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MA45020B1 - Dérivés sulfonamides aromatiques - Google Patents

Dérivés sulfonamides aromatiques

Info

Publication number
MA45020B1
MA45020B1 MA45020A MA45020A MA45020B1 MA 45020 B1 MA45020 B1 MA 45020B1 MA 45020 A MA45020 A MA 45020A MA 45020 A MA45020 A MA 45020A MA 45020 B1 MA45020 B1 MA 45020B1
Authority
MA
Morocco
Prior art keywords
sulfonamide derivatives
aromatic sulfonamide
compounds
aromatic
prophylaxis
Prior art date
Application number
MA45020A
Other languages
English (en)
Other versions
MA45020A (fr
Inventor
Arwed Cleve
Nico Bräuer
Henrik Dahllöf
Stefan Werner
Stefanie Mesch
Simon Herbert
Markus Koch
Maren Osmers
Elizabeth Hardaker
Anton Lishchynskyi
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of MA45020A publication Critical patent/MA45020A/fr
Publication of MA45020B1 publication Critical patent/MA45020B1/fr

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Abstract

La présente invention concerne des sulfonamides aromatiques substitués de formule (i), des compositions pharmaceutiques et des associations comprenant lesdits composés, et l'utilisation desdits composés pour produire une composition pharmaceutique pour le traitement ou la prophylaxie d'une maladie.
MA45020A 2016-05-03 2017-04-26 Dérivés sulfonamides aromatiques MA45020B1 (fr)

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PCT/EP2017/059882 WO2017191000A1 (fr) 2016-05-03 2017-04-26 Dérivés sulfonamides aromatiques

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WO2018104305A1 (fr) * 2016-12-09 2018-06-14 Bayer Pharma Aktiengesellschaft Sulfamoylbenzamides
WO2018104307A1 (fr) * 2016-12-09 2018-06-14 Bayer Pharma Aktiengesellschaft Dérivés de sulfonamide aromatiques et leur utilisation en tant qu'anatagon i sts ou des modulateurs allostériques négatifs de p2x4
WO2018210729A1 (fr) * 2017-05-18 2018-11-22 Bayer Pharma Aktiengesellschaft Dérivés de sulfonamide aromatiques utilisés en tant qu'antagonistes ou modulateurs allostériques négatifs du récepteur p2x4
KR20200081445A (ko) * 2017-10-29 2020-07-07 바이엘 악티엔게젤샤프트 허혈성 졸중의 치료를 위한 방향족 술폰아미드 유도체

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