[go: up one dir, main page]

MA49754B1 - Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag - Google Patents

Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag

Info

Publication number
MA49754B1
MA49754B1 MA49754A MA49754A MA49754B1 MA 49754 B1 MA49754 B1 MA 49754B1 MA 49754 A MA49754 A MA 49754A MA 49754 A MA49754 A MA 49754A MA 49754 B1 MA49754 B1 MA 49754B1
Authority
MA
Morocco
Prior art keywords
day
velusetrag
methods
treating gastroparesis
symptoms
Prior art date
Application number
MA49754A
Other languages
English (en)
Other versions
MA49754A (fr
Inventor
Christopher Noel Barnes
Giuseppe Claudio Viscomi
Cecilia RENZULLI
Maria Grimaldi
Original Assignee
Alfasigma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfasigma S.P.A. filed Critical Alfasigma S.P.A.
Publication of MA49754A publication Critical patent/MA49754A/fr
Publication of MA49754B1 publication Critical patent/MA49754B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des méthodes et des compositions pharmaceutiques pour le traitement de tous les symptômes de la gastroparésie chez un patient humain, la méthode comprenant l'administration au patient humain d'environ 0,5 mg/jour à environ 30 mg/jour, environ 0,5 mg/jour à environ 15 mg/jour, environ 0,5 mg/jour à environ 5 mg/jour, ou environ 5 mg/jour, de velusetrag ou d'un sel pharmaceutiquement acceptable de celui-ci.
MA49754A 2017-07-31 2018-07-30 Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag MA49754B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762539229P 2017-07-31 2017-07-31
EP18756041.2A EP3661518B1 (fr) 2017-07-31 2018-07-30 Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag
PCT/US2018/044337 WO2019027881A1 (fr) 2017-07-31 2018-07-30 Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag

Publications (2)

Publication Number Publication Date
MA49754A MA49754A (fr) 2020-06-10
MA49754B1 true MA49754B1 (fr) 2024-10-31

Family

ID=63245036

Family Applications (1)

Application Number Title Priority Date Filing Date
MA49754A MA49754B1 (fr) 2017-07-31 2018-07-30 Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag

Country Status (30)

Country Link
US (1) US11642339B2 (fr)
EP (1) EP3661518B1 (fr)
JP (2) JP7431721B2 (fr)
KR (1) KR102692887B1 (fr)
CN (1) CN110996961A (fr)
AU (1) AU2018309667B2 (fr)
BR (1) BR112020000482A2 (fr)
CA (1) CA3069989A1 (fr)
CL (1) CL2019003598A1 (fr)
DK (1) DK3661518T3 (fr)
EA (1) EA202090416A1 (fr)
ES (1) ES2991549T3 (fr)
FI (1) FI3661518T3 (fr)
HR (1) HRP20241359T1 (fr)
HU (1) HUE068595T2 (fr)
IL (1) IL272023B2 (fr)
LT (1) LT3661518T (fr)
MA (1) MA49754B1 (fr)
MD (1) MD3661518T2 (fr)
MX (1) MX2020001217A (fr)
PL (1) PL3661518T3 (fr)
PT (1) PT3661518T (fr)
RS (1) RS66049B1 (fr)
SG (1) SG11201912266QA (fr)
SI (1) SI3661518T1 (fr)
SM (1) SMT202400447T1 (fr)
TW (1) TW201909896A (fr)
UA (1) UA125596C2 (fr)
WO (1) WO2019027881A1 (fr)
ZA (1) ZA201908495B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023346889A1 (en) 2022-09-20 2025-02-20 Alfasigma S.P.A. Velusetrag for use in the treatment of chronic intestinal pseudo-obstruction (cipo)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI377206B (en) * 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
MX2008010555A (es) 2006-02-16 2008-09-15 Theravance Inc Proceso para preparar intermediarios de compuestos agonistas de receptor de 5-ht4.
HUE038141T2 (hu) 2009-04-13 2018-10-29 Theravance Biopharma R&D Ip Llc 5-HT4 receptor agonisták és acetilkolinészteráz inhibitorok kombinációi kognitív rendellenességek kezelésére
EP2744493A1 (fr) * 2011-08-18 2014-06-25 Shire AG Combinaisons d'un agoniste de récepteur 5-ht4 et d'un inhibiteur de pde4 pour utilisation en thérapie
PL2747561T3 (pl) * 2011-08-25 2018-11-30 Evoke Pharma, Inc. Leczenie objawów związanych z gastroparezą u osobników płci żeńskiej

Also Published As

Publication number Publication date
DK3661518T3 (da) 2024-10-07
JP2020529415A (ja) 2020-10-08
PL3661518T3 (pl) 2024-11-18
FI3661518T3 (fi) 2024-10-10
PT3661518T (pt) 2024-11-04
LT3661518T (lt) 2024-10-25
EP3661518A1 (fr) 2020-06-10
IL272023A (en) 2020-03-31
KR102692887B1 (ko) 2024-08-08
AU2018309667A1 (en) 2020-02-06
EA202090416A1 (ru) 2020-05-25
JP7431721B2 (ja) 2024-02-15
RS66049B1 (sr) 2024-11-29
HRP20241359T1 (hr) 2025-01-31
CN110996961A (zh) 2020-04-10
SI3661518T1 (sl) 2025-01-31
US20190030022A1 (en) 2019-01-31
WO2019027881A1 (fr) 2019-02-07
EP3661518B1 (fr) 2024-08-28
SG11201912266QA (en) 2020-01-30
SMT202400447T1 (it) 2024-11-15
IL272023B1 (en) 2024-08-01
IL272023B2 (en) 2024-12-01
TW201909896A (zh) 2019-03-16
BR112020000482A2 (pt) 2020-07-21
US11642339B2 (en) 2023-05-09
MD3661518T2 (ro) 2024-12-31
HUE068595T2 (hu) 2025-01-28
MX2020001217A (es) 2020-03-24
CA3069989A1 (fr) 2019-02-07
JP2022169720A (ja) 2022-11-09
UA125596C2 (uk) 2022-04-27
MA49754A (fr) 2020-06-10
ZA201908495B (en) 2021-04-28
CL2019003598A1 (es) 2020-09-21
KR20200035986A (ko) 2020-04-06
ES2991549T3 (es) 2024-12-04
JP7529952B2 (ja) 2024-08-07
AU2018309667B2 (en) 2024-08-01

Similar Documents

Publication Publication Date Title
UY35624A (es) Uso de dosis elevadas de pridopidina para tratar la enfermedad de huntington
EA201270221A1 (ru) Лечение болезни крона с применением лаквинимода
MA43817B1 (fr) Méthodes de traitement de la dépression à l'aide d'antagonistes de récepteurs de l'orexine-2
NI201100147A (es) Métodos para tratar infartos agudos de miocardio y trastornos relacionados.
AR109103A1 (es) Tratamiento de la enfermedad de fabry en pacientes no tratados y tratados previamente con ert
EA202191079A1 (ru) Способы лечения синдрома ретта с применением фенфлурамина
JP2017506624A5 (fr)
PE20150161A1 (es) Uso de laquinimod de dosis alta para el tratamiento de esclerosis multiple
MA43828A (fr) Agents thérapeutiques pour maladies neurodégénératives
JP2019530706A5 (fr)
Gittelman et al. The POTENT II randomised trial: efficacy and safety of an orodispersible vardenafil formulation for the treatment of erectile dysfunction
PH12019502651A1 (en) Use of vibegron to treat overactive bladder
MA39294B1 (fr) Polythérapie contre le cancer
EP4233850A3 (fr) Formulations de capsules
JP2016510343A5 (fr)
MA39447B1 (fr) Pirlindole ou ses sels pharmaceutiquement acceptables pour une utilisation en médecine
JP2016505050A5 (fr)
EA202193190A1 (ru) Композиция, включающая придопидин и его аналог, для лечения болезни гентингтона и ее симптомов
MA49754B1 (fr) Méthodes de traitement de symptômes de gastroparésie au moyen de velusetrag
MA39448B1 (fr) (r)-pirlindole et ses sels pharmaceutiquement acceptables destinés à un usage médical
MA45202B1 (fr) Composition pharmaceutique comprenant un antagoniste du récepteur minéralocorticoïde et son utilisation
MX2022006083A (es) Metodos para tratar afecciones relacionadas con el receptor s1p1.
MA33455B1 (fr) Otamixaban pour le traitement de patients atteints d'infarctus du myocarde sans élévation du st ages et insuffisants renaux
ZA202200331B (en) Naltrexone formulation
MX2021007324A (es) Terapia oral con acido 6,8-bis-benciltio-octanoico.