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MA39315A1 - Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique - Google Patents

Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique

Info

Publication number
MA39315A1
MA39315A1 MA39315A MA39315A MA39315A1 MA 39315 A1 MA39315 A1 MA 39315A1 MA 39315 A MA39315 A MA 39315A MA 39315 A MA39315 A MA 39315A MA 39315 A1 MA39315 A1 MA 39315A1
Authority
MA
Morocco
Prior art keywords
prevention
treatment
pyridazine derivatives
ataxic disorder
ataxic
Prior art date
Application number
MA39315A
Other languages
English (en)
Inventor
Sarah Almond
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50554599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA39315(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MA39315A1 publication Critical patent/MA39315A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne des composés de formule (i) et des sels pharmaceutiquement acceptables de ceux-ci, dans la formule (i), r1 et r2 étant tels que définis dans la description, et sont destinés à être utilisés dans la prévention ou le traitement d'un trouble ataxique.
MA39315A 2014-03-06 2015-03-06 Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique MA39315A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1403944.0A GB201403944D0 (en) 2014-03-06 2014-03-06 New use
PCT/GB2015/050654 WO2015132608A1 (fr) 2014-03-06 2015-03-06 Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique

Publications (1)

Publication Number Publication Date
MA39315A1 true MA39315A1 (fr) 2017-09-29

Family

ID=50554599

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39315A MA39315A1 (fr) 2014-03-06 2015-03-06 Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique

Country Status (32)

Country Link
US (1) US20170014407A1 (fr)
EP (1) EP3113778B1 (fr)
JP (1) JP6510549B2 (fr)
KR (1) KR20160126081A (fr)
CN (1) CN106102743A (fr)
AU (1) AU2015225954B2 (fr)
CA (1) CA2940342A1 (fr)
CL (1) CL2016002151A1 (fr)
CY (1) CY1120573T1 (fr)
DK (1) DK3113778T3 (fr)
EA (1) EA036438B1 (fr)
ES (1) ES2676905T3 (fr)
GB (1) GB201403944D0 (fr)
GE (1) GEP20196984B (fr)
HR (1) HRP20181082T1 (fr)
IL (1) IL247435A0 (fr)
LT (1) LT3113778T (fr)
MA (1) MA39315A1 (fr)
MX (1) MX2016010524A (fr)
MY (1) MY186475A (fr)
PH (1) PH12016501751A1 (fr)
PL (1) PL3113778T3 (fr)
PT (1) PT3113778T (fr)
RS (1) RS57594B1 (fr)
SG (1) SG11201607106YA (fr)
SI (1) SI3113778T1 (fr)
SM (1) SMT201800367T1 (fr)
TR (1) TR201809537T4 (fr)
TW (1) TW201534591A (fr)
UA (1) UA123352C2 (fr)
WO (1) WO2015132608A1 (fr)
ZA (1) ZA201604611B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
GB201222711D0 (en) 2012-12-17 2013-01-30 Takeda Pharmaceutical Novel compounds
CN111018790B (zh) 2014-04-29 2023-09-19 Fmc公司 哒嗪酮除草剂
TWI785022B (zh) 2017-03-28 2022-12-01 美商富曼西公司 新穎噠嗪酮類除草劑
CN111315725B (zh) 2017-06-30 2023-09-01 Fmc公司 作为除草剂的4-(3,4-二氢萘-1-基或2h-色烯-4-基)-5-羟基-2h-哒嗪-3-酮
CN112569217B (zh) * 2019-09-30 2022-04-22 厦门大学 戊酸衍生物在治疗遗传性小脑共济失调中的应用
JP2021138648A (ja) 2020-03-04 2021-09-16 武田薬品工業株式会社 経口固形製剤
AU2022228417A1 (en) 2021-03-01 2023-10-26 Neurocrine Biosciences, Inc. Use of luvadaxistat for the treatment of cognitive impairment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE321553T1 (de) * 1998-06-10 2006-04-15 Meiji Seika Kaisha Arzneimittel für hinterstrangataxie und zusammensetzung zur behandlung von hinterstrangataxie
WO2003047558A2 (fr) * 2001-12-03 2003-06-12 Genset S.A. Traitement de troubles du systeme nerveux central a l'aide d'inhibiteurs de d-amino-oxydase et de d-aspartate oxydase
JO3115B1 (ar) * 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao

Also Published As

Publication number Publication date
PL3113778T3 (pl) 2018-11-30
EP3113778A1 (fr) 2017-01-11
CY1120573T1 (el) 2019-07-10
AU2015225954B2 (en) 2020-06-18
LT3113778T (lt) 2018-08-27
ES2676905T3 (es) 2018-07-26
ZA201604611B (en) 2017-09-27
WO2015132608A1 (fr) 2015-09-11
MX2016010524A (es) 2016-10-31
CA2940342A1 (fr) 2015-09-11
GEP20196984B (en) 2019-06-25
JP2017507156A (ja) 2017-03-16
MY186475A (en) 2021-07-22
SMT201800367T1 (it) 2018-09-13
AU2015225954A1 (en) 2016-07-07
KR20160126081A (ko) 2016-11-01
SG11201607106YA (en) 2016-09-29
JP6510549B2 (ja) 2019-05-08
CL2016002151A1 (es) 2016-12-30
US20170014407A1 (en) 2017-01-19
TW201534591A (zh) 2015-09-16
RS57594B1 (sr) 2018-11-30
SI3113778T1 (en) 2018-08-31
IL247435A0 (en) 2016-11-30
PH12016501751A1 (en) 2017-02-06
CN106102743A (zh) 2016-11-09
EA036438B1 (ru) 2020-11-11
EP3113778B1 (fr) 2018-06-06
EA201691566A1 (ru) 2016-12-30
PT3113778T (pt) 2018-07-11
TR201809537T4 (tr) 2018-07-23
DK3113778T3 (en) 2018-07-30
GB201403944D0 (en) 2014-04-23
UA123352C2 (uk) 2021-03-24
HRP20181082T1 (hr) 2018-09-07

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