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MA45245A - Méthode de traitement de maladie intestinale inflammatoire - Google Patents

Méthode de traitement de maladie intestinale inflammatoire

Info

Publication number
MA45245A
MA45245A MA045245A MA45245A MA45245A MA 45245 A MA45245 A MA 45245A MA 045245 A MA045245 A MA 045245A MA 45245 A MA45245 A MA 45245A MA 45245 A MA45245 A MA 45245A
Authority
MA
Morocco
Prior art keywords
treatment
intestinal disease
inflammatory intestinal
inflammatory
disease
Prior art date
Application number
MA045245A
Other languages
English (en)
Inventor
Morris Barocas
Marc R Gastonguay
Maria Rosario
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of MA45245A publication Critical patent/MA45245A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA045245A 2016-06-12 2017-06-12 Méthode de traitement de maladie intestinale inflammatoire MA45245A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662349026P 2016-06-12 2016-06-12

Publications (1)

Publication Number Publication Date
MA45245A true MA45245A (fr) 2019-04-17

Family

ID=59270123

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045245A MA45245A (fr) 2016-06-12 2017-06-12 Méthode de traitement de maladie intestinale inflammatoire

Country Status (7)

Country Link
US (1) US11389533B2 (fr)
EP (1) EP3468597A1 (fr)
JP (1) JP7202893B2 (fr)
CN (1) CN109414502A (fr)
CA (1) CA3027286A1 (fr)
MA (1) MA45245A (fr)
WO (1) WO2017218434A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3581585A1 (fr) 2014-11-26 2019-12-18 Millennium Pharmaceuticals, Inc. Vedolizumab pour le traitement de la fistulisation de la maladie de crohn
CA3223332A1 (fr) * 2021-06-17 2022-12-22 Prometheus Laboratories Inc. Systemes et methodes de therapie ciblee amelioree
WO2024249568A1 (fr) * 2023-05-30 2024-12-05 Paragon Therapeutics, Inc. Compositions d'anticorps anti-intégrine alpha4beta7 et procédés d'utilisation

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3883899T3 (de) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. Geänderte antikörper.
JP3095168B2 (ja) 1988-02-05 2000-10-03 エル. モリソン,シェリー ドメイン‐変性不変部を有する抗体
EP0714409A1 (fr) 1993-06-16 1996-06-05 Celltech Therapeutics Limited Anticorps
US5840299A (en) 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US7803904B2 (en) 1995-09-01 2010-09-28 Millennium Pharmaceuticals, Inc. Mucosal vascular addressing and uses thereof
ES2290955T3 (es) 1995-02-10 2008-02-16 Millennium Pharmaceuticals, Inc. Adresinas vasculares de mucosas y sus usos.
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
US6197582B1 (en) 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
US20010046496A1 (en) 2000-04-14 2001-11-29 Brettman Lee R. Method of administering an antibody
WO2002078779A1 (fr) 2001-03-27 2002-10-10 Zeon Corporation Fil-guide medical
PL2990422T3 (pl) 2004-09-03 2018-11-30 Genentech, Inc. Humanizowani antagoniści anty-beta7 i ich zastosowania
US20070122404A1 (en) 2005-11-17 2007-05-31 O'keefe Theresa L Humanized immunoglobulin reactive with alpha4beta7 integrin
EA034783B1 (ru) 2009-03-20 2020-03-20 Эмджен Инк. Антитело-антагонист, специфичное для гетеродимера альфа4бета7
TWI698254B (zh) 2011-05-02 2020-07-11 美商千禧製藥公司 抗-α4β7抗體之調配物
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
EP3581585A1 (fr) 2014-11-26 2019-12-18 Millennium Pharmaceuticals, Inc. Vedolizumab pour le traitement de la fistulisation de la maladie de crohn
US20170360926A1 (en) 2014-12-24 2017-12-21 Millennium Pharmaceuticals, Inc. PREDICTING OUTCOME OF TREATMENT WITH AN ANTI-alpha4beta7 INTEGRIN ANTIBODY
MA41636A (fr) 2015-03-06 2018-01-09 Millennium Pharm Inc Méthode de traitement de la cholangite sclérosante primitive
PE20180509A1 (es) 2015-06-08 2018-03-09 Univ Washington Composiciones y metodos para tratar la enfermedad celiaca
IL261750B2 (en) 2016-03-14 2024-07-01 Millennium Pharm Inc Method of preventing graft versus host disease
EP3430053A1 (fr) 2016-03-14 2019-01-23 Millennium Pharmaceuticals, Inc. Méthodes de traitement ou de prévention d'une maladie du greffon contre l'hôte
US11760803B2 (en) 2016-03-24 2023-09-19 Takeda Pharmaceutical Company Limited Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
TW201735949A (zh) 2016-03-24 2017-10-16 千禧製藥公司 治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法
US10918716B2 (en) 2016-05-04 2021-02-16 Millennium Pharmaceuticals, Inc. Triple combination therapy for treating Crohn's disease

Also Published As

Publication number Publication date
US11389533B2 (en) 2022-07-19
US20190255172A1 (en) 2019-08-22
JP2019519544A (ja) 2019-07-11
WO2017218434A1 (fr) 2017-12-21
CA3027286A1 (fr) 2017-12-21
EP3468597A1 (fr) 2019-04-17
CN109414502A (zh) 2019-03-01
JP7202893B2 (ja) 2023-01-12

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