | CN102341094B (es) |
| AU (1) | AU2010220322B2 (es) |
| CA (1) | CA2754157C (es) |
| ES (1) | ES2453472T3 (es) |
| IL (1) | IL214507A (es) |
| MX (1) | MX2011009258A (es) |
| WO (1) | WO2010100218A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004017477D1 (de) * | 2004-11-09 | 2008-12-11 | Novagali Pharma Sa | Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential |
| EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
| EP2389939A1 (en) * | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
| ES2616089T3 (es) | 2010-09-21 | 2017-06-09 | S & V Technologies Gmbh | Composición cosmética |
| JP6082158B2 (ja) * | 2013-03-14 | 2017-02-15 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ビマトプロストを含む局所用組成物及びそれを用いた育毛の刺激方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004017477D1 (de) * | 2004-11-09 | 2008-12-11 | Novagali Pharma Sa | Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential |
| WO2006050838A2 (en) * | 2004-11-09 | 2006-05-18 | Novagali Pharma Sa | Ophthalmic oil-in-water type emulsion with stable positive zeta potential |
| ES2351358T3 (es) * | 2005-10-10 | 2011-02-03 | Novagali Pharma S.A. | Emulsiones oftálmicas que contienen prostaglandinas. |
| EP2789339A1 (en) * | 2006-03-13 | 2014-10-15 | R-Tech Ueno, Ltd. | Aqueous composition comprising 15-keto-prostaglandin |
| WO2008035246A2 (en) * | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
| WO2008074885A2 (en) | 2006-12-21 | 2008-06-26 | Novagali Pharma Sa | Process for manufacturing ophthalmic oil-in-water emulsions |
| US20090169629A1 (en) * | 2008-01-02 | 2009-07-02 | Novagali Pharma Sa | Micellar compositions with ophthalmic applications |
-
2009
- 2009-03-04 EP EP09305202A patent/EP2228057A1/en not_active Withdrawn
-
2010
- 2010-03-04 US US13/203,754 patent/US20110313038A1/en not_active Abandoned
- 2010-03-04 EP EP10706647.4A patent/EP2403477B8/en active Active
- 2010-03-04 AU AU2010220322A patent/AU2010220322B2/en active Active
- 2010-03-04 MX MX2011009258A patent/MX2011009258A/es active IP Right Grant
- 2010-03-04 CN CN201080010329.6A patent/CN102341094B/zh active Active
- 2010-03-04 JP JP2011552444A patent/JP5722803B2/ja active Active
- 2010-03-04 CA CA2754157A patent/CA2754157C/en active Active
- 2010-03-04 KR KR1020117020761A patent/KR101813211B1/ko active Active
- 2010-03-04 WO PCT/EP2010/052741 patent/WO2010100218A1/en active Application Filing
- 2010-03-04 ES ES10706647.4T patent/ES2453472T3/es active Active
-
2011
- 2011-08-08 IL IL214507A patent/IL214507A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010100218A1 (en) | 2010-09-10 |
| CN102341094B (zh) | 2014-09-03 |
| EP2403477B1 (en) | 2014-01-15 |
| CN102341094A (zh) | 2012-02-01 |
| ES2453472T3 (es) | 2014-04-07 |
| AU2010220322B2 (en) | 2015-08-27 |
| JP2012519665A (ja) | 2012-08-30 |
| CA2754157A1 (en) | 2010-09-10 |
| AU2010220322A1 (en) | 2011-09-01 |
| IL214507A (en) | 2015-11-30 |
| HK1166609A1 (en) | 2012-11-02 |
| JP5722803B2 (ja) | 2015-05-27 |
| US20110313038A1 (en) | 2011-12-22 |
| EP2403477A1 (en) | 2012-01-11 |
| EP2403477B8 (en) | 2014-02-26 |
| KR20120010225A (ko) | 2012-02-02 |
| CA2754157C (en) | 2017-06-06 |
| KR101813211B1 (ko) | 2017-12-29 |
| EP2228057A1 (en) | 2010-09-15 |
| IL214507A0 (en) | 2011-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| HC | Change of company name or juridical status |
Owner name: BASF SE |