LTIP1713A - Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use - Google Patents

Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use

Info

Publication number: LTIP1713A
Authority: LT; Lithuania
Prior art keywords: dialkoxy; pyridinyl; preparation; pharmaceutical use; benzimidazole derivatives
Prior art date: 1990-06-20

Application number

LTIP1713A

Inventor

Arne Elof Braendstroem

Per Lennart Lindberg

Gunnel Elisabeth Sunden

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-20

Filing date

1993-12-30

Publication date

1995-08-25

1993-12-30 Application filed by Astra Ab filed Critical Astra Ab

1995-08-25 Publication of LTIP1713A publication Critical patent/LTIP1713A/en

1996-06-25 Publication of LT3977B publication Critical patent/LT3977B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

LTIP1713A 1990-06-20 1993-12-30 Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use LT3977B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9002206A SE9002206D0 (en)	1990-06-20	1990-06-20	NEW COMPOUNDS

Publications (2)

Publication Number	Publication Date
LTIP1713A true LTIP1713A (en)	1995-08-25
LT3977B LT3977B (en)	1996-06-25

Family

ID=20379831

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LTIP1712A LT3952B (en)	1990-06-20	1993-12-30	Substituted benzimidazoles, process for their preparation and their pharmaceutical use
LTIP1713A LT3977B (en)	1990-06-20	1993-12-30	Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
LTIP1712A LT3952B (en)	1990-06-20	1993-12-30	Substituted benzimidazoles, process for their preparation and their pharmaceutical use

Country Status (27)

Country	Link
EP (1)	EP0535081A1 (en)
JP (1)	JPH05507713A (en)
CN (1)	CN1058212A (en)
AP (1)	AP215A (en)
AU (1)	AU649453B2 (en)
BG (1)	BG97200A (en)
CA (1)	CA2083714A1 (en)
CZ (1)	CZ279772B6 (en)
FI (1)	FI925766A (en)
HU (1)	HUT62881A (en)
IE (1)	IE912025A1 (en)
IL (1)	IL98470A0 (en)
IS (1)	IS3721A7 (en)
LT (2)	LT3952B (en)
LV (1)	LV10953A (en)
MA (1)	MA22199A1 (en)
NO (1)	NO924775L (en)
NZ (1)	NZ238546A (en)
OA (1)	OA09682A (en)
PT (1)	PT98035A (en)
RO (1)	RO110493B1 (en)
SE (1)	SE9002206D0 (en)
TN (1)	TNSN91049A1 (en)
TW (1)	TW216418B (en)
WO (1)	WO1991019711A1 (en)
YU (1)	YU104191A (en)
ZA (2)	ZA914296B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9002043D0 (en) *	1990-06-07	1990-06-07	Astra Ab	IMPROVED METHOD FOR SYNTHESIS
SE9103776D0 (en) *	1991-12-19	1991-12-19	Astra Ab	NEW COMPOUNDS
IS4232A (en) *	1993-12-06	1995-06-07	Astra Aktiebolag	Substituted benzimidazole, its methods of manufacture and pharmacological use
SE9500422D0 (en) *	1995-02-06	1995-02-06	Astra Ab	New oral pharmaceutical dosage forms
SE9500478D0 (en) *	1995-02-09	1995-02-09	Astra Ab	New pharmaceutical formulation and process
SE9600070D0 (en)	1996-01-08	1996-01-08	Astra Ab	New oral pharmaceutical dosage forms
EP1257269B1 (en)	2000-02-24	2004-11-03	Kopran Research Laboratories Limited	Orally administrable acid stable anti-ulcer benzimidazole derivatives
SE0101379D0 (en)	2001-04-18	2001-04-18	Diabact Ab	Composition that inhibits gastric acid secretion
US8206741B2 (en)	2001-06-01	2012-06-26	Pozen Inc.	Pharmaceutical compositions for the coordinated delivery of NSAIDs
DE60325709D1 (en)	2002-04-09	2009-02-26	Flamel Tech Sa	ORAL AQUEOUS SUSPENSION CONTAINING MICRO CAPSULES FOR THE CONTROLLED RELEASE OF ACTIVE SUBSTANCES
SE0203065D0 (en)	2002-10-16	2002-10-16	Diabact Ab	Gastric acid secretion inhibiting composition
US8246986B2 (en)	2003-09-26	2012-08-21	Alza Corporation	Drug coating providing high drug loading
TW200606163A (en)	2004-04-22	2006-02-16	Eisai Co Ltd	Imidazopyridine compound
US8541026B2 (en)	2004-09-24	2013-09-24	Abbvie Inc.	Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en) *	2005-04-15	2007-01-18	Eisai Co., Ltd.	Benzimidazole compound
US9040564B2 (en)	2005-04-28	2015-05-26	Eisai R&D Management Co., Ltd.	Stabilized composition
US7981908B2 (en)	2005-05-11	2011-07-19	Vecta, Ltd.	Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en)	2005-05-11	2010-09-28	Vecta, Ltd.	Composition and methods for inhibiting gastric acid secretion
WO2007122686A1 (en) *	2006-04-14	2007-11-01	Eisai R & D Management Co., Ltd.	Benzimidazole compounds
JP5474541B2 (en)	2006-07-25	2014-04-16	ベクタ・リミテッド	Compositions and methods for inhibiting gastric acid secretion using PPI in combination with small dicarboxylic acid derivatives
WO2008047681A1 (en) *	2006-10-13	2008-04-24	Eisai R & D Management Co., Ltd.	Benzimidazole compound having gastric acid secretion inhibitory activity
CN102209529A (en)	2008-09-09	2011-10-05	阿斯利康(瑞典)有限公司	Method for delivering a pharmaceutical composition to patient in need thereof
JP2012531409A (en)	2009-06-25	2012-12-10	アストラゼネカ・アクチエボラーグ	Methods for treating patients at risk of developing NSAID-related ulcers
WO2011080501A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en)	2011-12-05	2013-06-12	Abo Bakr Mohammed Ali Al-Mehdar	Fixed-dose combination for treatment of helicobacter pylori associated diseases
EA028049B1 (en)	2011-12-28	2017-10-31	Поузен Инк.	Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
IL307576B1 (en) *	2016-09-14	2025-02-01	Yufeng Jane Tseng	Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (en)	1974-02-18	1981-07-06	Haessle Ab	ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects
SE416649B (en)	1974-05-16	1981-01-26	Haessle Ab	PROCEDURE FOR THE PREPARATION OF SUBSTANCES WHICH PREVENT Gastric acid secretion
IN148930B (en)	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (en)	1978-04-14	1979-10-15	Haessle Ab	Gastric acid secretion
US4359465A (en)	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (en)	1980-08-21	1984-07-13	Hoffmann La Roche	IMIDAZOLE DERIVATIVES.
SE8300736D0 (en)	1983-02-11	1983-02-11	Haessle Ab	NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS
SE8301182D0 (en)	1983-03-04	1983-03-04	Haessle Ab	NOVEL COMPOUNDS
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) *	1984-10-31	1988-08-31	Byk Gulden Lomberg Chem Fab	Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US4738975A (en)	1985-07-02	1988-04-19	Takeda Chemical Industries, Ltd.	Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (en) *	1985-10-29	1985-10-29	Haessle Ab	NOVEL PHARMACOLOGICAL COMPOUNDS
NZ222495A (en)	1986-11-21	1991-04-26	Haessle Ab	Benzimidazole derivatives and pharmaceutical compositions
DE3722810A1 (en) *	1987-07-10	1989-01-19	Hoechst Ag	SUBSTITUTED BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THE USE THEREOF
AU2621888A (en) *	1987-10-30	1989-05-23	Aktiebolaget Hassle	Omeprazole for treatment of diseases related to bone loss
ZA889194B (en) *	1987-12-11	1989-08-30	Byk Gulden Lomberg Chemisch Fa	Novel benzimidazole derivatives
WO1989011479A1 (en) *	1988-05-25	1989-11-30	Byk Gulden Lomberg Chemische Fabrik Gmbh	New fluoralkoxy compounds

1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/en unknown
1991
- 1991-06-05 ZA ZA914296A patent/ZA914296B/en unknown
- 1991-06-05 ZA ZA914297A patent/ZA914297B/en unknown
- 1991-06-11 JP JP91511435A patent/JPH05507713A/en active Pending
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/en not_active Application Discontinuation
- 1991-06-11 CA CA002083714A patent/CA2083714A1/en not_active Abandoned
- 1991-06-11 RO RO92-01581A patent/RO110493B1/en unknown
- 1991-06-11 HU HU924033A patent/HUT62881A/en unknown
- 1991-06-11 EP EP91911659A patent/EP0535081A1/en not_active Withdrawn
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-12 YU YU104191A patent/YU104191A/en unknown
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 IL IL98470A patent/IL98470A0/en unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/en unknown
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/en unknown
- 1991-06-19 PT PT98035A patent/PT98035A/en not_active Application Discontinuation
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-20 CN CN91105024A patent/CN1058212A/en active Pending
- 1991-06-20 IS IS3721A patent/IS3721A7/en unknown
- 1991-06-20 CZ CS911894A patent/CZ279772B6/en unknown
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO92924775A patent/NO924775L/en unknown
- 1992-12-18 BG BG097200A patent/BG97200A/en unknown
- 1992-12-18 FI FI925766A patent/FI925766A/en not_active Application Discontinuation
1993
- 1993-08-27 LV LV931045A patent/LV10953A/en unknown
- 1993-12-30 LT LTIP1712A patent/LT3952B/en not_active IP Right Cessation
- 1993-12-30 LT LTIP1713A patent/LT3977B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
CS189491A3 (en)	1992-04-15
WO1991019711A1 (en)	1991-12-26
CN1058212A (en)	1992-01-29
AP9100285A0 (en)	1991-07-31
RO110493B1 (en)	1996-01-30
BG97200A (en)	1993-12-24
FI925766A0 (en)	1992-12-18
TNSN91049A1 (en)	1992-10-25
NO924775D0 (en)	1992-12-10
NZ238546A (en)	1994-03-25
AU8009791A (en)	1992-01-07
ZA914297B (en)	1992-03-25
TW216418B (en)	1993-11-21
YU104191A (en)	1994-01-20
JPH05507713A (en)	1993-11-04
AP215A (en)	1992-09-02
IL98470A0 (en)	1992-07-15
OA09682A (en)	1993-05-15
IS3721A7 (en)	1991-12-21
IE912025A1 (en)	1992-01-01
FI925766A (en)	1992-12-18
LV10953A (en)	1995-12-20
PT98035A (en)	1992-03-31
HUT62881A (en)	1993-06-28
AU649453B2 (en)	1994-05-26
ZA914296B (en)	1992-03-25
MA22199A1 (en)	1992-04-01
SE9002206D0 (en)	1990-06-20
CA2083714A1 (en)	1991-12-21
HU9204033D0 (en)	1993-03-29
LTIP1712A (en)	1995-08-25
LT3952B (en)	1996-05-27
CZ279772B6 (en)	1995-06-14
EP0535081A1 (en)	1993-04-07
LT3977B (en)	1996-06-25
NO924775L (en)	1992-12-10

Publication	Publication Date	Title
IL98472A0 (en)	1992-07-15	Dialkoxy-pyridinyl-benzimidazole derivatives,process for their preparation and their pharmaceutical use
ZA914296B (en)	1992-03-25	Dialkoxy-pyridinyl-benzimidazole derivatives,process for their preparation and their pharmaceutical use
ZA916583B (en)	1992-05-27	3-amidopyrazole derivatives,process for preparing these and pharmaceutical compositions containing them
EP0412848A3 (en)	1991-04-10	Quinoline derivatives, process for their preparation and their use as medicaments
CS210291A3 (en)	1992-02-19	Benzeneacetamide derivatives, process for their preparation and pharmaceuticals based on them
LTIP709A (en)	1995-01-31	Sbstituted corticoid-17-alkylcarbonates, process for preparing thereof and pharmaceutical preparations
IL98864A0 (en)	1992-07-15	Oxazolyl derivatives,process for their preparation and pharmaceutical compositions containing them
HU9202864D0 (en)	1992-11-30	Gycinamide derivatives, their production and pharmaceutical preparatives containing them
EP0449026A3 (en)	1992-05-06	Desoxynojirimycin derivatives, process for their preparation and their use in drugs
GB2240104B (en)	1993-08-11	New arylvinylamide derivatives and process for their preparation
GB8917687D0 (en)	1989-09-20	Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
IL98812A0 (en)	1992-07-15	Purine derivatives,process for their preparation and pharmaceutical compositions containing them
CS265391A3 (en)	1992-03-18	Novel thienodiazepines, process for their preparation and pharmaceutical comprising them
IL97656A0 (en)	1992-06-21	Purine derivatives,process for their preparation and pharmaceutical compositions comprising them
GB9116896D0 (en)	1991-09-18	3-deoxymannosamine derivatives and process for their preparation
LTIP760A (en)	1994-05-15	Novel thienothiazine derivatives, process for preparing thereof and pharmaceutical preparations
HUT66140A (en)	1994-09-28	New 2-spirocyclopropyl-cephalosporin-sulfone derivatives and process for the preparation thereof
IL97859A0 (en)	1992-06-21	1,5-benzothiazepinone derivatives,their preparation and pharmaceutical use
EP0488009A3 (en)	1992-08-19	Piperidinoalkyl-benzoxazine-and-thiazine-compounds, processes for their preparation and drugs containing them
GB2234748B (en)	1993-06-30	Quinoline derivatives, process for their preparation and their use as medicaments
EP0583698A3 (en)	1995-02-15	Deoxycyclitol derivatives, process for their preparation and their use in medicaments.
EP0474590A3 (en)	1993-04-21	Taurine derivatives, process for their preparation and their use
GB9119714D0 (en)	1991-10-30	Trifluoromethylketone derivatives, process for preparation thereof and use thereof
IL88817A0 (en)	1989-07-31	Phenoxypropanolamine derivatives,process for their preparation and pharmaceutical compositions comprising them
GB9116131D0 (en)	1991-09-11	Fr901460 substance,process for preparation thereof and use thereof

Legal Events

Date	Code	Title	Description
1997-07-25	MM9A	Lapsed patents	Effective date: 19961230