[go: up one dir, main page]

MX2011008621A - Proceso para la purificacion de lipopeptidos. - Google Patents

Proceso para la purificacion de lipopeptidos.

Info

Publication number
MX2011008621A
MX2011008621A MX2011008621A MX2011008621A MX2011008621A MX 2011008621 A MX2011008621 A MX 2011008621A MX 2011008621 A MX2011008621 A MX 2011008621A MX 2011008621 A MX2011008621 A MX 2011008621A MX 2011008621 A MX2011008621 A MX 2011008621A
Authority
MX
Mexico
Prior art keywords
purifying
lipopeptides
purifying lipopeptides
provides
relates
Prior art date
Application number
MX2011008621A
Other languages
English (en)
Inventor
Martin Maensson
Eli Karin Dale
Sissel Hauge
Kjersti Aastorp Hirth
Dennis Brian Hansen
Carsten Overballe-Petersen
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42116034&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011008621(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of MX2011008621A publication Critical patent/MX2011008621A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un proceso para la purificación de lipopéptidos. Más particularmente, la invención provee un método mejorado para la purificación de daptomicina.
MX2011008621A 2009-02-19 2010-02-19 Proceso para la purificacion de lipopeptidos. MX2011008621A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15366009P 2009-02-19 2009-02-19
PCT/NO2010/000066 WO2010095953A1 (en) 2009-02-19 2010-02-19 Process for purifying lipopeptides

Publications (1)

Publication Number Publication Date
MX2011008621A true MX2011008621A (es) 2011-09-15

Family

ID=42116034

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008621A MX2011008621A (es) 2009-02-19 2010-02-19 Proceso para la purificacion de lipopeptidos.

Country Status (21)

Country Link
US (1) US9150894B2 (es)
EP (1) EP2398817B2 (es)
JP (1) JP5752609B2 (es)
KR (1) KR101666144B1 (es)
CN (1) CN102325785B (es)
AU (1) AU2010216475B2 (es)
BR (1) BRPI1008300B1 (es)
CA (1) CA2748932C (es)
DK (1) DK2398817T4 (es)
ES (1) ES2543457T5 (es)
HR (1) HRP20150761T4 (es)
HU (1) HUE026818T2 (es)
IL (1) IL214374A (es)
MX (1) MX2011008621A (es)
PL (1) PL2398817T5 (es)
PT (1) PT2398817E (es)
RU (1) RU2526391C2 (es)
SI (1) SI2398817T2 (es)
UA (1) UA105785C2 (es)
WO (1) WO2010095953A1 (es)
ZA (1) ZA201104848B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2748932C (en) 2009-02-19 2019-11-19 Martin Mansson Process for purifying lipopeptides
CN102690329B (zh) * 2011-03-25 2014-06-04 杭州九源基因工程有限公司 一种戈舍瑞林多肽的纯化生产方法
CN102875652A (zh) * 2011-07-13 2013-01-16 北大方正集团有限公司 一种分离纯化达托霉素的方法
CN103159829B (zh) * 2011-12-08 2014-11-05 北大方正集团有限公司 达托霉素的提取方法
CN102675426B (zh) * 2012-04-26 2013-12-11 杭州华东医药集团生物工程研究所有限公司 一种达托霉素的提取纯化方法
CN102924572B (zh) * 2012-11-12 2014-12-03 华北制药集团新药研究开发有限责任公司 一种高纯度达托霉素的制备方法
CN104387444B (zh) * 2014-11-13 2017-12-08 北大医药重庆大新药业股份有限公司 一种达托霉素杂质rs‑2高纯度样品的制备方法
JP6845139B2 (ja) * 2014-12-15 2021-03-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 粗製溶液からの標的分子捕捉
CN105001305A (zh) * 2015-04-29 2015-10-28 利穗科技(苏州)有限公司 利用层析技术提取高纯度达托霉素的方法
CN105481950B (zh) * 2016-01-28 2019-01-04 丽珠集团福州福兴医药有限公司 一种达托霉素提取方法
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN108250270A (zh) * 2016-12-29 2018-07-06 天津领世生物科技开发有限公司 一种从发酵液中富集提取达托霉素的方法
CN112979756B (zh) * 2019-12-13 2023-01-03 浙江昌海制药有限公司 达托霉素的提纯方法
CN113004373B (zh) * 2019-12-19 2024-08-13 鲁南制药集团股份有限公司 一种达托霉素的纯化方法
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения
CN113340691B (zh) * 2021-06-05 2023-12-12 清华大学 一种提取海洋沉积物中不同赋存形态磷的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
US4667016A (en) 1985-06-20 1987-05-19 Kirin-Amgen, Inc. Erythropoietin purification
CA1315229C (en) 1987-06-10 1993-03-30 Patrick J. Baker Chromatographic purification process
US4874843A (en) 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
JP2661790B2 (ja) * 1990-11-27 1997-10-08 電気化学工業株式会社 入尿トリプシンインヒビターの精製方法
IL110669A (en) * 1993-08-17 2008-11-26 Kirin Amgen Inc Erythropoietin analogs
US5650496A (en) * 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
ES2377931T5 (es) 2000-12-18 2015-11-04 Cubist Pharmaceuticals, Inc. Métodos para preparar lipopéptidos purificados
US8969532B2 (en) * 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
WO2009144739A1 (en) * 2008-05-26 2009-12-03 Biocon Limited Amorphous daptomycin and a method of purification thereof
CA2748932C (en) 2009-02-19 2019-11-19 Martin Mansson Process for purifying lipopeptides
CN101899094B (zh) * 2009-06-01 2012-11-21 安徽丰原发酵技术工程研究有限公司 一种高纯达托霉素的制备方法

Also Published As

Publication number Publication date
IL214374A (en) 2017-03-30
BRPI1008300A8 (pt) 2021-05-11
EP2398817B2 (en) 2021-06-23
ES2543457T3 (es) 2015-08-19
UA105785C2 (uk) 2014-06-25
WO2010095953A1 (en) 2010-08-26
CA2748932A1 (en) 2010-08-26
BRPI1008300B1 (pt) 2021-07-13
RU2526391C2 (ru) 2014-08-20
BRPI1008300A2 (pt) 2016-03-15
HRP20150761T4 (hr) 2021-08-06
KR20110134884A (ko) 2011-12-15
CA2748932C (en) 2019-11-19
DK2398817T4 (da) 2021-08-23
PT2398817E (pt) 2015-08-28
RU2011137010A (ru) 2013-03-27
HRP20150761T1 (hr) 2015-08-14
CN102325785B (zh) 2015-01-21
IL214374A0 (en) 2011-09-27
EP2398817B1 (en) 2015-04-29
HUE026818T2 (en) 2016-07-28
US20100228006A1 (en) 2010-09-09
SI2398817T2 (sl) 2021-09-30
EP2398817A1 (en) 2011-12-28
DK2398817T3 (en) 2015-07-27
CN102325785A (zh) 2012-01-18
ZA201104848B (en) 2012-10-31
US9150894B2 (en) 2015-10-06
PL2398817T5 (pl) 2021-10-04
SI2398817T1 (sl) 2015-08-31
AU2010216475A1 (en) 2011-08-11
ES2543457T5 (es) 2021-12-22
PL2398817T3 (pl) 2015-10-30
KR101666144B1 (ko) 2016-10-13
AU2010216475B2 (en) 2015-07-09
JP2012518034A (ja) 2012-08-09
JP5752609B2 (ja) 2015-07-22

Similar Documents

Publication Publication Date Title
MX2011008621A (es) Proceso para la purificacion de lipopeptidos.
GB201103836D0 (en) Conjugation process
SI2504334T1 (sl) Postopek čiščenja (4,6-diamino-2-(1-(2-fluorobenzil)-1H-pirazolo-(3,4-b)piridin-3-il)piri midin-5-il)metilkarbamata
MX2013001045A (es) Organoide hepatico, sus usos y metodo de cultivo para obtenerlos.
WO2011019986A3 (en) Processes for preparing pemetrexed
MX2010009003A (es) Ciclohexanodimetanamina por aminacion directa de ciclohexanodimetanol.
IN2012DN02707A (es)
MX2011012558A (es) Producto con materiales de soporte biorreabsorbibles y envase.
MY163339A (en) A method of producing ingenol-3-angelate
MY159186A (en) Method for preparing small crystal ssz-32
MY150292A (en) Process for the preparation of triamides from ammonia and amido-dichlorides
IN2011CH01927A (es)
MX363617B (es) Metodo para la purificacion de compuestos de difosfitos organicos.
WO2010093182A3 (ko) Ｌ-아미노산 생산용 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
TW201129620A (en) New formaldehyde scavengers
MY158910A (en) Surface modified silicic acid semi-gels
TW200833649A (en) Method for the preparation of hydroxyadamantanamine
UA106988C2 (uk) Спосіб одержання 1-бензил-3-гідроксиметил-1h-індазолу і його похідних та необхідні проміжні сполуки магнію
IN2012DN01929A (es)
MX2012010317A (es) ß-HIDROXIALQUILAMIDAS, METODO PARA SU PRODUCCION Y SU USO.
MX2012010443A (es) Proceso para la preparacion de 1-alquiltetrazoles 5-sustituidos.
MX2013006867A (es) Procedimiento para la preparacion de sales de cis-1-amonio-4-alcoxiciclohexanocarbonitrilo.
PH12014501327A1 (en) Processes for making magnolol analogs
MX2010001962A (es) Procedimiento para preparar 4-aminobut-2-enolidos.
MX2012003888A (es) Semigeles de acido silicico de superficie modificada.

Legal Events

Date Code Title Description
FG Grant or registration