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MC2039A1 - Proteine ayant un ou plusieurs determinants immuno-reactifs et/ou antigeniques d'un antigene de surface d'eimeria,utilisation et procede de preparation - Google Patents

Proteine ayant un ou plusieurs determinants immuno-reactifs et/ou antigeniques d'un antigene de surface d'eimeria,utilisation et procede de preparation

Info

Publication number
MC2039A1
MC2039A1 MC892053A MC2053A MC2039A1 MC 2039 A1 MC2039 A1 MC 2039A1 MC 892053 A MC892053 A MC 892053A MC 2053 A MC2053 A MC 2053A MC 2039 A1 MC2039 A1 MC 2039A1
Authority
MC
Monaco
Prior art keywords
immuno
reactive
protein
preparation
surface antigen
Prior art date
Application number
MC892053A
Other languages
English (en)
French (fr)
Inventor
Altenburger Werner
Binger Mary-Helen
Anthony Chizzonite Richard
Allen Kramer Richard
Thomas Lomedico Peter
J Mcandrew Stephen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2039A1 publication Critical patent/MC2039A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455Eimeria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MC892053A 1988-06-03 1989-06-02 Proteine ayant un ou plusieurs determinants immuno-reactifs et/ou antigeniques d'un antigene de surface d'eimeria,utilisation et procede de preparation MC2039A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20272188A 1988-06-03 1988-06-03

Publications (1)

Publication Number Publication Date
MC2039A1 true MC2039A1 (fr) 1990-05-30

Family

ID=22750986

Family Applications (1)

Application Number Title Priority Date Filing Date
MC892053A MC2039A1 (fr) 1988-06-03 1989-06-02 Proteine ayant un ou plusieurs determinants immuno-reactifs et/ou antigeniques d'un antigene de surface d'eimeria,utilisation et procede de preparation

Country Status (22)

Country Link
US (2) US5661015A (xx)
EP (1) EP0344808B1 (xx)
JP (1) JP3051130B2 (xx)
KR (1) KR0156545B1 (xx)
CN (3) CN1040126C (xx)
AR (1) AR241942A1 (xx)
AT (1) ATE120489T1 (xx)
AU (1) AU635704B2 (xx)
CA (1) CA1340538C (xx)
DE (1) DE68921923T2 (xx)
DK (1) DK272889A (xx)
ES (1) ES2070866T3 (xx)
FI (1) FI101453B (xx)
HU (1) HU212505B (xx)
IE (1) IE67544B1 (xx)
IL (1) IL90489A0 (xx)
MC (1) MC2039A1 (xx)
NO (1) NO303876B1 (xx)
NZ (1) NZ229377A (xx)
PT (1) PT90727B (xx)
YU (1) YU47880B (xx)
ZA (1) ZA893740B (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5174993A (en) * 1981-12-24 1992-12-29 Health Research Inc. Recombinant avipox virus and immunological use thereof
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
EP0432168B1 (en) * 1988-07-05 1996-10-16 British Technology Group Usa Inc Genetically engineered coccidiosis vaccine
ZA902147B (en) * 1989-03-28 1990-12-28 Akzo Nv Coccidiosis vaccine
DE68909041T2 (de) * 1989-06-21 1994-01-13 Akzo Nv Eimeria tenella-Vakzin.
ZA9010461B (en) * 1990-01-26 1991-10-30 Hoffmann La Roche Recombinant coccidiosis vaccines-5-7 eimeria surface antigen
CA2106093A1 (en) * 1991-03-14 1992-09-15 David E. Harwood Recombinant anticoccidial vaccine
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
DE69520509T2 (de) 1995-06-07 2001-07-12 Pfizer Inc., New York In ovo impfung gegen coccidiose
ES2158108T3 (es) 1995-06-07 2001-09-01 Pfizer Vacunacion in ovo contra la coccidiosis.
DE69635472T2 (de) * 1995-07-03 2006-04-13 Akzo Nobel N.V. Impfstoff gegen Geflügelkokzidose
EP0921814A4 (en) * 1996-03-29 2001-10-04 Life Technologies Inc Process for increasing the viability and transformation efficiency of bacteria during storage at low temperatures
US6632923B1 (en) 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US6627205B2 (en) 1997-12-01 2003-09-30 Pfizer Incorporated Ovo vaccination against coccidiosis
US6984378B1 (en) 1999-02-26 2006-01-10 Pfizer, Inc. Method for the purification, recovery, and sporulation of cysts and oocysts
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
KR100490669B1 (ko) * 2001-08-30 2005-05-19 (주)아비코아생명공학연구소 조류 콕시듐증을 유발하는 에이메리아 종의 포자소체 표면항원에 대한 scFv 재조합 항체
DE60237977D1 (de) 2001-08-30 2010-11-25 Embrex Inc Verbesserte verfahren zur herstellung von oozysten
JP3995541B2 (ja) * 2002-06-28 2007-10-24 株式会社ゲン・コーポレーション 抗鶏コクシジウム症組成物
DE10330235A1 (de) * 2003-07-04 2005-01-20 Bayer Healthcare Ag Neues Eimeria Gen und Protein sowie deren Verwendung
CA2579635A1 (en) * 2003-09-10 2005-03-17 Baxter International Inc. Peptides that inhibit complement activation
EP1742656B1 (en) * 2004-03-12 2010-06-16 University Of Georgia Research Foundation, Inc. Novel peanut skin extract as a vaccine adjuvant
US7087425B2 (en) * 2004-03-31 2006-08-08 Embrex, Inc. Method of purifying oocysts using enzymatic digestion of fecal debris
US20110078828A1 (en) * 2004-09-10 2011-03-31 Guardian Biotechnologies Inc. Multi epitope vaccine for poultry
EP1666489B1 (en) * 2004-12-01 2007-11-21 Zeon Corporation DNA encoding an antigenic protein of eimeria apical membrane antigen 1 and use thereof
CN100398156C (zh) * 2005-11-23 2008-07-02 南京农业大学 用于预防鸡球虫病的免疫调节型dna疫苗
US20080194006A1 (en) * 2007-02-08 2008-08-14 Embrex, Inc. Methods of releasing sporocysts from oocysts using controlled shear forces
US11701683B2 (en) 2010-12-22 2023-07-18 The Procter & Gamble Company Methods for foil stamping parts having asymmetrical edges
WO2018115229A1 (en) 2016-12-22 2018-06-28 Intervet International B.V. Eimeria vaccine with improved efficacy
AU2020283954A1 (en) * 2019-05-28 2021-12-16 Case Western Reserve University Compositions and methods for preserving DNA methylation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
DE2814039C3 (de) 1978-03-31 1981-02-19 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Herstellung von Hybrid-Bakterien
EP0135073A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
US4650676A (en) 1983-08-19 1987-03-17 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozoites of Eimeria spp.
EP0135712A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
US4710377A (en) * 1983-08-19 1987-12-01 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of Eimeria spp.
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4874705A (en) * 1985-05-16 1989-10-17 Solvay & Cie, S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US5187080A (en) * 1984-06-05 1993-02-16 Solvay & Cie S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US4639372A (en) 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
EP0190254A4 (en) * 1984-07-05 1987-03-09 Genex Corp GENE CLONE AND PROCESS FOR THE PREPARATION AND USE THEREOF.
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
DE3650540T2 (de) * 1985-12-03 1997-02-27 Solvay Antigene Proteine und diese enthaltende Impfstoffe zur Verhütung von Kokzidiose
EP0241139A3 (en) * 1986-03-13 1989-04-19 Merck & Co. Inc. Anti-idiotypic vaccine for coccidiosis
US5496550A (en) * 1986-08-14 1996-03-05 Chilwalner Method of reducing the output of Eimeria oocysts from a newborn chick
ATE145245T1 (de) * 1987-03-06 1996-11-15 Amgen Boulder Inc Polypeptide zur verwendung bei der diagnose von kokkidien-infektion und rekombinant-dns, verfahren zur herstellung derselben
EP0315073A2 (en) * 1987-11-02 1989-05-10 Matsushita Electric Industrial Co., Ltd. A composition for pattern forming materials
NZ227595A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Recombinant production of eimeria tenella antigens and their use
NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
AU620366B2 (en) * 1988-02-12 1992-02-20 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated response and method of producing the same
DE3926461A1 (de) * 1989-07-15 1991-01-24 Suttner Gmbh & Co Kg Ventilpistole, insbesondere fuer ein hochdruckreinigungsgeraet

Also Published As

Publication number Publication date
FI101453B1 (fi) 1998-06-30
CN1186695A (zh) 1998-07-08
DE68921923T2 (de) 1995-08-10
CN1038837A (zh) 1990-01-17
CN1040126C (zh) 1998-10-07
HU212505B (en) 1996-07-29
FI892714A (fi) 1989-12-04
EP0344808B1 (en) 1995-03-29
CN1076204C (zh) 2001-12-19
AU3601689A (en) 1989-12-07
DK272889A (da) 1989-12-04
YU113889A (en) 1991-10-31
IE891812L (en) 1989-12-03
IL90489A0 (en) 1990-01-18
KR910000183A (ko) 1991-01-29
IE67544B1 (en) 1996-04-17
NZ229377A (en) 1992-06-25
AR241942A1 (es) 1993-01-29
CN1187368A (zh) 1998-07-15
ZA893740B (en) 1990-02-28
US5661015A (en) 1997-08-26
CA1340538C (en) 1999-05-11
PT90727A (pt) 1989-12-29
JP3051130B2 (ja) 2000-06-12
AU635704B2 (en) 1993-04-01
HUT52963A (en) 1990-09-28
JPH037594A (ja) 1991-01-14
PT90727B (pt) 1994-11-30
CN1077438C (zh) 2002-01-09
FI101453B (fi) 1998-06-30
EP0344808A1 (en) 1989-12-06
YU47880B (sh) 1996-05-20
NO892251L (no) 1989-12-04
ATE120489T1 (de) 1995-04-15
KR0156545B1 (ko) 1998-11-16
NO892251D0 (no) 1989-06-02
DK272889D0 (da) 1989-06-02
US20030175311A1 (en) 2003-09-18
DE68921923D1 (de) 1995-05-04
FI892714A0 (fi) 1989-06-02
NO303876B1 (no) 1998-09-14
ES2070866T3 (es) 1995-06-16

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