MX2009005739A - Derivado piperidinico utilizado para tratar enfermedades mediadas por el receptor 5 de quimiocina. - Google Patents
Derivado piperidinico utilizado para tratar enfermedades mediadas por el receptor 5 de quimiocina.Info
- Publication number
- MX2009005739A MX2009005739A MX2009005739A MX2009005739A MX2009005739A MX 2009005739 A MX2009005739 A MX 2009005739A MX 2009005739 A MX2009005739 A MX 2009005739A MX 2009005739 A MX2009005739 A MX 2009005739A MX 2009005739 A MX2009005739 A MX 2009005739A
- Authority
- MX
- Mexico
- Prior art keywords
- chemokine receptor
- mediated diseases
- derivative used
- piperidine derivative
- treating chemokine
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 102000009410 Chemokine receptor Human genes 0.000 title 1
- 108050000299 Chemokine receptor Proteins 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 title 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
La presente invención se refiere a 4-[3-(1,1-difluoroetil)-5-metil -4H-1,2,4-triazol-4-il]-1-{(1R,3R)-3-(3,5-difluorofenil)-1-metil- 3-[1-(metilsulfonil)piperidin-4-il]propil}piperidina fórmula (I): o a una sal farmacéuticamente aceptable de ésta, así como también a procesos para la preparación de este compuesto y a su uso en el tratamiento de enfermedades mediadas por CCR5.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86943606P | 2006-12-11 | 2006-12-11 | |
| PCT/GB2007/004706 WO2008071927A1 (en) | 2006-12-11 | 2007-12-10 | Piperidine derivative used for treating chemokine receptor 5 mediated diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009005739A true MX2009005739A (es) | 2009-06-08 |
Family
ID=39048005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009005739A MX2009005739A (es) | 2006-12-11 | 2007-12-10 | Derivado piperidinico utilizado para tratar enfermedades mediadas por el receptor 5 de quimiocina. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20100099708A1 (es) |
| EP (1) | EP2091946A1 (es) |
| JP (1) | JP2010512376A (es) |
| KR (1) | KR20090086588A (es) |
| CN (1) | CN101558060A (es) |
| AR (1) | AR064277A1 (es) |
| AU (1) | AU2007331316A1 (es) |
| BR (1) | BRPI0720291A2 (es) |
| CA (1) | CA2671460A1 (es) |
| CL (1) | CL2007003572A1 (es) |
| EC (1) | ECSP099381A (es) |
| IL (1) | IL198874A0 (es) |
| MX (1) | MX2009005739A (es) |
| NO (1) | NO20092475L (es) |
| PE (1) | PE20081449A1 (es) |
| RU (1) | RU2009119287A (es) |
| TW (1) | TW200831483A (es) |
| UY (1) | UY30770A1 (es) |
| WO (1) | WO2008071927A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200610761A (en) * | 2004-04-23 | 2006-04-01 | Astrazeneca Ab | Chemical compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200610761A (en) * | 2004-04-23 | 2006-04-01 | Astrazeneca Ab | Chemical compounds |
-
2007
- 2007-11-30 TW TW096145655A patent/TW200831483A/zh unknown
- 2007-12-10 BR BRPI0720291-1A patent/BRPI0720291A2/pt not_active Application Discontinuation
- 2007-12-10 WO PCT/GB2007/004706 patent/WO2008071927A1/en active Application Filing
- 2007-12-10 CL CL200703572A patent/CL2007003572A1/es unknown
- 2007-12-10 PE PE2007001756A patent/PE20081449A1/es not_active Application Discontinuation
- 2007-12-10 CN CNA2007800457941A patent/CN101558060A/zh active Pending
- 2007-12-10 US US12/518,489 patent/US20100099708A1/en not_active Abandoned
- 2007-12-10 UY UY30770A patent/UY30770A1/es unknown
- 2007-12-10 MX MX2009005739A patent/MX2009005739A/es unknown
- 2007-12-10 KR KR1020097011983A patent/KR20090086588A/ko not_active Withdrawn
- 2007-12-10 JP JP2009540842A patent/JP2010512376A/ja active Pending
- 2007-12-10 US US11/953,197 patent/US20080139612A1/en not_active Abandoned
- 2007-12-10 AU AU2007331316A patent/AU2007331316A1/en not_active Abandoned
- 2007-12-10 CA CA002671460A patent/CA2671460A1/en not_active Abandoned
- 2007-12-10 EP EP07848454A patent/EP2091946A1/en not_active Withdrawn
- 2007-12-10 RU RU2009119287/04A patent/RU2009119287A/ru not_active Application Discontinuation
- 2007-12-11 AR ARP070105534A patent/AR064277A1/es unknown
-
2009
- 2009-05-21 IL IL198874A patent/IL198874A0/en unknown
- 2009-06-03 EC EC2009009381A patent/ECSP099381A/es unknown
- 2009-06-30 NO NO20092475A patent/NO20092475L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20092475L (no) | 2009-09-09 |
| UY30770A1 (es) | 2008-07-31 |
| RU2009119287A (ru) | 2011-01-20 |
| TW200831483A (en) | 2008-08-01 |
| US20100099708A1 (en) | 2010-04-22 |
| ECSP099381A (es) | 2009-07-31 |
| US20080139612A1 (en) | 2008-06-12 |
| KR20090086588A (ko) | 2009-08-13 |
| AR064277A1 (es) | 2009-03-25 |
| EP2091946A1 (en) | 2009-08-26 |
| JP2010512376A (ja) | 2010-04-22 |
| CA2671460A1 (en) | 2008-06-19 |
| PE20081449A1 (es) | 2008-12-07 |
| AU2007331316A1 (en) | 2008-06-19 |
| WO2008071927A1 (en) | 2008-06-19 |
| IL198874A0 (en) | 2010-02-17 |
| CL2007003572A1 (es) | 2008-08-22 |
| CN101558060A (zh) | 2009-10-14 |
| BRPI0720291A2 (pt) | 2014-02-04 |
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