MX156874A - Un procedimiento para la preparacion de un diesterasimetrico del acido 1,4-dihidro-2,6-dimetilpiridin-3,5-dicarboxilico - Google Patents

Un procedimiento para la preparacion de un diesterasimetrico del acido 1,4-dihidro-2,6-dimetilpiridin-3,5-dicarboxilico

Info

Publication number: MX156874A
Authority: MX; Mexico
Prior art keywords: dimetilpiridin; diesterasymmetric; dicarboxilico; dihidro; procedure
Prior art date: 1984-02-14

Application number

MX204305A

Other languages

English (en)

Inventor

Dante Nardi

Amedeo Leonardi

Gabriele Graziani

Giorgio Bianchi

Original Assignee

Recordati Chem Pharm

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-02-14

Filing date

1985-02-12

Publication date

1988-10-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10556581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX156874(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-02-12 Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm

1988-10-08 Publication of MX156874A publication Critical patent/MX156874A/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

MX204305A 1984-02-14 1985-02-12 Un procedimiento para la preparacion de un diesterasimetrico del acido 1,4-dihidro-2,6-dimetilpiridin-3,5-dicarboxilico MX156874A (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB848403866A GB8403866D0 (en)	1984-02-14	1984-02-14	Diphenylalkylaminoalkyl esters

Publications (1)

Publication Number	Publication Date
MX156874A true MX156874A (es)	1988-10-08

Family

ID=10556581

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX204305A MX156874A (es)	1984-02-14	1985-02-12	Un procedimiento para la preparacion de un diesterasimetrico del acido 1,4-dihidro-2,6-dimetilpiridin-3,5-dicarboxilico

Country Status (29)

Country	Link
US (3)	US4705797A (es)
EP (1)	EP0153016B1 (es)
JP (1)	JPS60199874A (es)
KR (1)	KR910005231B1 (es)
AR (1)	AR240804A1 (es)
AT (1)	ATE52772T1 (es)
AU (1)	AU570534B2 (es)
BR (1)	BR1101167A (es)
CA (1)	CA1277666C (es)
DE (2)	DE10199007I2 (es)
DK (1)	DK160985C (es)
DZ (1)	DZ748A1 (es)
EG (1)	EG17772A (es)
ES (1)	ES540385A0 (es)
FI (1)	FI83954C (es)
GB (1)	GB8403866D0 (es)
GR (1)	GR850363B (es)
HU (1)	HU194171B (es)
IE (1)	IE57715B1 (es)
IL (1)	IL74238A (es)
LU (1)	LU90069I2 (es)
MX (1)	MX156874A (es)
NL (1)	NL970025I2 (es)
NO (2)	NO166123C (es)
NZ (1)	NZ210866A (es)
PH (1)	PH20725A (es)
PT (1)	PT79963B (es)
SG (1)	SG48590G (es)
ZA (1)	ZA85656B (es)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU561213B2 (en) *	1983-06-02	1987-04-30	Teijin Limited	1, 4-dihydropyridine derivative
US4994476A (en) *	1984-10-31	1991-02-19	Bristol-Myers Company	Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
EP0220917B1 (en) *	1985-10-22	1991-01-30	Sanwa Kagaku Kenkyusho Co., Ltd.	1,4-dihydropyridine pharmaceutical derivatives and their salts, and the preparation thereof
DE3633496A1 (de) *	1986-10-02	1988-04-14	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
JPH02149563A (ja) *	1988-11-30	1990-06-08	Nisshin Flour Milling Co Ltd	２−ハロエトキシカルボニル基を含有する１，４−ジヒドロピリジン誘導体の製造法
US5912351A (en) *	1995-05-12	1999-06-15	Recordati, S.A. Chemical And Pharmaceutical Company	Anhydrous 1,4-Dihydropyridines and salts thereof
IT1274480B (it) *	1995-05-12	1997-07-17	Recordati Chem Pharm	Procedimento migliorato per la preparazione della lercanidipina cloridrato
IT1279529B1 (it) *	1995-05-12	1997-12-16	Recordati Chem Pharm	Procedimento di preparazione ed uso degli enantiomeri (s) di derivati 1,4-diidropiridinici per il trattamento dell'insufficienza cardiaca
IT1275532B (it) *	1995-07-14	1997-08-07	Recordati Chem Pharm	Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa
US5696139A (en) *	1995-05-12	1997-12-09	Recordati S.A., Chemical And Pharmaceutical Company	Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
US5851636A (en) *	1995-12-29	1998-12-22	Lantec Products, Inc.	Ceramic packing with channels for thermal and catalytic beds
RU2200315C2 (ru) *	2001-05-25	2003-03-10	Чалкин Станислав Филиппович	Устройство для анализа жидких сред люминесцентным методом
US6852737B2 (en) *	2001-08-06	2005-02-08	Recordati Ireland Limited	Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011727A1 (it) *	2001-08-06	2003-02-06	Recordati Ind Chimica E Farma	Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
ITMI20011726A1 (it) *	2001-08-06	2003-02-06	Recordati Ind Chimica E Farma	Forme polimorfe della lercanidipina cloridrato
GEP20074134B (en)	2002-08-19	2007-06-25	Pfizer Prod Inc	Combination therapy for hyperproliferative diseases
US20050101640A1 (en) *	2002-10-16	2005-05-12	Recordati Ireland Limited	Lisinopril/lercanidipine combination therapy
US20040147566A1 (en) *	2002-10-16	2004-07-29	Amedeo Leonardi	Lisinopril/lercanidipine combination therapy
AP2501A (en)	2003-05-30	2012-10-22	Ranbaxy Lab Ltd	Substituted pyrrole derivatives
WO2005107374A2 (en) *	2004-05-07	2005-11-17	Sun Pharmaceutical Industries Limited	A process for the preparation of 1,4-dihydropyridine-3,5-dicarboxylic acid derivative
US20060147520A1 (en) *	2004-07-26	2006-07-06	Curtis Ruegg	Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
TW200613275A (en) *	2004-08-24	2006-05-01	Recordati Ireland Ltd	Lercanidipine salts
US20060134212A1 (en) *	2004-09-02	2006-06-22	Forest Laboratories, Inc.	Lercanidipine immediate release compositions
US20060165789A1 (en) *	2004-09-09	2006-07-27	Forest Laboratories, Inc.	Lercanidipine modified release compositions
US20060165788A1 (en) *	2004-09-09	2006-07-27	Wattanaporn Abramowitz	Lercanidipine pH dependent pulsatile release compositions
KR100616276B1 (ko) *	2004-09-21	2006-08-28	일동제약주식회사	2,엔-디메틸-엔-(3,3-디페닐프로필)-1-아미노-2-프로판올의제조방법
TW200616681A (en) *	2004-10-05	2006-06-01	Recordati Ireland Ltd	Lercanidipine capsules
KR100651212B1 (ko) *	2004-10-27	2006-12-01	제일약품주식회사	무정형 레르카니디핀의 제조방법
IL165525A0 (en) *	2004-12-02	2006-01-15	Motivan Ltd	Intermediates and a process for the manufacturing for antihypertensive dihydropyridine derivative suitable for pharmaceutical compositions
AR053023A1 (es) *	2005-02-25	2007-04-18	Recordati Ireland Ltd	Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
AR052918A1 (es) *	2005-02-25	2007-04-11	Recordati Ireland Ltd	Clorhidrato de lercanidipina amorfo
KR100638171B1 (ko) *	2005-03-25	2006-10-26	건일제약 주식회사	2,ｎ-디메틸-ｎ-(3,3-디페닐프로필)-1-아미노-2-프로판올의제조방법
DE602005017199D1 (de) *	2005-06-15	2009-11-26	Hetero Drugs Ltd	Neues verfahren zur herstellung von lercanidipin
EP1940790B1 (en) *	2005-09-16	2015-09-02	Glenmark Pharmaceuticals Limited	Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof
WO2007054969A2 (en) *	2005-09-21	2007-05-18	Torrent Pharmaceuticals Limited	Process for the preparation of lercanidipine and amorphous form of lercanidipine hydrochloride
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
EP2351569B1 (en)	2005-10-26	2012-08-22	Asahi Kasei Pharma Corporation	Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
JP2009513660A (ja)	2005-10-26	2009-04-02	旭化成ファーマ株式会社	肺動脈性高血圧の治療用併用療法におけるファスジル
KR101329112B1 (ko)	2005-11-08	2013-11-14	랜박시 래보러터리스 리미티드	(3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US7919506B2 (en)	2006-03-10	2011-04-05	Pfizer Inc.	Dibenzyl amine compounds and derivatives
WO2007120135A1 (en) *	2006-04-17	2007-10-25	Forest Laboratories, Inc.	Lercanidipine immediate release composition
ATE415389T1 (de) *	2006-05-24	2008-12-15	Cf Pharma Ltd	Verfahren zur herstellung von lercanipidin
AU2007280407B2 (en) *	2006-08-04	2012-09-27	Recordati Ireland Limited	Process for preparing amorphous lercanidipine hydrochloride
US20080175872A1 (en) *	2006-09-28	2008-07-24	Osmotica Corp.	Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
ATE547394T1 (de)	2006-12-01	2012-03-15	Bristol Myers Squibb Co	N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
JP2010514753A (ja) *	2006-12-29	2010-05-06	ドンウシンテックカンパニーリミテッド	レルカニジピン塩酸塩の製造方法
KR100848935B1 (ko)	2007-05-16	2008-07-29	주식회사 대희화학	생체 촉매 효소를 이용한 광학 선택적 가수분해방법
EA027787B1 (ru)	2010-06-23	2017-09-29	Крка, Товарна Здравил, Д.Д., Ново Место	Пероральные лекарственные формы, содержащие лерканидипин и эналаприл и их фармацевтически приемлемые соли
WO2012037665A1 (en)	2010-09-24	2012-03-29	Oral Delivery Technology Ltd.	Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2444394A1 (en)	2010-10-21	2012-04-25	Alembic Pharmaceuticals Limited	Process for the preparation of amorphous form of lercanidipine HCI
EA023996B1 (ru)	2010-12-24	2016-08-31	КРКА, д.д., НОВО МЕСТО	Гомогенные фармацевтические пероральные лекарственные формы, содержащие лерканидипин и эналаприл или их фармацевтически приемлемые соли совместно с органической кислотой
WO2012123966A1 (en)	2011-03-04	2012-09-20	Arch Pharmalabs Limited	Process for the preparation of 4 -substituted -1, 4-dihydropyridines
KR101695582B1 (ko)	2013-04-17	2017-01-13	화이자 인코포레이티드	심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
MX2021008533A (es)	2019-01-18	2021-08-19	Astrazeneca Ab	Inhibidores de la pcsk9 y metodos de uso de los mismos.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3985758A (en) *	1973-02-20	1976-10-12	Yamanouchi Pharmaceutical Co., Ltd.	1,4-Dihydropyridine derivatives
JPS5762257A (en) *	1980-10-03	1982-04-15	Yoshitomi Pharmaceut Ind Ltd	1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
NZ201395A (en) *	1981-07-30	1987-02-20	Bayer Ag	Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3269219D1 (en) *	1981-11-17	1986-03-27	Fisons Plc	Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ATE50987T1 (de) *	1982-05-10	1990-03-15	Takeda Chemical Industries Ltd	Dihydropyridinderivate, deren herstellung und verwendung.
AU561213B2 (en) *	1983-06-02	1987-04-30	Teijin Limited	1, 4-dihydropyridine derivative
NO854021L (no) *	1984-10-26	1986-04-28	Bayer Ag	1,4-dihydropyridin-hydroksyaminer og fremgangsmaate til fremstilling derav.
GB8503424D0 (en) *	1985-02-11	1985-03-13	Ici Plc	Heterocyclic derivatives

1984
- 1984-02-14 GB GB848403866A patent/GB8403866D0/en active Pending
1985
- 1985-01-17 NZ NZ210866A patent/NZ210866A/xx unknown
- 1985-01-21 DE DE2001199007 patent/DE10199007I2/de active Active
- 1985-01-21 AT AT85300384T patent/ATE52772T1/de active
- 1985-01-21 EP EP85300384A patent/EP0153016B1/en not_active Expired - Lifetime
- 1985-01-21 DE DE8585300384T patent/DE3577703D1/de not_active Expired - Lifetime
- 1985-01-28 ZA ZA85656A patent/ZA85656B/xx unknown
- 1985-02-04 IL IL74238A patent/IL74238A/xx not_active IP Right Cessation
- 1985-02-06 IE IE280/85A patent/IE57715B1/en not_active IP Right Cessation
- 1985-02-08 FI FI850535A patent/FI83954C/fi not_active IP Right Cessation
- 1985-02-11 EG EG83/85A patent/EG17772A/xx active
- 1985-02-11 GR GR850363A patent/GR850363B/el not_active IP Right Cessation
- 1985-02-11 AR AR299475A patent/AR240804A1/es active
- 1985-02-11 CA CA000474009A patent/CA1277666C/en not_active Expired - Lifetime
- 1985-02-12 DK DK063085A patent/DK160985C/da not_active IP Right Cessation
- 1985-02-12 NO NO850521A patent/NO166123C/no unknown
- 1985-02-12 MX MX204305A patent/MX156874A/es unknown
- 1985-02-13 DZ DZ850035A patent/DZ748A1/fr active
- 1985-02-13 ES ES540385A patent/ES540385A0/es active Granted
- 1985-02-13 AU AU38689/85A patent/AU570534B2/en not_active Expired
- 1985-02-13 KR KR1019850000888A patent/KR910005231B1/ko not_active Expired
- 1985-02-13 PT PT79963A patent/PT79963B/pt unknown
- 1985-02-14 PH PH31860A patent/PH20725A/en unknown
- 1985-02-14 HU HU85554A patent/HU194171B/hu unknown
- 1985-02-14 JP JP60027527A patent/JPS60199874A/ja active Granted
- 1985-02-14 US US06/701,672 patent/US4705797A/en not_active Expired - Lifetime
1987
- 1987-08-19 US US07/086,739 patent/US4772621A/en not_active Expired - Lifetime
1988
- 1988-06-28 US US07/212,472 patent/US4968832A/en not_active Expired - Lifetime
1990
- 1990-07-02 SG SG485/90A patent/SG48590G/en unknown
1997
- 1997-05-14 BR BR1101167-0A patent/BR1101167A/pt active IP Right Grant
- 1997-05-28 LU LU90069C patent/LU90069I2/fr unknown
- 1997-07-11 NL NL970025C patent/NL970025I2/nl unknown
2000
- 2000-10-17 NO NO2000011C patent/NO2000011I1/no unknown

Also Published As

Publication number	Publication date
HU194171B (en)	1988-01-28
PT79963B (en)	1986-11-10
DK63085A (da)	1985-08-15
SG48590G (en)	1990-08-17
EP0153016A2 (en)	1985-08-28
DK160985B (da)	1991-05-13
CA1277666C (en)	1990-12-11
DE10199007I1 (de)	2001-04-12
NL970025I2 (nl)	1998-01-05
AU3868985A (en)	1985-09-12
NO2000011I1 (no)	2000-10-17
ATE52772T1 (de)	1990-06-15
US4705797A (en)	1987-11-10
JPH0517908B2 (es)	1993-03-10
DZ748A1 (fr)	2004-09-13
FI83954B (fi)	1991-06-14
AR240804A2 (es)	1991-02-28
PT79963A (en)	1985-03-01
NL970025I1 (nl)	1997-09-01
DE3577703D1 (de)	1990-06-21
DK63085D0 (da)	1985-02-12
KR850005826A (ko)	1985-09-26
GR850363B (es)	1986-02-06
FI850535A0 (fi)	1985-02-08
NZ210866A (en)	1988-07-28
EP0153016A3 (en)	1985-10-02
KR910005231B1 (ko)	1991-07-24
NO166123C (no)	1991-06-05
IL74238A0 (en)	1985-05-31
IL74238A (en)	1988-07-31
GB8403866D0 (en)	1984-03-21
ZA85656B (en)	1985-08-28
JPS60199874A (ja)	1985-10-09
FI83954C (fi)	1991-09-25
PH20725A (en)	1987-03-30
ES8602664A1 (es)	1985-11-16
EG17772A (en)	1991-08-30
HUT37399A (en)	1985-12-28
NO166123B (no)	1991-02-25
IE850280L (en)	1985-08-14
IE57715B1 (en)	1993-03-10
FI850535L (fi)	1985-08-15
AU570534B2 (en)	1988-03-17
LU90069I2 (fr)	1997-07-23
US4968832A (en)	1990-11-06
EP0153016B1 (en)	1990-05-16
DE10199007I2 (de)	2003-01-09
BR1101167A (pt)	2004-08-17
ES540385A0 (es)	1985-11-16
DK160985C (da)	1991-11-04
AR240804A1 (es)	1991-02-28
US4772621A (en)	1988-09-20
NO850521L (no)	1985-08-15

Publication	Publication Date	Title
MX156874A (es)	1988-10-08	Un procedimiento para la preparacion de un diesterasimetrico del acido 1,4-dihidro-2,6-dimetilpiridin-3,5-dicarboxilico
ES552048A0 (es)	1987-09-01	Un procedimiento para la preparacion de esteres del acido 1,4, dihidro-3,5-piridincarboxilico.
ES544439A0 (es)	1986-02-01	Procedimiento para la preparacion de acidos a,w -dicarboxi- licos
ES549359A0 (es)	1986-12-01	Un procedimiento para la preparacion de nuevos derivados del acido (5-amino-2-hidroxi)benzoico.
ES521337A0 (es)	1984-05-16	Un procedimiento para la preparacion de derivados del acido fenoxialquilcarboxilico.
ES522883A0 (es)	1985-02-16	"procedimiento para la preparacion de un ester basico de acido 1, 4-dihidropiridin-3,5-dicarboxilico"
ES521430A0 (es)	1984-05-16	Un procedimiento para la preparacion de derivados del acido tetrahidrofurancarboxilico.
ES510931A0 (es)	1983-02-01	"un procedimiento para la preparacion del acido d-2-(6-metoxi-2-naftil)-propionico".
ES500032A0 (es)	1982-06-01	Un procedimiento para la preparacion de derivados del acido 7-oxo-1-azabiciclo (3,2,0) hept-2-en-2-carboxilico.
ES547345A0 (es)	1986-03-16	Procedimiento para la obtencion de acido 2,4-dicloro-5- fluor-benzoico
ES509913A0 (es)	1983-02-16	Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico.
ES545565A0 (es)	1987-03-01	Un procedimiento para la preparacion de derivados del acido fenil nonatetraenoico
ES545044A0 (es)	1986-09-01	Un nuevo procedimiento para la preparacion de derivados del acido cicloalquilidenmetilfenilacetico.
ES548913A0 (es)	1987-05-01	Un procedimiento para la produccion de 2h-imidazo-(1',2':1,2)-pirrolo-(3,4-b)-piridinas
ES538906A0 (es)	1986-01-01	Un procedimiento para la preparacion de nuevos derivados del acido tiazolilacetico.
ES512387A0 (es)	1983-02-01	"procedimiento para la preparacion del acido (2',4'-difluoro-4-bifenil)-oxipropionico".
ES539007A0 (es)	1986-03-16	Un procedimiento para la preparacion de acido fructosa 1,6 difosfato
ES508346A0 (es)	1982-11-16	Un procedimiento para la preparacion de derivados del acido 2 beta-clorometil-2 alfa-metilpenam-3 alfa-carboxilico.
ES525238A0 (es)	1985-08-16	Un procedimiento para la preparacion de derivados del acido penicilanico 6alfa-o-6beta-sustituidos.
ES548435A0 (es)	1986-12-01	Procedimiento para la obtencion de acido (5,r 6s)-2-aminome-til-6-(1r)-1-hidroxietil -2-penem-3-carboxilico cristalino
AR224028A1 (es)	1981-10-15	Un procedimiento para la produccion de acido 2,5-diceto-gluconico
ES522620A0 (es)	1984-09-01	Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico.
ES547054A0 (es)	1986-07-16	Un procedimiento para la preparacion de un compuesto de 1,3 -diacil-2-oxindol
ES515608A0 (es)	1983-11-01	Un procedimiento para la preparacion de derivados del acido pirido-1,2,3-1,4 benzoxazin-6-carboxilico.
ES534473A0 (es)	1985-06-01	Procedimiento para la obtencion del acido 2, 2-dimetil-5(2, 5-xililoxi) valerico