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MX2010005060A - Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados. - Google Patents

Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados.

Info

Publication number
MX2010005060A
MX2010005060A MX2010005060A MX2010005060A MX2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A
Authority
MX
Mexico
Prior art keywords
mapping
dna microarray
based identification
translocation breakpoints
microarray based
Prior art date
Application number
MX2010005060A
Other languages
English (en)
Inventor
Harvey A Greisman
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of MX2010005060A publication Critical patent/MX2010005060A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

La presente invención prove métodos para detector y mapear re-arreglos cromosomales asociados con varias enfermedades usando hibridización genómica comparativa. Se incluyen métodos para identificar socios de translocación de sitios genómicos conocidos y para determinar puntos de ruptura de translocación. Los métodos de la presente invención pueden también ser usados en la prognosis, diagnosis y determinación de predisposición a enfermedades que involucran rearreglos cromosomales tales como translocaciones.
MX2010005060A 2007-11-08 2008-11-10 Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados. MX2010005060A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98657607P 2007-11-08 2007-11-08
PCT/US2008/083014 WO2009062166A2 (en) 2007-11-08 2008-11-10 Dna microarray based identification and mapping of balanced translocation breakpoints

Publications (1)

Publication Number Publication Date
MX2010005060A true MX2010005060A (es) 2010-07-05

Family

ID=40626471

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005060A MX2010005060A (es) 2007-11-08 2008-11-10 Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados.

Country Status (10)

Country Link
US (1) US20110021371A1 (es)
EP (1) EP2217921A4 (es)
JP (1) JP5421278B2 (es)
KR (1) KR20100097139A (es)
CN (1) CN101918831B (es)
AU (1) AU2008323649A1 (es)
BR (1) BRPI0820272A2 (es)
CA (1) CA2704625A1 (es)
MX (1) MX2010005060A (es)
WO (1) WO2009062166A2 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2147981A1 (en) * 2008-07-25 2010-01-27 Biotype AG Kit and method for evaluating detection properties in amplification reactions
ITMI20091007A1 (it) 2009-06-09 2010-12-10 Giovanni Porta Metodo di monitoraggio e trattamento
WO2011038360A1 (en) 2009-09-25 2011-03-31 Signature Genomics Laboratories Llc Multiplex (+/-) stranded arrays and assays for detecting chromosomal abnormalities associated with cancer and other diseases
WO2012159069A1 (en) * 2011-05-19 2012-11-22 University Of Utah Research Foundation Methods and compostions for the detection of balanced reciprocal translocations/rearrangements
WO2013033169A1 (en) * 2011-08-31 2013-03-07 Sanofi Methods of identifying genomic translocations associated with cancer
FR3010530B1 (fr) * 2013-09-11 2015-10-09 Univ Rouen Methode de diagnostic des hemopathies malignes et kit associe
CN103704205B (zh) * 2014-01-15 2015-09-23 山东大学 一种含微量稀土的牛精液冷冻稀释液及其应用
US10443090B2 (en) 2014-11-25 2019-10-15 Electronics And Telecommunications Research Institute Method and apparatus for detecting translocation
KR20180030481A (ko) * 2015-05-29 2018-03-23 아르테르곤 에스.에이. 증진된 ｃｇｈ 분석을 위한 방법, 지지체 및 키트
CN105044168A (zh) * 2015-06-03 2015-11-11 福建医科大学 基于氟代核酸探针的双通道传感器检测急早幼粒PML/RARα基因序列的方法
GB202117415D0 (en) * 2019-05-08 2022-01-19 Oxford BioDynamics PLC Chromosome conformation markers of prostate cancer and lymphoma
CN112669902B (zh) * 2021-03-16 2021-06-04 北京贝瑞和康生物技术有限公司 检测基因组结构变异的方法、计算设备和存储介质

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US6251601B1 (en) * 1999-02-02 2001-06-26 Vysis, Inc. Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
US7585964B2 (en) * 2001-05-14 2009-09-08 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH)
US20050159378A1 (en) * 2001-05-18 2005-07-21 Sirna Therapeutics, Inc. RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
US7198897B2 (en) * 2001-12-19 2007-04-03 Brandeis University Late-PCR
US20030124539A1 (en) * 2001-12-21 2003-07-03 Affymetrix, Inc. A Corporation Organized Under The Laws Of The State Of Delaware High throughput resequencing and variation detection using high density microarrays
US20040097711A1 (en) * 2002-03-12 2004-05-20 Henry Yue Immunoglobulin superfamily proteins
US20050112689A1 (en) * 2003-04-04 2005-05-26 Robert Kincaid Systems and methods for statistically analyzing apparent CGH data anomalies and plotting same
AU2003901671A0 (en) * 2003-04-02 2003-05-01 The University Of Adelaide Comparative genomic hybridization
DE102005028381A1 (de) * 2005-06-20 2006-12-28 Wella Ag Produktabgabesystem zum Versprühen haarkerantinreduzierende oder oxidierende Wirkstoffe enthaltender Zusammensetzungen
DE102005031734A1 (de) * 2005-07-07 2007-01-18 GM Global Technology Operations, Inc., Detroit Verfahren zur Berechnung des Unterdruckes im Bremskraftverstärker eines Fahrzeugs mit Otto-Motor
GB0516797D0 (en) * 2005-08-16 2005-09-21 Oxford Gene Tech Ip Ltd CGH method
US8076074B2 (en) * 2005-11-29 2011-12-13 Quest Diagnostics Investments Incorporated Balanced translocation in comparative hybridization
US8058055B2 (en) * 2006-04-07 2011-11-15 Agilent Technologies, Inc. High resolution chromosomal mapping

Also Published As

Publication number Publication date
EP2217921A4 (en) 2011-07-06
CA2704625A1 (en) 2009-05-14
BRPI0820272A2 (pt) 2015-05-26
CN101918831B (zh) 2014-10-15
WO2009062166A2 (en) 2009-05-14
JP2011505122A (ja) 2011-02-24
KR20100097139A (ko) 2010-09-02
US20110021371A1 (en) 2011-01-27
WO2009062166A3 (en) 2009-12-30
EP2217921A2 (en) 2010-08-18
CN101918831A (zh) 2010-12-15
AU2008323649A1 (en) 2009-05-14
JP5421278B2 (ja) 2014-02-19

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