MA56551A - Procédés et intermédiaires pour la production de composés de diazaspiro-lactame - Google Patents
Procédés et intermédiaires pour la production de composés de diazaspiro-lactameInfo
- Publication number
- MA56551A MA56551A MA056551A MA56551A MA56551A MA 56551 A MA56551 A MA 56551A MA 056551 A MA056551 A MA 056551A MA 56551 A MA56551 A MA 56551A MA 56551 A MA56551 A MA 56551A
- Authority
- MA
- Morocco
- Prior art keywords
- diazaspirolactam
- intermediates
- compounds
- production
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962865840P | 2019-06-24 | 2019-06-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA56551A true MA56551A (fr) | 2022-04-27 |
Family
ID=74060351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA056551A MA56551A (fr) | 2019-06-24 | 2020-06-23 | Procédés et intermédiaires pour la production de composés de diazaspiro-lactame |
Country Status (7)
Country | Link |
---|---|
US (1) | US12215114B2 (fr) |
EP (2) | EP3986400B1 (fr) |
CN (1) | CN114269338B (fr) |
ES (1) | ES2991258T3 (fr) |
MA (1) | MA56551A (fr) |
TW (1) | TW202110852A (fr) |
WO (1) | WO2020263848A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020263848A1 (fr) | 2019-06-24 | 2020-12-30 | Naurex Inc. | Procédés et intermédiaires pour la production de composés de diazaspiro-lactame |
JP7617043B2 (ja) | 2019-06-24 | 2025-01-17 | ノーレックス インコーポレイテッド | tert-ブチル(S)-2-((2S,3R)-1-アミノ-3-ヒドロキシ-1-オキソブタン-2-イル)-1-オキソ-2,5-ジアザスピロ[3.4]オクタン-5-カルボキシレートの固体形態およびそれらを調製する方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688787A (en) | 1991-07-23 | 1997-11-18 | Schering Corporation | Substituted β-lactam compounds useful as hypochlesterolemic agents and processes for the preparation thereof |
CA2740628C (fr) * | 2008-09-18 | 2018-05-01 | Naurex, Inc. | Modulateurs de recepteur nmda et leurs utilisations |
SG11201505937SA (en) * | 2013-01-29 | 2015-09-29 | Naurex Inc | Spiro-lactam nmda receptor modulators and uses thereof |
LT3514158T (lt) | 2013-01-29 | 2023-02-10 | Aptinyx Inc. | Spirolaktaminiai nmda receptoriaus moduliatoriai ir jų panaudojimas |
BR112015018092A2 (pt) * | 2013-01-29 | 2017-07-18 | Naurex Inc | moduladores de receptor de nmda de espiro-lactama e usos dos mesmos |
US20140238699A1 (en) | 2013-02-22 | 2014-08-28 | Vetco Gray Inc. | Wellhead annulus seal having a wickered surface |
CA3024606C (fr) * | 2016-05-19 | 2019-09-03 | Aptinyx Inc. | Modulateurs de recepteurs nmda de spiro-lactame et utilisations associees |
WO2017201285A1 (fr) * | 2016-05-19 | 2017-11-23 | Aptinyx Inc. | Modulateurs spirolactames des récepteurs nmda et leurs utilisations |
WO2019152696A1 (fr) | 2018-01-31 | 2019-08-08 | Aptinyx Inc. | Spiro-lactame modulateur de récepteurs nmda et leurs utilisations |
WO2020263848A1 (fr) | 2019-06-24 | 2020-12-30 | Naurex Inc. | Procédés et intermédiaires pour la production de composés de diazaspiro-lactame |
JP7617043B2 (ja) * | 2019-06-24 | 2025-01-17 | ノーレックス インコーポレイテッド | tert-ブチル(S)-2-((2S,3R)-1-アミノ-3-ヒドロキシ-1-オキソブタン-2-イル)-1-オキソ-2,5-ジアザスピロ[3.4]オクタン-5-カルボキシレートの固体形態およびそれらを調製する方法 |
-
2020
- 2020-06-23 WO PCT/US2020/039164 patent/WO2020263848A1/fr unknown
- 2020-06-23 EP EP20832011.9A patent/EP3986400B1/fr active Active
- 2020-06-23 MA MA056551A patent/MA56551A/fr unknown
- 2020-06-23 CN CN202080059426.8A patent/CN114269338B/zh active Active
- 2020-06-23 EP EP24195355.3A patent/EP4484431A3/fr active Pending
- 2020-06-23 ES ES20832011T patent/ES2991258T3/es active Active
- 2020-06-23 US US17/621,905 patent/US12215114B2/en active Active
- 2020-06-23 TW TW109121351A patent/TW202110852A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3986400A1 (fr) | 2022-04-27 |
EP3986400B1 (fr) | 2024-08-21 |
EP3986400C0 (fr) | 2024-08-21 |
US20220259217A1 (en) | 2022-08-18 |
EP3986400A4 (fr) | 2023-05-17 |
US12215114B2 (en) | 2025-02-04 |
EP4484431A3 (fr) | 2025-03-26 |
WO2020263848A1 (fr) | 2020-12-30 |
CN114269338B (zh) | 2025-02-18 |
ES2991258T3 (es) | 2024-12-03 |
TW202110852A (zh) | 2021-03-16 |
CN114269338A (zh) | 2022-04-01 |
EP4484431A2 (fr) | 2025-01-01 |
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