ME00962B - Benzimidazolski derivati - Google Patents
Benzimidazolski derivatiInfo
- Publication number
- ME00962B ME00962B MEP-2009-349A MEP34909A ME00962B ME 00962 B ME00962 B ME 00962B ME P34909 A MEP34909 A ME P34909A ME 00962 B ME00962 B ME 00962B
- Authority
- ME
- Montenegro
- Prior art keywords
- benzimidazole derivatives
- mammals
- compounds
- treatment
- cell growth
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Ovaj izum odnosi se na spoj Formule I (I) ili njegovu farmaceutsk i prihvatljivu so, gdje R1, R2, R3A, R3B, R4, R5, X, m i n su definirani u ovoj specifikaciji . Takvi novi benzimidazolski derivati korisni su u liječenju abnormalnog staničnog rasta, poput raka, kod sisavaca. Ovaj izum također se odnosi na postupak upotrebe takvih spojeva u liječenju abnormalnog staničnog rasta kod sisavaca, osobito ljudi , te na farmaceutske pripravke koji sadrže takve spojeve.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94728707P | 2007-06-29 | 2007-06-29 | |
| US4164508P | 2008-04-02 | 2008-04-02 | |
| PCT/IB2008/001575 WO2009004427A2 (en) | 2007-06-29 | 2008-06-16 | Benzimidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME00962B true ME00962B (me) | 2012-06-20 |
Family
ID=40161351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2009-349A ME00962B (me) | 2007-06-29 | 2008-06-16 | Benzimidazolski derivati |
Country Status (46)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101687841B (zh) | 2007-06-29 | 2013-07-10 | 辉瑞大药厂 | 苯并咪唑衍生物 |
| US9265734B2 (en) | 2008-09-03 | 2016-02-23 | Biomarin Pharmaceutical Inc. | Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors |
| RU2533825C2 (ru) * | 2009-06-11 | 2014-11-20 | Сиена Байотек С.П.А. | ПРОИЗВОДНЫЕ БЕНЗИМИДАЗОЛА И ИМИДАЗО[4,5-с]ПИРИДИНА, В КАЧЕСТВЕ АНТАГОНИСТА ПУТИ HEDGEHOG |
| WO2011024872A1 (ja) | 2009-08-26 | 2011-03-03 | 武田薬品工業株式会社 | 縮合複素環誘導体およびその用途 |
| US10010439B2 (en) | 2010-06-13 | 2018-07-03 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| US10420665B2 (en) | 2010-06-13 | 2019-09-24 | W. L. Gore & Associates, Inc. | Intragastric device for treating obesity |
| US8628554B2 (en) | 2010-06-13 | 2014-01-14 | Virender K. Sharma | Intragastric device for treating obesity |
| US9526648B2 (en) | 2010-06-13 | 2016-12-27 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| EP2630134B9 (en) | 2010-10-20 | 2018-04-18 | Pfizer Inc | Pyridine-2- derivatives as smoothened receptor modulators |
| JP5452459B2 (ja) | 2010-12-16 | 2014-03-26 | 株式会社Ｎｔｔドコモ | ホーム基地局及びハンドオーバ方法 |
| AU2012223509B2 (en) | 2011-02-28 | 2016-11-10 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US8957066B2 (en) | 2011-02-28 | 2015-02-17 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US10059723B2 (en) | 2011-02-28 | 2018-08-28 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| EP2684167B1 (en) * | 2011-03-08 | 2020-09-09 | Eutropics Pharmaceuticals, Inc. | Compositions and methods useful for treating diseases |
| FR2980477B1 (fr) | 2011-09-23 | 2013-10-18 | Centre Nat Rech Scient | Nouveaux composes modulateurs de la voie de signalisation des proteines hedgehog, leurs formes marquees, et applications |
| EP2844648B1 (en) * | 2011-09-26 | 2016-11-09 | Merck Patent GmbH | Benzyl piperidine compounds as lysophosphatidic acid (lpa) receptor antagonist |
| US20150150869A1 (en) | 2012-06-20 | 2015-06-04 | Eutropics Pharmaceuticals, Inc. | Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives |
| WO2014081953A1 (en) | 2012-11-21 | 2014-05-30 | Richard David J | Methods and compositions useful for treating diseases involving bcl-2 family proteins with isoquinoline and quinoline derivatives |
| JP6503338B2 (ja) | 2013-03-15 | 2019-04-17 | バイオマリン ファーマシューティカル インコーポレイテッド | Ｈｄａｃ阻害剤 |
| EP2996689A1 (en) | 2013-04-17 | 2016-03-23 | Albert-Ludwigs-Universität Freiburg | Compounds for use as bromodomain inhibitors |
| US10732182B2 (en) | 2013-08-01 | 2020-08-04 | Eutropics Pharmaceuticals, Inc. | Method for predicting cancer sensitivity |
| GB2519344A (en) * | 2013-10-18 | 2015-04-22 | Redx Pharma Ltd | Compounds |
| EP3063302B1 (en) | 2013-10-30 | 2019-12-04 | Eutropics Pharmaceuticals, Inc. | Methods for determining chemosensitivity and chemotoxicity |
| EP3666768B1 (en) * | 2015-04-24 | 2022-06-15 | Pfizer Inc. | Preparation process of a crystalline form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate; a crystalline form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea imidazole complex (1:1) |
| US10779980B2 (en) | 2016-04-27 | 2020-09-22 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| JP2020164722A (ja) * | 2019-03-29 | 2020-10-08 | デクセリアルズ株式会社 | 接着剤組成物 |
| US20230107634A1 (en) | 2020-01-28 | 2023-04-06 | Teva Pharmaceuticals International Gmbh | Processes for the preparation of glasdegib and salt thereof and solid state forms of glasdegib maleate and process for preparation thereof |
| CN113248475B (zh) * | 2020-02-11 | 2023-03-17 | 中国科学院上海药物研究所 | 一类杂环取代的苯并咪唑二聚体或其药学上可接受的盐、组合物及其用途 |
| EP4126237B1 (en) | 2020-03-26 | 2024-04-10 | LEK Pharmaceuticals d.d. | Dimaleate form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea |
| CN115997122A (zh) | 2020-06-26 | 2023-04-21 | 拉夸里亚创药株式会社 | 类维生素a与癌治疗剂的组合疗法有效的癌患者的选择方法、及类维生素a与癌治疗剂的组合药物 |
| WO2023002362A1 (en) | 2021-07-22 | 2023-01-26 | Pfizer Inc. | Treatment of hematological malignancy |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL366799A1 (en) | 2001-07-27 | 2005-02-07 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| ATE312090T1 (de) | 2001-12-04 | 2005-12-15 | Actelion Pharmaceuticals Ltd | 4-(piperidyl- und pyrrolidyl-alkyl-ureido)- chinoline als urotensin ii rezeptor antagonisten |
| TW200304820A (en) | 2002-03-25 | 2003-10-16 | Avanir Pharmaceuticals | Use of benzimidazole analogs in the treatment of cell proliferation |
| EP1551811A1 (en) | 2002-10-17 | 2005-07-13 | Amgen Inc. | Benzimidazole derivatives and their use as vanilloid receptor ligands |
| WO2005042495A1 (en) | 2003-10-21 | 2005-05-12 | Imclone Systems Incorporated | (benzimidazol-2-yl)-phenyl-phenyl-urea compounds and methods for inhibiting heparanase activity |
| CA2543918A1 (en) | 2003-10-28 | 2005-05-12 | Dean Wilson | Benzimidazoles useful as modulators of ion channels |
| NZ555419A (en) | 2004-11-03 | 2009-07-31 | Curis Inc | Mediators of the hedgehog gene signaling pathways, compositions and uses related thereto |
| DE102005012875B4 (de) | 2005-03-19 | 2006-11-16 | Sanofi-Aventis Deutschland Gmbh | Verwendung von Amino substituierten 8-N-Benzimidazolen |
| WO2006124780A2 (en) * | 2005-05-12 | 2006-11-23 | Kalypsys, Inc. | Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase |
| WO2008064830A1 (en) | 2006-11-27 | 2008-06-05 | Ucb Pharma, S.A. | Bicyclic and heterobicyclic derivatives, processes for preparing them and their pharmaceutical uses |
| EP2121626A1 (en) | 2006-12-15 | 2009-11-25 | Pfizer Products Inc. | Benzimidazole derivatives |
| CN101687841B (zh) * | 2007-06-29 | 2013-07-10 | 辉瑞大药厂 | 苯并咪唑衍生物 |
| US20120094974A1 (en) | 2008-06-17 | 2012-04-19 | Wei Chen | Smoothened receptor modulators |
| AU2009288399B2 (en) | 2008-08-25 | 2013-03-07 | Novartis Ag | Hedgehog pathway modulators |
-
2008
- 2008-06-16 CN CN200880022602XA patent/CN101687841B/zh active Active
- 2008-06-16 CA CA2690953A patent/CA2690953C/en active Active
- 2008-06-16 PL PL08762901T patent/PL2170860T3/pl unknown
- 2008-06-16 DK DK08762901.0T patent/DK2170860T5/en active
- 2008-06-16 JP JP2010514162A patent/JP4567099B2/ja active Active
- 2008-06-16 WO PCT/IB2008/001575 patent/WO2009004427A2/en active Application Filing
- 2008-06-16 ME MEP-2009-349A patent/ME00962B/me unknown
- 2008-06-16 AP AP2009005089A patent/AP2377A/xx active
- 2008-06-16 PT PT87629010T patent/PT2170860T/pt unknown
- 2008-06-16 NZ NZ581889A patent/NZ581889A/en unknown
- 2008-06-16 AU AU2008272641A patent/AU2008272641B2/en active Active
- 2008-06-16 EP EP08762901.0A patent/EP2170860B9/en active Active
- 2008-06-16 HU HUE08762901A patent/HUE030052T4/en unknown
- 2008-06-16 EA EA200971104A patent/EA016888B1/ru unknown
- 2008-06-16 GE GEAP200811622A patent/GEP20125702B/en unknown
- 2008-06-16 SI SI200831707A patent/SI2170860T1/sl unknown
- 2008-06-16 BR BRPI0813412A patent/BRPI0813412B8/pt active IP Right Grant
- 2008-06-16 ES ES08762901.0T patent/ES2609258T3/es active Active
- 2008-06-16 KR KR1020107001991A patent/KR101143246B1/ko active IP Right Grant
- 2008-06-16 LT LTEP08762901.0T patent/LT2170860T/lt unknown
- 2008-06-16 MY MYPI20095266A patent/MY148636A/en unknown
- 2008-06-16 RS RS20161132A patent/RS55395B9/sr unknown
- 2008-06-19 US US12/142,119 patent/US8148401B2/en active Active
- 2008-06-19 PA PA20088785401A patent/PA8785401A1/es unknown
- 2008-06-20 UY UY31164A patent/UY31164A1/es active IP Right Grant
- 2008-06-25 HN HN2008000974A patent/HN2008000974A/es unknown
- 2008-06-27 TW TW097124392A patent/TWI371451B/zh active
- 2008-06-27 PE PE2008001105A patent/PE20090772A1/es active IP Right Grant
- 2008-06-27 PE PE2012000473A patent/PE20121010A1/es active IP Right Grant
- 2008-06-27 CL CL2008001922A patent/CL2008001922A1/es unknown
- 2008-06-27 AR ARP080102792A patent/AR067346A1/es active IP Right Grant
-
2009
- 2009-11-30 IL IL202420A patent/IL202420A/en active IP Right Grant
- 2009-12-07 CR CR11150A patent/CR11150A/es unknown
- 2009-12-08 DO DO2009000278A patent/DOP2009000278A/es unknown
- 2009-12-14 EC EC2009009803A patent/ECSP099803A/es unknown
- 2009-12-18 NI NI200900219A patent/NI200900219A/es unknown
- 2009-12-21 GT GT200900328A patent/GT200900328A/es unknown
- 2009-12-21 CU CU2009000225A patent/CU23847B1/es active IP Right Grant
- 2009-12-23 CO CO09147462A patent/CO6160232A2/es unknown
- 2009-12-25 TN TNP2009000544A patent/TN2009000544A1/fr unknown
- 2009-12-29 MA MA32454A patent/MA31466B1/fr unknown
-
2010
- 2010-06-09 HK HK10105659.9A patent/HK1139658A1/xx unknown
- 2010-08-04 JP JP2010175465A patent/JP2010280693A/ja active Pending
-
2012
- 2012-02-24 US US13/404,169 patent/US8431597B2/en active Active
-
2016
- 2016-11-23 HR HRP20161562TT patent/HRP20161562T2/hr unknown
- 2016-12-14 CY CY20161101293T patent/CY1118650T1/el unknown
-
2020
- 2020-07-15 NL NL301057C patent/NL301057I2/nl unknown
- 2020-08-11 NO NO2020027C patent/NO2020027I1/no unknown
- 2020-08-12 CY CY2020028C patent/CY2020028I1/el unknown
- 2020-08-13 HU HUS2000031C patent/HUS2000031I1/hu unknown
- 2020-08-20 FR FR20C1038C patent/FR20C1038I2/fr active Active
- 2020-08-26 LT LTPA2020528C patent/LTC2170860I2/lt unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ME00962B (me) | Benzimidazolski derivati | |
| EA201170772A1 (ru) | Органические соединения | |
| NO20090295L (no) | Substituerte heteroarylderivater | |
| EA201100503A1 (ru) | Глюкозидные производные и их применения | |
| MX2009011090A (es) | Derivados de sulfonil amida para el tratamiento del crecimiento celular anormal. | |
| EA200970156A1 (ru) | Пиридизиноновые производные | |
| RS51661B (en) | NEW DIOSMETHINE DERIVATIVES, THE PROCEDURE FOR THEIR MAKING AND THE PHARMACEUTICAL MIXTURES CONTAINING THEM | |
| NI200800294A (es) | Nueva forma cristalina vi de la agomelatina, su procedimiento de preparacion y las composiciones farmacéuticas que la contienen. | |
| UA107175C2 (uk) | Спосіб і сполука, призначені для одержання інгібіторів контранспортера натрій-глюкози 2 типу, варіанти | |
| BRPI0915084B8 (pt) | composto, e, composição farmacêutica | |
| TW200732323A (en) | Organic compounds | |
| UY32156A (es) | Derivados sustituidos de la n2 - [1-(5 - fluoropirimidin -2-il) etil] - n4 - (1-metil - 1h-imidazol - 4 - il)) - pirimidina - 2,4 - diaminas y sus sales farmacéuticamente aceptables, proceso de preparación, composiciones conteniéndolos y aplicaciones. | |
| EA201001205A1 (ru) | Соединения, содержащие циклобутоксигруппу | |
| EA201101026A1 (ru) | Ингибиторы бета-секретазы | |
| EA200601271A1 (ru) | Новая кристаллическая форма iv агомелатина, способ её получения и фармацевтические композиции, которые её содержат | |
| EA201200471A1 (ru) | Простые эфирные производные бициклических гетероарилов | |
| ATE472529T1 (de) | Prolinamidderivate als natriumkanalmodulatoren | |
| JO2734B1 (en) | Organic compounds | |
| EA201001196A1 (ru) | Соединения 4-пиридинона и их применение для лечения рака | |
| NO20085317L (no) | Imidazoazepinonforbindelser | |
| EA201001855A1 (ru) | Соединения, содержащие циклобутоксигруппу | |
| CR9391A (es) | Derivados de indanil-piperazinas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
| EA201290229A1 (ru) | Производные спиролактама и их применение | |
| UY29894A1 (es) | Derivados del ácido (2-((2s)-2-hidroxipropil)oxi)fenil)acético y del ácido (2-((2s)-2-hidroxipropil)oxi)fenil) propanoico sustituidos, composiciones farmacéuticas conteniéndolo, procesos de preparación y aplicaciones | |
| RS53002B (en) | ANTI-CANCER UNIT AND PHARMACEUTICAL COPMOSITION CONTAINING IT |