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MA26609A1 - Derives de retiferol, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation - Google Patents

Derives de retiferol, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation

Info

Publication number
MA26609A1
MA26609A1 MA25470A MA25470A MA26609A1 MA 26609 A1 MA26609 A1 MA 26609A1 MA 25470 A MA25470 A MA 25470A MA 25470 A MA25470 A MA 25470A MA 26609 A1 MA26609 A1 MA 26609A1
Authority
MA
Morocco
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
retiferol derivatives
retiferol
Prior art date
Application number
MA25470A
Other languages
English (en)
Inventor
Barbier Pierre
Bauer Franz
Muller Marc
Mohr Peter
Pirson Wolfgang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26609A1 publication Critical patent/MA26609A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/02Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/19Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/263Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/273Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA25470A 1998-02-26 1999-02-22 Derives de retiferol, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation MA26609A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98103346 1998-02-26

Publications (1)

Publication Number Publication Date
MA26609A1 true MA26609A1 (fr) 2004-12-20

Family

ID=8231480

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25470A MA26609A1 (fr) 1998-02-26 1999-02-22 Derives de retiferol, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation

Country Status (21)

Country Link
US (1) US6184422B1 (fr)
EP (1) EP1056716B1 (fr)
JP (1) JP3507435B2 (fr)
KR (1) KR20010041313A (fr)
CN (1) CN1133621C (fr)
AR (1) AR018120A1 (fr)
AT (1) ATE229503T1 (fr)
AU (1) AU751241B2 (fr)
BR (1) BR9908315A (fr)
CA (1) CA2320180C (fr)
CO (1) CO4980898A1 (fr)
DE (1) DE69904442T2 (fr)
DK (1) DK1056716T3 (fr)
ES (1) ES2188134T3 (fr)
MA (1) MA26609A1 (fr)
MY (1) MY133520A (fr)
PE (1) PE20000267A1 (fr)
PT (1) PT1056716E (fr)
TR (1) TR200002477T2 (fr)
WO (1) WO1999043646A1 (fr)
ZA (1) ZA991550B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145712A0 (en) * 1999-04-01 2002-07-25 Esperion Therapeutics Inc Ether compounds, compositions, and uses thereof
EP1094060B1 (fr) * 1999-10-18 2004-04-28 Basilea Pharmaceutica AG Procédé pour la préparation de dérivés de rétiférol
US6310262B1 (en) 1999-10-18 2001-10-30 Basilea Pharmaceutica Ag Process for preparing retiferol derivatives
BR0115560A (pt) * 2000-11-22 2003-08-19 Hoffmann La Roche Compostos, composição farmacêutica, processo para preparar compostos, processo para tratamento ou prevenção de enfermiidades hiperproliferantes da pele, processo para reverter as condições associadas com fotodanos
JPWO2003055854A1 (ja) * 2001-12-26 2005-05-12 中外製薬株式会社 2位に置換基を有するビタミンd誘導体
US6723755B2 (en) 2002-06-12 2004-04-20 Piotr Chomczynski Method of treating rosacea
US7812057B2 (en) * 2004-08-25 2010-10-12 Molecular Research Center, Inc. Cosmetic compositions
CA2620354C (fr) * 2005-08-30 2013-02-05 Wisconsin Alumni Research Foundation Analogues des-c,d d'1.alpha.,25-dihydroxy-19-norvitamine d3
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
MX2010007956A (es) * 2008-01-22 2010-09-14 Wisconsin Alumni Reasearch Fou Analogos de 13,13-dimetil-des-c,d de compuestos de 1a,25-dihidroxi-19-nor-vitamina d3 y formas de dosificacion de composicion topica y metodos de tratamiento de condiciones de la piel.
KR20170096238A (ko) * 2009-01-27 2017-08-23 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 d3 및 이의 유사물
CN106265695B (zh) 2009-08-14 2021-05-07 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN114044788A (zh) * 2021-08-12 2022-02-15 甘肃皓天医药科技有限责任公司 一种氟骨化醇cd环的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103755C (zh) 1993-07-09 2003-03-26 桑拉米克斯实验公司 维生素d的新型结构类似物
PL174912B1 (pl) 1994-01-24 1998-10-30 Inst Farmaceutyczny Nowe związki farmakologicznie czynne z grupy witamin D i sposób ich otrzymywania
US5461116A (en) 1994-11-10 1995-10-24 Shell Oil Company Core functionalized star block copolymers
CA2288629A1 (fr) * 1997-05-23 1998-11-26 F. Hoffmann-La Roche Ag Derives cyclohexanediol

Also Published As

Publication number Publication date
ATE229503T1 (de) 2002-12-15
DE69904442T2 (de) 2003-09-25
US6184422B1 (en) 2001-02-06
AU751241B2 (en) 2002-08-08
CN1291974A (zh) 2001-04-18
ZA991550B (en) 1999-08-26
KR20010041313A (ko) 2001-05-15
JP3507435B2 (ja) 2004-03-15
JP2002504537A (ja) 2002-02-12
ES2188134T3 (es) 2003-06-16
EP1056716A1 (fr) 2000-12-06
BR9908315A (pt) 2000-11-07
PT1056716E (pt) 2003-04-30
CA2320180C (fr) 2005-06-07
CO4980898A1 (es) 2000-11-27
AU2624699A (en) 1999-09-15
DE69904442D1 (en) 2003-01-23
MY133520A (en) 2007-11-30
TR200002477T2 (tr) 2001-03-21
DK1056716T3 (da) 2003-04-07
CN1133621C (zh) 2004-01-07
EP1056716B1 (fr) 2002-12-11
AR018120A1 (es) 2001-10-31
CA2320180A1 (fr) 1999-09-02
PE20000267A1 (es) 2000-04-10
WO1999043646A1 (fr) 1999-09-02

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