LV12037B - Zobu pasta - Google Patents

Abstract

The toothpaste contains a complex of remodent, natrium monofluoric phosphate and herb essences. The toothpaste has a medically preventive resolvent effect.

Description

ZO&U MAIL

The present invention relates to the field of medicine, in particular to prophylactic treatment pastes.

Peppermint Toothpaste, VS 7983-70, is known to contain chalk, glycerol, sodium carboxymethylcellulose, perfumery oil, sodium lauryl sulfate, sodium benzoate, saccharin and a perfume composition.

Of the known toothpastes the technically closest to be applied is the toothpaste (Aut. U.S. Pat. No. 1003415, SIK 5 A61K7 / 16, subd. 20. 11. 80.), which contains mineral oil, chalk, polyatomic alcohol, sodium carboxymethylcellulose, sodium. lauryl sulphate, preservatives, flavoring agent, perfume composition, buffer, silica hydrate, remodent and water, containing glycerol as the polyhydric alcohol and sodium benzoate as the preservative oil.

However, the anti-caries and anti-inflammatory effects of existing toothpastes are not effective enough.

In the present invention, a toothpaste composition comprising chalk, polyhydric alcohol, sodium carboxymethylcellulose, mineral oil, sodium laurysulfate, preservative, flavoring agent, perfume composition, buffer, silica hydrate, remodent and water containing sorbitol as a mineral, medicinal or perfumery oil, as a preservative - paraform, as a buffer solution - of sodium carbonate and sodium hydrogen carbonate solution, supplemented with sodium monofluorophosphate and plant extracts of calendula, rosehip, rowanberry or St. John's wort, and clove. The components are in the following weight ratios,%:

Sorbitol, 70% aqueous solution 20.0 -26.0 Sodium carboxymethylcellulose 1.0 to 1.5 Paraforms 0.05 - 0.1 Chalk 33.0 - 38.0 Sodium carbonate 0.01 - 0.02 Sodium hydrogen carbonate 0.01 - 0.03 Silica hydrate 1.5 - 2.5 Remodents 0.8 - 1.2 Sodium monofluorophosphate 0.4-1.2 Saccharin 0.05 - 0.2 White medicinal or perfumery oil 0, o -1,2

Herbal Extract Perfume Composition Sodium Lauric Sulphate Water

0.3 - 0.8 0.8 -1.2 1.5-2.0 others

The toothpaste on offer has good cleaning, anti-caries and anti-inflammatory properties, which are determined by a specially selected high activity complex consisting of sodium monofluorophosphate, remodent and herbal extract.

The active part of sodium monofluorophosphate is the active ion of the flora (F), while the active part of the remodent is the calcium and phosphate ions.

Remodent - anti-caries agent containing calcium, orthophosphoric acid anion, sodium, potassium, magnesium, trace elements, water soluble proteins, citrate compound.

Calendula extract has anti-inflammatory, antiseptic, antispasmodic effect and promotes healing of scars. Basic components: carotenoids, lycopene, rubixantin, triterpene glycosides, resin.

Calendula extract can be replaced by rosehip, rowan or St. John's wort extract, or clove and carrot seed carbonic acid extract.

The combination of the aforementioned components provides toothpaste with good cleaning, anti-inflammatory and anti-caries properties.

Preparation of a suitable toothpaste.

Sorbitol, sodium carboxymethylcellulose, saccharin, paraform, sodium carbonate, sodium hydrogen carbonate, remodent and sodium monophthalophosphate are placed in a vessel and stirred for 25-30 minutes. Then add cold water to the mixture, turn on the heating, stir for 8-10 minutes under vacuum and homogenize for 15-20 minutes. Stop heating at 25 ° C; to the prepared gel is added portions of silica hydrate under vacuum pressure. Chalk is then added in portions over 40 minutes and the components dispersed under vacuum for 10-15 minutes. Then add white medicinal oil, stir for 5-8 minutes, add herbal extract and perfume composition, stir for another 5 minutes, then add sodium laurysulfate. The components are stirred for 5-8 minutes, homogenized under vacuum for 35-40 minutes. Mass cooling to 35 ⁰ C.

The following is an example of how to make a toothpaste.

Example 1: The amount of ingredients is calculated to make 100 kg of toothpaste:

Sorbitol, 70% aqueous solution 24.0 Sodium carboxymethylcellulose 1/2 Paraforms 0.1 Chalk 36.0 Sodium carbonate 0.01 Sodium hydrogen carbonate 0.02 Remodents 1.1 Sodium monofluorophosphate 0.7 Silica hydrate 2.0 Saccharin 0.1 White medicinal oil 1.0 Calendula extract 0.4 Sodium lauryl sulphate 1.7 Perfume composition 1/0 Water 30.67

The physical-chemical characteristics of the toothpaste produced are as follows:

appearance - homogeneous paste-free mass;

color - white to yellowish;

odor - according to the standard (mint);

taste - pleasant, fresh;

foam number, circus - 525;

foam stability,% - 0.3;

hydrogen ion concentration, pH (in 20% aqueous solution) - 9.0

Example 2. The amount of the ingredients is calculated to make 100 kg of toothpaste.

Sorbitol, 70% aqueous solution Carboxymethylcellulose sodium Paraform

20.0

1.5

0.05

Chalk 38.0 Sodium carbonate 0.01 Sodium hydrogen carbonate 0.01 Remodents 0.8 Sodium monofluorophosphate 1.2 Silica hydrate 1.5 Sodium saccharate 0.05 White medicinal oil 0.5 Rosehip extract 0.3 Sodium lauryl sulphate 2.0 Perfume composition 0.8 Water 33.28

The physical-chemical characteristics of the toothpaste produced are as follows:

external appearance - homogeneous paste-free mass;

color - white to yellowish;

odor - according to the standard (mint);

taste - pleasant, fresh;

foam number, cm ³ - 525;

foam stability,% - 0.3;

hydrogen ion concentration, pH (in 20% aqueous solution) - 9.2

Example 3. The amount of the ingredients is calculated to make 100 kg of toothpaste.

Sorbitol, 70% aqueous solution 26.0 Sodium carboxymethylcellulose 1.0 Paraforms 0.1 Chalk 33.0 Sodium carbonate 0.02 Sodium hydrogen carbonate 0.03 Remodents 1.2 Sodium monofluorophosphate 0.4 Silica hydrate 2.5 Saccharin 0.1 Perfumery oil 1.2 St. John's wort extract 0.8 Sodium lauryl sulphate 1.5 Perfume composition 1.2 Water 30.00

The physical-chemical characteristics of the toothpaste produced are as follows:

external appearance - homogeneous paste-free mass;

color - white to yellowish;

odor - according to the standard (mint);

taste - pleasant, fresh;

foam number, cm ^ - 500;

foam stability,% - 0.6;

hydrogen ion concentration, pH (in 20% aqueous solution) - 8.8 (according to technical requirements 09.2 / 08.08-96 and GOST 7983-82 “Toothpastes”).

The offered toothpaste was tested at the Latvian Academy of Medicine. As a result of the approbation, the toothpaste showed good cleaning properties, as evidenced by a 74.4% decrease in the hygiene index and a 79.3% decrease in the color intensity index, as well as a pronounced anti-inflammatory properties confirmed by a 91.5% decrease in the PMA index. . The effectiveness of the anti-caries effect is demonstrated by a 37-43% reduction in dental caries growth. No allergic or other adverse effects were observed. Toothpaste is an effective anti-inflammatory and anti-caries treatment.

Claims (1)

1. Toothpaste containing chalk, polyhydric alcohol, sodium carboxymethylcellulose, mineral oil, sodium lauryl sulfate, preservative, flavoring, perfume composition, buffer, silica hydrate, remodent and water, other than that as a sorbitol alcohol , as mineral oil - white medicinal or perfumery oil, as a preservative - paraform, as a buffer solution - sodium carbonate and sodium bicarbonate solution, supplemented with sodium monofluorophosphate and plant extracts - calendula, rosehip, rowan or celandine, and clove, , in the following mass ratios,% Sorbitol, 70% aqueous solution 20.0-26.0 Sodium carboxymethylcellulose 1.0-1.5 Paraforms 0.05-0 _z l Chalk 33.0-38.0 Sodium carbonate 0.01-0.02 Sodium hydrogen carbonate 0.01-0.03 Silica hydrate 1.5-2.5 Remodents 0.8-1.2 Sodium monofluorophosphate 0.4-1.2 Saccharin 0.05-0.2 White medicinal or perfumery oil 0.5-1.2 Plant extract 0.3-0.8 Perfume composition 0.8-1.2 Sodium laurisulphate 1.5-2.0 Water the rest of