MD960168A - Metodă şi compuşi pentru tratamentul infecţiilor virale - Google Patents
Metodă şi compuşi pentru tratamentul infecţiilor viraleInfo
- Publication number
- MD960168A MD960168A MD96-0168A MD960168A MD960168A MD 960168 A MD960168 A MD 960168A MD 960168 A MD960168 A MD 960168A MD 960168 A MD960168 A MD 960168A
- Authority
- MD
- Moldova
- Prior art keywords
- viral infections
- treatment
- compounds therefor
- compounds
- therefor
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title abstract 3
- 230000009385 viral infection Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Invenţia se referă la o metodă şi compuşi entru tratamentul infecţiilor virale la mamifere.În compuşi se foloseşte flavina şi derivaţi de flavină.Rezultatul tehnic constă în sporirea eficacităţii tratamentului infecţiilor virale.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939321558A GB9321558D0 (en) | 1993-10-19 | 1993-10-19 | Anti-viral agents |
| PCT/GB1994/002292 WO1995011028A1 (en) | 1993-10-19 | 1994-10-19 | Flavin derivatives as anti-viral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD960168A true MD960168A (ro) | 1998-04-30 |
Family
ID=10743784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD96-0168A MD960168A (ro) | 1993-10-19 | 1996-05-17 | Metodă şi compuşi pentru tratamentul infecţiilor virale |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0739208A1 (ro) |
| JP (1) | JPH09505804A (ro) |
| CN (1) | CN1140992A (ro) |
| AP (1) | AP620A (ro) |
| AU (1) | AU7943794A (ro) |
| BG (1) | BG100599A (ro) |
| BR (1) | BR9407862A (ro) |
| CA (2) | CA2123825A1 (ro) |
| CO (1) | CO4520283A1 (ro) |
| CZ (1) | CZ113796A3 (ro) |
| EE (1) | EE9600057A (ro) |
| GB (2) | GB9321558D0 (ro) |
| HR (1) | HRP940688A2 (ro) |
| HU (1) | HUT76322A (ro) |
| IL (1) | IL111338A0 (ro) |
| JO (1) | JO1866B1 (ro) |
| MA (1) | MA23356A1 (ro) |
| MD (1) | MD960168A (ro) |
| NO (1) | NO961547L (ro) |
| OA (1) | OA10579A (ro) |
| PE (1) | PE5596A1 (ro) |
| PL (1) | PL314008A1 (ro) |
| SK (1) | SK50696A3 (ro) |
| UY (1) | UY23844A1 (ro) |
| WO (1) | WO1995011028A1 (ro) |
| ZA (1) | ZA948191B (ro) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07188052A (ja) * | 1993-12-27 | 1995-07-25 | Sanwa Kagaku Kenkyusho Co Ltd | インターフェロン用作用効果増強剤及び該増強剤とインターフェロンとを含有する抗ウイルス活性増強組成物 |
| US5756479A (en) * | 1994-12-29 | 1998-05-26 | Research Development Foundation | Flavin adenine dinucleotide analogue inhibitors of monoamine oxidase |
| US7498156B2 (en) | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
| US7049110B2 (en) | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
| US7220747B2 (en) | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
| US7094378B1 (en) | 2000-06-15 | 2006-08-22 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
| US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
| AU2003299486A1 (en) * | 2002-05-10 | 2004-06-03 | The Ohio State University | Flavin n-oxides: new anti-cancer agents and pathogen eradication agents |
| ITTO20020622A1 (it) | 2002-07-16 | 2004-01-16 | Dayco Europe Srl | Gruppo integrato puleggia-smorzatore torsionale |
| CN100413866C (zh) * | 2002-08-02 | 2008-08-27 | 中国人民解放军军事医学科学院放射医学研究所 | 核黄素衍生物及其制备方法与应用 |
| EP2545788A1 (de) * | 2011-07-13 | 2013-01-16 | Martin Hulliger | Diätisches Mehrkomponentensystem |
| JP2018131410A (ja) * | 2017-02-15 | 2018-08-23 | ヒノキ新薬株式会社 | カスパーゼ−3阻害剤とその用途 |
| EP3700512A4 (en) * | 2017-10-24 | 2021-08-11 | Lunella Biotech, Inc. | MITOFLAVOSCINE: TARGETING FLAVINAL ENZYMES ELIMINATES CANCER STEM CELLS (CSCS) BY INHIBITING MITOCHONDRIAL BREATHING |
| BR112022000175A2 (pt) * | 2019-07-09 | 2022-02-22 | Dsm Ip Assets Bv | Reduzindo a atividade viral de elafibranor com riboflavina ou dha |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4219545A (en) * | 1979-03-23 | 1980-08-26 | Collins Calvin E | Treatment of infectious keratoconjunctivitis in animals |
| US4264601A (en) * | 1979-06-12 | 1981-04-28 | The Board Of Regents Of The University Of Oklahoma | Antihypertensive agents and their use in treatment of hypertension |
| US4500524A (en) * | 1982-09-15 | 1985-02-19 | Trustees Of Boston University | Tranquilizing and reducing or preventing seizures |
| WO1991002529A2 (en) * | 1989-08-14 | 1991-03-07 | John Bennett Kizer | Product and method for killing abnormal vertebrate cells |
| JP2727471B2 (ja) * | 1989-09-14 | 1998-03-11 | 三井農林株式会社 | インフルエンザウィルス感染予防剤 |
| US5192264A (en) * | 1989-10-06 | 1993-03-09 | The Beth Israel Hospital Association | Methods and apparatus for treating disease states using oxidized lipoproteins |
| US5217716A (en) * | 1990-07-18 | 1993-06-08 | The Beth Israel Hospital Association | Method for treating viral infections using oxidized lipoproteins |
| FR2674753B1 (fr) * | 1991-04-02 | 1995-03-10 | Jean Berque | Nouvelles indications therapeutiques, en particulier pour le traitement du sida, d'un medicament deja existant et fabrique a partir d'une molecule denuee de contre-indications et d'effets indesirables. |
| NZ244270A (en) * | 1991-09-13 | 1995-07-26 | Eisai Co Ltd | Injectable composition comprising riboflavin |
| WO1993010784A1 (en) * | 1991-11-25 | 1993-06-10 | University Of Michigan | Therapeutic composition and method for preventing reperfusion injury |
| JP3073309B2 (ja) * | 1992-03-27 | 2000-08-07 | 雪印乳業株式会社 | シアル酸結合5−デアザフラビン系化合物 |
-
1993
- 1993-10-19 GB GB939321558A patent/GB9321558D0/en active Pending
-
1994
- 1994-01-19 JO JO19941866A patent/JO1866B1/en active
- 1994-05-18 CA CA2123825A patent/CA2123825A1/en active Pending
- 1994-10-18 MA MA23679A patent/MA23356A1/fr unknown
- 1994-10-19 ZA ZA948191A patent/ZA948191B/xx unknown
- 1994-10-19 CO CO94047671A patent/CO4520283A1/es unknown
- 1994-10-19 GB GB9421099A patent/GB2283913A/en not_active Withdrawn
- 1994-10-19 CA CA002174552A patent/CA2174552A1/en not_active Abandoned
- 1994-10-19 AP APAP/P/1994/000695A patent/AP620A/en active
- 1994-10-19 HU HU9601006A patent/HUT76322A/hu unknown
- 1994-10-19 AU AU79437/94A patent/AU7943794A/en not_active Abandoned
- 1994-10-19 PL PL94314008A patent/PL314008A1/xx unknown
- 1994-10-19 BR BR9407862A patent/BR9407862A/pt not_active Application Discontinuation
- 1994-10-19 CZ CZ961137A patent/CZ113796A3/cs unknown
- 1994-10-19 CN CN94194350A patent/CN1140992A/zh active Pending
- 1994-10-19 IL IL11133894A patent/IL111338A0/xx unknown
- 1994-10-19 HR HR9321558.0A patent/HRP940688A2/hr not_active Application Discontinuation
- 1994-10-19 EE EE9600057A patent/EE9600057A/xx unknown
- 1994-10-19 WO PCT/GB1994/002292 patent/WO1995011028A1/en not_active Ceased
- 1994-10-19 PE PE1994253128A patent/PE5596A1/es not_active Application Discontinuation
- 1994-10-19 JP JP7511518A patent/JPH09505804A/ja active Pending
- 1994-10-19 UY UY23844A patent/UY23844A1/es unknown
- 1994-10-19 SK SK506-96A patent/SK50696A3/sk unknown
- 1994-10-19 EP EP94930272A patent/EP0739208A1/en not_active Withdrawn
-
1996
- 1996-04-18 NO NO961547A patent/NO961547L/no unknown
- 1996-04-18 OA OA60815A patent/OA10579A/en unknown
- 1996-05-17 BG BG100599A patent/BG100599A/xx unknown
- 1996-05-17 MD MD96-0168A patent/MD960168A/ro not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL111338A0 (en) | 1994-12-29 |
| EP0739208A1 (en) | 1996-10-30 |
| JO1866B1 (en) | 1995-12-27 |
| AU7943794A (en) | 1995-05-08 |
| HU9601006D0 (en) | 1996-06-28 |
| AP9400695A0 (en) | 1995-01-31 |
| CN1140992A (zh) | 1997-01-22 |
| CZ113796A3 (en) | 1996-11-13 |
| GB2283913A (en) | 1995-05-24 |
| AP620A (en) | 1997-10-14 |
| HRP940688A2 (en) | 1997-04-30 |
| CA2123825A1 (en) | 1995-04-20 |
| CO4520283A1 (es) | 1997-10-15 |
| SK50696A3 (en) | 1997-01-08 |
| GB9321558D0 (en) | 1993-12-08 |
| PL314008A1 (en) | 1996-08-05 |
| GB9421099D0 (en) | 1994-12-07 |
| BG100599A (en) | 1997-02-28 |
| NO961547L (no) | 1996-06-19 |
| OA10579A (en) | 2002-06-19 |
| ZA948191B (en) | 1995-06-08 |
| PE5596A1 (es) | 1996-04-18 |
| MA23356A1 (fr) | 1995-07-01 |
| UY23844A1 (es) | 1995-03-28 |
| CA2174552A1 (en) | 1995-04-27 |
| BR9407862A (pt) | 1997-05-20 |
| HUT76322A (en) | 1997-08-28 |
| NO961547D0 (no) | 1996-04-18 |
| EE9600057A (et) | 1996-10-15 |
| WO1995011028A1 (en) | 1995-04-27 |
| JPH09505804A (ja) | 1997-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA1A | Withdrawn application |
Free format text: 19990225 |