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LT3442535T - Heterocikliniai junginiai kaip ret kinazės inhibitoriai - Google Patents

Heterocikliniai junginiai kaip ret kinazės inhibitoriai

Info

Publication number
LT3442535T
LT3442535T LTEPPCT/GB2017/051077T LTGB2017051077T LT3442535T LT 3442535 T LT3442535 T LT 3442535T LT GB2017051077 T LTGB2017051077 T LT GB2017051077T LT 3442535 T LT3442535 T LT 3442535T
Authority
LT
Lithuania
Prior art keywords
kinase inhibitors
heterocyclic compounds
ret kinase
ret
heterocyclic
Prior art date
Application number
LTEPPCT/GB2017/051077T
Other languages
English (en)
Inventor
Allan Jordan
Rebecca NEWTON
Bohdan Waszkowycz
Jonathan Sutton
George Hynd
Silvia PAOLETTA
Euan Alexander Fraser Fordyce
Original Assignee
Cancer Research Technology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Technology Limited filed Critical Cancer Research Technology Limited
Publication of LT3442535T publication Critical patent/LT3442535T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
LTEPPCT/GB2017/051077T 2016-04-15 2017-04-18 Heterocikliniai junginiai kaip ret kinazės inhibitoriai LT3442535T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201606635 2016-04-15
PCT/GB2017/051077 WO2017178845A1 (en) 2016-04-15 2017-04-18 Heterocyclic compounds as ret kinase inhibitors

Publications (1)

Publication Number Publication Date
LT3442535T true LT3442535T (lt) 2022-10-25

Family

ID=58633036

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/GB2017/051077T LT3442535T (lt) 2016-04-15 2017-04-18 Heterocikliniai junginiai kaip ret kinazės inhibitoriai

Country Status (13)

Country Link
US (3) US10844067B2 (lt)
EP (2) EP3442535B1 (lt)
DK (1) DK3442535T3 (lt)
ES (1) ES2925698T3 (lt)
HR (1) HRP20221051T8 (lt)
HU (1) HUE060082T2 (lt)
LT (1) LT3442535T (lt)
PL (1) PL3442535T3 (lt)
PT (1) PT3442535T (lt)
RS (1) RS63609B1 (lt)
SI (1) SI3442535T1 (lt)
SM (1) SMT202200348T1 (lt)
WO (1) WO2017178845A1 (lt)

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Also Published As

Publication number Publication date
SI3442535T1 (sl) 2023-01-31
HUE060082T2 (hu) 2023-01-28
US20190263819A1 (en) 2019-08-29
RS63609B1 (sr) 2022-10-31
SMT202200348T1 (it) 2022-11-18
PT3442535T (pt) 2022-09-05
WO2017178845A1 (en) 2017-10-19
US20210047334A1 (en) 2021-02-18
US10844067B2 (en) 2020-11-24
ES2925698T3 (es) 2022-10-19
US11661423B2 (en) 2023-05-30
PL3442535T3 (pl) 2022-10-24
US20240116938A1 (en) 2024-04-11
HRP20221051T8 (hr) 2023-07-21
HRP20221051T1 (hr) 2023-03-03
EP3442535A1 (en) 2019-02-20
EP3442535B1 (en) 2022-06-01
EP4104837A2 (en) 2022-12-21
EP4104837A3 (en) 2023-04-26
DK3442535T3 (da) 2022-09-05

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