MA55761A - Formulations et anticorps anti-cd38 - Google Patents
Formulations et anticorps anti-cd38Info
- Publication number
- MA55761A MA55761A MA055761A MA55761A MA55761A MA 55761 A MA55761 A MA 55761A MA 055761 A MA055761 A MA 055761A MA 55761 A MA55761 A MA 55761A MA 55761 A MA55761 A MA 55761A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- formulations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962837518P | 2019-04-23 | 2019-04-23 | |
| US201962859699P | 2019-06-10 | 2019-06-10 | |
| EP20305145 | 2020-02-17 | ||
| EP20305146 | 2020-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA55761A true MA55761A (fr) | 2022-03-02 |
Family
ID=70739160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA055761A MA55761A (fr) | 2019-04-23 | 2020-04-23 | Formulations et anticorps anti-cd38 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP3958898A1 (fr) |
| JP (1) | JP7602485B2 (fr) |
| KR (1) | KR20220003562A (fr) |
| CN (2) | CN120757645A (fr) |
| AU (1) | AU2020261039A1 (fr) |
| BR (1) | BR112021021060A2 (fr) |
| CA (1) | CA3137365A1 (fr) |
| CO (1) | CO2021015462A2 (fr) |
| IL (1) | IL287477A (fr) |
| MA (1) | MA55761A (fr) |
| MX (1) | MX2021012967A (fr) |
| MY (1) | MY206426A (fr) |
| SG (1) | SG11202111602YA (fr) |
| TW (1) | TWI878289B (fr) |
| WO (1) | WO2020219681A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240123827A (ko) * | 2021-12-16 | 2024-08-14 | 상하이 바오 파마슈티컬스 컴퍼니 리미티드 | 항면역글로불린 분해 효소에 의해 효소 절단된 Fc 변이체 |
| WO2024023843A1 (fr) * | 2022-07-26 | 2024-02-01 | Dr. Reddy’S Laboratories Limited | Formulation pharmaceutique d'un anticorps thérapeutique et ses préparations |
| WO2025245526A1 (fr) * | 2024-05-24 | 2025-11-27 | Research Institute At Nationwide Children's Hospital | Compositions de liaison à la protéine cd -38 et procédés s'y rapportant |
| CN120535629B (zh) * | 2025-04-22 | 2026-01-23 | 西安市中心血站(陕西省血液中心) | 一种用于抑制cd38单抗对输血相容性检测干扰的抗体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2925912T3 (es) | 2004-07-10 | 2022-10-20 | The Institute For Cancer Res | Líneas de células asesinas naturales humanas genéticamente modificadas |
| DK2471813T3 (en) * | 2004-07-15 | 2015-03-02 | Xencor Inc | Optimized Fc variants |
| EP1914242A1 (fr) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Nouveau anticorps Anti-CD38 pour le traitement du cancer |
| EP3559049B1 (fr) * | 2011-10-28 | 2025-06-11 | Teva Pharmaceuticals Australia Pty Ltd | Produits de recombinaison de polypeptide et utilisations de ceux-ci |
| US10617757B2 (en) * | 2014-08-08 | 2020-04-14 | The Regents Of The University Of California | Methods for treating multiple myeloma |
| BR112018008901A8 (pt) * | 2015-11-03 | 2019-02-26 | Janssen Biotech Inc | formulações subcutâneas de anticorpos anti-cd 38 e seus usos |
| CA3028238C (fr) * | 2016-06-30 | 2024-01-02 | Celltrion Inc. | Preparation pharmaceutique liquide stable |
| UA129862C2 (uk) * | 2017-05-02 | 2025-08-27 | Мерк Шарп Енд Доум Елелсі | Склад для лікування злоякісної пухлини або хронічної інфекції |
| US20190099489A1 (en) * | 2017-09-29 | 2019-04-04 | Janssen Biotech, Inc. | Novel Formulations Which Stabilize Low Dose Antibody Compositions |
| CN108752475B (zh) * | 2018-06-14 | 2021-07-30 | 北京智仁美博生物科技有限公司 | 抗人cd38抗体及其用途 |
-
2020
- 2020-04-23 MA MA055761A patent/MA55761A/fr unknown
- 2020-04-23 TW TW109113639A patent/TWI878289B/zh active
- 2020-04-23 MX MX2021012967A patent/MX2021012967A/es unknown
- 2020-04-23 CN CN202510964194.5A patent/CN120757645A/zh active Pending
- 2020-04-23 CA CA3137365A patent/CA3137365A1/fr active Pending
- 2020-04-23 EP EP20726267.6A patent/EP3958898A1/fr active Pending
- 2020-04-23 SG SG11202111602YA patent/SG11202111602YA/en unknown
- 2020-04-23 JP JP2021562989A patent/JP7602485B2/ja active Active
- 2020-04-23 BR BR112021021060A patent/BR112021021060A2/pt unknown
- 2020-04-23 WO PCT/US2020/029531 patent/WO2020219681A1/fr not_active Ceased
- 2020-04-23 KR KR1020217037641A patent/KR20220003562A/ko not_active Ceased
- 2020-04-23 AU AU2020261039A patent/AU2020261039A1/en active Pending
- 2020-04-23 CN CN202080030148.3A patent/CN114269375A/zh active Pending
- 2020-04-23 MY MYPI2021006312A patent/MY206426A/en unknown
-
2021
- 2021-10-21 IL IL287477A patent/IL287477A/en unknown
- 2021-11-17 CO CONC2021/0015462A patent/CO2021015462A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220003562A (ko) | 2022-01-10 |
| WO2020219681A1 (fr) | 2020-10-29 |
| CA3137365A1 (fr) | 2020-10-29 |
| BR112021021060A2 (pt) | 2021-12-14 |
| EP3958898A1 (fr) | 2022-03-02 |
| CN120757645A (zh) | 2025-10-10 |
| CO2021015462A2 (es) | 2021-12-10 |
| AU2020261039A1 (en) | 2021-12-09 |
| CN114269375A (zh) | 2022-04-01 |
| MX2021012967A (es) | 2022-01-18 |
| SG11202111602YA (en) | 2021-11-29 |
| TW202104269A (zh) | 2021-02-01 |
| TWI878289B (zh) | 2025-04-01 |
| JP2022529502A (ja) | 2022-06-22 |
| MY206426A (en) | 2024-12-17 |
| JP7602485B2 (ja) | 2024-12-18 |
| IL287477A (en) | 2021-12-01 |
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