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MX2011007589A - Tratamiento de un cancer usando una combinacion de bendamustine y un anticuerpo anti-cd20. - Google Patents

Tratamiento de un cancer usando una combinacion de bendamustine y un anticuerpo anti-cd20.

Info

Publication number
MX2011007589A
MX2011007589A MX2011007589A MX2011007589A MX2011007589A MX 2011007589 A MX2011007589 A MX 2011007589A MX 2011007589 A MX2011007589 A MX 2011007589A MX 2011007589 A MX2011007589 A MX 2011007589A MX 2011007589 A MX2011007589 A MX 2011007589A
Authority
MX
Mexico
Prior art keywords
combination
bendamustine
antibody
cancer
treatment
Prior art date
Application number
MX2011007589A
Other languages
English (en)
Inventor
Cherry Teresa Thomas
Geoffrey Chan
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of MX2011007589A publication Critical patent/MX2011007589A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere generalmente al uso de bendamustine en combinación con un anticuerpo anti-CD20 para tratar el cáncer.
MX2011007589A 2009-01-16 2010-01-15 Tratamiento de un cancer usando una combinacion de bendamustine y un anticuerpo anti-cd20. MX2011007589A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14521009P 2009-01-16 2009-01-16
PCT/US2010/021123 WO2010083365A1 (en) 2009-01-16 2010-01-15 Treatment of a cancer using a combination of bendamustine and an anti-cd20 antibody

Publications (1)

Publication Number Publication Date
MX2011007589A true MX2011007589A (es) 2011-08-17

Family

ID=42340093

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007589A MX2011007589A (es) 2009-01-16 2010-01-15 Tratamiento de un cancer usando una combinacion de bendamustine y un anticuerpo anti-cd20.

Country Status (13)

Country Link
US (1) US20110274697A1 (es)
EP (1) EP2405937A4 (es)
JP (1) JP2012515217A (es)
KR (1) KR20110111303A (es)
CN (1) CN102355907A (es)
AU (1) AU2010204666A1 (es)
BR (1) BRPI1006829A2 (es)
CA (1) CA2749151A1 (es)
EA (1) EA201170940A1 (es)
IL (1) IL213794A0 (es)
MX (1) MX2011007589A (es)
SG (1) SG172792A1 (es)
WO (1) WO2010083365A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI409079B (zh) * 2009-08-14 2013-09-21 Roche Glycart Ag 非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法
US8822663B2 (en) 2010-08-06 2014-09-02 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
DE19177059T1 (de) 2010-10-01 2021-10-07 Modernatx, Inc. N1-methyl-pseudouracile enthältendes ribonucleinsäuren sowie ihre verwendungen
DE12722942T1 (de) 2011-03-31 2021-09-30 Modernatx, Inc. Freisetzung und formulierung von manipulierten nukleinsäuren
US20140255427A1 (en) * 2011-08-16 2014-09-11 Morphosys Ag Combination therapy with an anti - cd19 antibody and a nitrogen mustard
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
FR2980110A1 (fr) * 2011-09-20 2013-03-22 Lfb Biotechnologies Combinaison d'anticorps anti-cd20 et de bendamustine
KR20190099538A (ko) 2011-10-03 2019-08-27 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
CA2868393A1 (en) 2012-04-02 2013-10-10 Moderna Therapeutics, Inc. Modified polynucleotides for the production of oncology-related proteins and peptides
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
SI2922554T1 (sl) 2012-11-26 2022-06-30 Modernatx, Inc. Terminalno modificirana RNA
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
BR112016007255A2 (pt) 2013-10-03 2017-09-12 Moderna Therapeutics Inc polinucleotídeos que codificam receptor de lipoproteína de baixa densidade
WO2018013239A1 (en) * 2016-07-13 2018-01-18 Takeda Pharmaceutical Company Limited Combination of spleen tyrosine kinase inhibitors and other therapeutic agents
CN110540593B (zh) * 2018-05-29 2022-05-17 上海药明生物技术有限公司 新型的抗cd3/抗cd20双特异性抗体
US20210380710A1 (en) * 2018-05-29 2021-12-09 WuXi Biologics Ireland Limited A novel anti-cd3/anti-cd20 bispecific antibody
KR20210078505A (ko) 2018-10-16 2021-06-28 유에스 나노 푸드 앤 드럭 인코포레이티드 종양내 주사 제형
CA3169441A1 (en) 2020-04-13 2021-10-21 US Nano Food & Drug INC Basic chemotherapeutic intratumour injection formulation
US20230279138A1 (en) 2020-07-27 2023-09-07 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Novel bispecific anti-cd3/cd20 polypeptide complex formulation
GB202218493D0 (en) * 2022-12-08 2023-01-25 Oncopeptides Ab Novel therapeutic combinations
CN119584987A (zh) * 2023-03-01 2025-03-07 上海津曼特生物科技有限公司 包含cd20/cd47阻断双功能融合蛋白的联合用药物及其用途
WO2024263801A2 (en) * 2023-06-20 2024-12-26 Burzynski Stanislaw R Compositions comprising antineoplastons and methods of treating ovarian cancer
WO2024263798A1 (en) * 2023-06-20 2024-12-26 Burzynski Stanislaw R Compositions comprising antineoplastons and methods of treating prostate cancer
WO2024263804A2 (en) * 2023-06-20 2024-12-26 Burzynski Stanislaw R Compositions comprising antineoplastons and methods of treating kidney cancer
WO2024263813A2 (en) * 2023-06-21 2024-12-26 Burzynski Stanislaw R Compositions comprising antineoplastons and methods of treating colorectal cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1729203B (zh) * 2002-10-17 2014-02-19 根马布股份公司 抗cd20的人单克隆抗体
DK1684869T3 (da) * 2003-11-04 2011-10-31 Novartis Vaccines & Diagnostic Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme
JP5377968B2 (ja) * 2005-11-10 2013-12-25 トポターゲット ユーケー リミテッド 癌治療のために単独で用いるまたは化学療法薬と併用するヒストンデアセチラーゼ(hdac)阻害剤
US9382327B2 (en) * 2006-10-10 2016-07-05 Vaccinex, Inc. Anti-CD20 antibodies and methods of use
WO2009083009A2 (en) * 2008-01-03 2009-07-09 Genmab A/S Monoclonal antibodies against cd32b

Also Published As

Publication number Publication date
CA2749151A1 (en) 2010-07-22
CN102355907A (zh) 2012-02-15
EP2405937A1 (en) 2012-01-18
AU2010204666A1 (en) 2011-07-21
US20110274697A1 (en) 2011-11-10
EP2405937A4 (en) 2012-06-20
SG172792A1 (en) 2011-08-29
JP2012515217A (ja) 2012-07-05
EA201170940A1 (ru) 2012-02-28
KR20110111303A (ko) 2011-10-10
IL213794A0 (en) 2011-07-31
WO2010083365A1 (en) 2010-07-22
BRPI1006829A2 (pt) 2016-10-25

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