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MA31506B1 - Composes modulant les sirtuines - Google Patents

Composes modulant les sirtuines

Info

Publication number
MA31506B1
MA31506B1 MA32482A MA32482A MA31506B1 MA 31506 B1 MA31506 B1 MA 31506B1 MA 32482 A MA32482 A MA 32482A MA 32482 A MA32482 A MA 32482A MA 31506 B1 MA31506 B1 MA 31506B1
Authority
MA
Morocco
Prior art keywords
diseases
disorders
aging
sirtuins
compounds modulating
Prior art date
Application number
MA32482A
Other languages
Arabic (ar)
English (en)
Inventor
Jean Bemis
Jeremy S Disch
Pui Yee Ng
Christopher Oalmann
Robert B Perni
Chi B Vu
Original Assignee
Sirtris Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirtris Pharmaceuticals Inc filed Critical Sirtris Pharmaceuticals Inc
Publication of MA31506B1 publication Critical patent/MA31506B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux composés modulant les sirtuines et leurs méthodes d'utilisation. Ces composés modulant les sirtuines peuvent être utilisés pour prolonger la durée de vie d'une cellule et pour traiter et/ou prévenir un grand nombre de maladies et de troubles, y compris, par exemple, des maladies et des troubles liés au vieillissement et au stress, le diabète, l'obésité, des maladies neurodégénératives, une maladie cardiovasculaire, des troubles de la coagulation sanguine, l'inflammation, le cancer, et/ou les bouffées vasomotrices, ainsi que des maladies ou des troubles pouvant bénéficier d'une activité mitochondriale plus intense. L'invention concerne également des compositions comprenant un composé modulant les sirtuines, combiné à un autre agent thérapeutique.
MA32482A 2007-06-20 2010-01-07 Composes modulant les sirtuines MA31506B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93663607P 2007-06-20 2007-06-20
PCT/US2008/007776 WO2008156869A2 (fr) 2007-06-20 2008-06-20 Composés modulant les sirtuines

Publications (1)

Publication Number Publication Date
MA31506B1 true MA31506B1 (fr) 2010-07-01

Family

ID=39798234

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32482A MA31506B1 (fr) 2007-06-20 2010-01-07 Composes modulant les sirtuines

Country Status (23)

Country Link
US (2) US7893086B2 (fr)
EP (1) EP2170905A2 (fr)
JP (1) JP5498940B2 (fr)
KR (1) KR20100051048A (fr)
CN (2) CN103833775A (fr)
AR (1) AR067107A1 (fr)
AU (1) AU2008266749C1 (fr)
BR (1) BRPI0813651A2 (fr)
CA (1) CA2691733A1 (fr)
CL (1) CL2008001822A1 (fr)
CO (1) CO6251248A2 (fr)
CR (1) CR11232A (fr)
DO (1) DOP2009000284A (fr)
EA (1) EA018922B1 (fr)
IL (1) IL202730A0 (fr)
MA (1) MA31506B1 (fr)
MX (1) MX2009013977A (fr)
NZ (1) NZ581990A (fr)
PE (1) PE20090694A1 (fr)
TW (1) TW200916472A (fr)
UY (1) UY31169A1 (fr)
WO (1) WO2008156869A2 (fr)
ZA (1) ZA200908883B (fr)

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AR067107A1 (es) 2009-09-30
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MX2009013977A (es) 2010-04-09
IL202730A0 (en) 2010-06-30
US7893086B2 (en) 2011-02-22
TW200916472A (en) 2009-04-16
AU2008266749B2 (en) 2012-03-15
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ZA200908883B (en) 2010-08-25
CA2691733A1 (fr) 2008-12-24
KR20100051048A (ko) 2010-05-14
CO6251248A2 (es) 2011-02-21
AU2008266749A1 (en) 2008-12-24
UY31169A1 (es) 2009-01-30
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US20110152254A1 (en) 2011-06-23
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US8268862B2 (en) 2012-09-18
CR11232A (es) 2010-05-24
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JP2010530432A (ja) 2010-09-09
PE20090694A1 (es) 2009-06-20
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DOP2009000284A (es) 2010-02-28

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