LT2945647T - Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai - Google Patents
Imunogeniniai wt-1 peptidai ir jų panaudojimo būdaiInfo
- Publication number
- LT2945647T LT2945647T LTEP14741142.5T LT14741142T LT2945647T LT 2945647 T LT2945647 T LT 2945647T LT 14741142 T LT14741142 T LT 14741142T LT 2945647 T LT2945647 T LT 2945647T
- Authority
- LT
- Lithuania
- Prior art keywords
- immunogenic
- peptides
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361752799P | 2013-01-15 | 2013-01-15 | |
PCT/US2014/011711 WO2014113490A2 (en) | 2013-01-15 | 2014-01-15 | Immunogenic wt-1 peptides and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2945647T true LT2945647T (lt) | 2021-02-25 |
Family
ID=51210182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP14741142.5T LT2945647T (lt) | 2013-01-15 | 2014-01-15 | Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai |
Country Status (18)
Country | Link |
---|---|
US (1) | US9919037B2 (lt) |
EP (2) | EP3769782A1 (lt) |
JP (4) | JP6486278B2 (lt) |
CN (4) | CN116789792A (lt) |
AU (4) | AU2014207615B2 (lt) |
CA (1) | CA2898099A1 (lt) |
CY (1) | CY1123563T1 (lt) |
DK (1) | DK2945647T3 (lt) |
ES (1) | ES2832546T3 (lt) |
HR (1) | HRP20201867T1 (lt) |
HU (1) | HUE052541T2 (lt) |
LT (1) | LT2945647T (lt) |
PL (1) | PL2945647T3 (lt) |
PT (1) | PT2945647T (lt) |
RS (1) | RS61173B1 (lt) |
SI (1) | SI2945647T1 (lt) |
SM (1) | SMT202000677T1 (lt) |
WO (1) | WO2014113490A2 (lt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1951281B1 (en) | 2005-10-17 | 2015-04-15 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
EP3117836A1 (en) | 2006-04-10 | 2017-01-18 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and uses thereof |
JP6282598B2 (ja) | 2012-01-13 | 2018-02-21 | メモリアル スローン ケタリング キャンサー センター | 免疫原性wt1ペプチド及びその使用方法 |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
LT2945647T (lt) | 2013-01-15 | 2021-02-25 | Memorial Sloan Kettering Cancer Center | Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai |
WO2015168379A2 (en) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
FR3030573B1 (fr) | 2014-12-18 | 2021-06-11 | Veolia Proprete | Biostimulation in-situ de l'hydrolyse de la matiere organique pour optimiser sa valorisation energetique |
HRP20220994T1 (hr) | 2015-11-20 | 2022-11-11 | Memorial Sloan Kettering Cancer Center | Sastav za liječenje raka |
CN109072197A (zh) | 2016-02-06 | 2018-12-21 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
AU2017247607B2 (en) * | 2016-04-06 | 2021-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against AML and other cancers |
CN116970060A (zh) | 2016-12-22 | 2023-10-31 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
JP2020514375A (ja) | 2017-03-15 | 2020-05-21 | キュー バイオファーマ, インコーポレイテッド | 免疫応答を調節するための方法 |
WO2018183980A2 (en) * | 2017-03-31 | 2018-10-04 | Pei Jia Yang | Ranking system for immunogenic cancer-specific epitopes |
WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
WO2019006401A2 (en) * | 2017-06-30 | 2019-01-03 | Advaxis, Inc. | LISTERIA-BASED IMMUNOGENIC COMPOSITIONS COMPRISING HETERICCLIENT WILMS TUMOR PROTEIN ANTIGENS AND METHODS OF USE THEREOF |
WO2019055618A1 (en) | 2017-09-15 | 2019-03-21 | Arizona Board Of Regents On Behalf Of Arizona State University | METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY |
JP7495137B2 (ja) * | 2018-08-10 | 2024-06-04 | ユーティレックス カンパニー リミテッド | 癌抗原特異的細胞傷害性t細胞 |
TWI856047B (zh) * | 2018-12-19 | 2024-09-21 | 美商信號生物製藥公司 | 多聚體t細胞調節多肽及其使用方法 |
WO2020210632A1 (en) * | 2019-04-10 | 2020-10-15 | Slsg Limited Llc | Multi-valent immunotherapy composition and methods of use for treating wt1-positive cancers |
WO2021067550A1 (en) | 2019-10-02 | 2021-04-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and compositions for identifying neoantigens for use in treating and preventing cancer |
MX2022007905A (es) | 2019-12-31 | 2022-08-25 | Elixirgen Therapeutics Inc | Administracion transitoria basada en temperatura de acidos nucleicos y proteinas a celulas y tejidos. |
EP4087389A4 (en) * | 2020-01-09 | 2024-02-21 | Arizona Board of Regents on behalf of Arizona State University | Antibodies and method of producing antibodies |
US20240216507A1 (en) * | 2020-03-27 | 2024-07-04 | Children's National Medical Center | Sars-cov-2-specific t cells and methods of treatment using them |
CN111647066B (zh) * | 2020-07-01 | 2020-12-18 | 维肽瀛(上海)生物技术有限公司 | Wt1多肽肿瘤抑制剂 |
WO2022056014A1 (en) | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
CN113730562B (zh) * | 2021-09-10 | 2024-06-04 | 中国人民解放军陆军军医大学 | 以壳聚糖修饰plga的wt1多肽纳米粒疫苗及其制备方法和应用 |
Family Cites Families (115)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2016100A (en) | 1932-01-06 | 1935-10-01 | Schwarzkopf Erich | Thermo-magnetically actuated source of power |
US2015101A (en) | 1933-08-16 | 1935-09-24 | Edna W Dieckmann | Terminal fixture aperture indicator |
US2016103A (en) | 1933-09-01 | 1935-10-01 | Hugo J Chott | Dental aligning and testing device |
US2016101A (en) | 1934-03-26 | 1935-10-01 | Charles A Towne | Apparatus for drawing tabs from addressograph plate carriers |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US5837249A (en) | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
US5726288A (en) | 1989-11-13 | 1998-03-10 | Massachusetts Institute Of Technology | Localization and characterization of the Wilms' tumor gene |
US5229115A (en) | 1990-07-26 | 1993-07-20 | Immunex Corporation | Adoptive immunotherapy with interleukin-7 |
EP0573608A1 (en) | 1991-02-07 | 1993-12-15 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
CA2158281A1 (en) | 1993-03-15 | 1994-09-29 | Jay A. Berzofsky | Peptide coated dendritic cells as immunogens |
AU2392795A (en) | 1994-04-22 | 1995-11-16 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Isolation and characterization of a novel primate t-cell lymphotropic virus and the use of this virus or components thereof in diagnostics assays and vaccines |
US5622835A (en) | 1994-04-28 | 1997-04-22 | The Wistar Institute Of Anatomy & Biology | WT1 monoclonal antibodies |
US5643786A (en) | 1995-01-27 | 1997-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for isolating dendritic cells |
US6156316A (en) | 1995-05-08 | 2000-12-05 | Sloan-Kettering Institute For Cancer Research | Oncogene fusion protein peptide vaccines |
JPH11171896A (ja) | 1995-09-19 | 1999-06-29 | Kirin Brewery Co Ltd | 新規ペプチド化合物およびその医薬組成物 |
US5981217A (en) | 1995-12-11 | 1999-11-09 | Mayo Foundation For Medical Education And Research | DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts |
ATE244300T1 (de) | 1996-01-17 | 2003-07-15 | Imp College Innovations Ltd | Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl) |
US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
US6207375B1 (en) | 1996-12-11 | 2001-03-27 | Mayo Foundation For Medical Educational & Research | TGF-β inducible early factor-1 (TIEF-1) and a method to detect breast cancer |
ID27813A (id) | 1998-01-28 | 2001-04-26 | Corixa Corp | Senyawa-senyawa untuk terapi dan diagnosa kanker paru-paru dan metoda untuk penggunaannya |
CN100560130C (zh) | 1998-07-31 | 2009-11-18 | 株式会社国际癌症免疫研究所 | 基于癌抑制基因wt1的产物的癌抗原 |
US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030072767A1 (en) | 1998-09-30 | 2003-04-17 | Alexander Gaiger | Compositions and methods for WT1 specific immunotherapy |
US7063854B1 (en) | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20120301492A1 (en) * | 1998-09-30 | 2012-11-29 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
CA2354369A1 (en) | 1998-12-22 | 2000-06-29 | Genset S.A. | Complementary dna's encoding proteins with signal peptides |
AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
AU3755800A (en) | 1999-03-15 | 2000-10-04 | Introgen Therapeutics, Inc. | Dendritic cells transduced with a wild-type self gene elicit potent antitumor immune responses |
US6593299B1 (en) | 1999-04-21 | 2003-07-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for controlling pests |
AU7859900A (en) | 1999-10-04 | 2001-05-10 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
US20030082194A1 (en) | 2000-02-22 | 2003-05-01 | Alexander Gaiger | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
EP1261711A2 (en) | 2000-02-22 | 2002-12-04 | Corixa Corporation | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
US20040002068A1 (en) | 2000-03-01 | 2004-01-01 | Corixa Corporation | Compositions and methods for the detection, diagnosis and therapy of hematological malignancies |
US6861234B1 (en) | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
EP1209226A3 (en) | 2000-11-07 | 2002-06-05 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Maturation of dendritic cells by recombinant heat shock protein 70 (hsp70) |
US20040097703A1 (en) | 2001-03-22 | 2004-05-20 | Haruo Sugiyama | Wt1 modified peptide |
US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
CA2451846A1 (en) | 2001-06-29 | 2003-01-09 | Chugai Seiyaku Kabushiki Kaisha | Cancer vaccine comprizing a cancer antigen based on the product of a tumor suppressor gene wt1 and a cationic liposome |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
EP1447091A4 (en) | 2001-09-28 | 2008-02-13 | Institute Of Can International | NEW METHOD FOR INDUCTION OF ANTIGEN SPECIFIC T CELLS |
EP1447092A4 (en) | 2001-09-28 | 2007-07-11 | Haruo Sugiyama | METHODS OF INDUCING ANTIGEN-SPECIFIC T CELLS |
US20030072761A1 (en) | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
US20030175272A1 (en) | 2002-03-07 | 2003-09-18 | Medcell Biologics, Inc. | Re-activated T-cells for adoptive immunotherapy |
WO2003106682A1 (ja) | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Hla−a24拘束性癌抗原ペプチド |
KR101173871B1 (ko) | 2003-02-06 | 2012-08-16 | 앤저 테라퓨틱스 인코퍼레이티드 | 변형된 독립생존 미생물, 백신 조성물 및 그것의 사용방법 |
US20050008618A1 (en) | 2003-02-27 | 2005-01-13 | Howard Kaufman | Composition for delivering an agent to a target cell and uses thereof |
US7597894B2 (en) | 2003-03-05 | 2009-10-06 | Dendreon Corporation | Compositions and methods employing alternative reading frame polypeptides for the treatment of cancer and infectious disease |
US10500257B2 (en) | 2003-06-27 | 2019-12-10 | International Institute Of Cancer Immunology, Inc. | Method of selecting WT1 vaccine adaptive patient |
US20050147621A1 (en) | 2003-10-10 | 2005-07-07 | Higgins Darren E. | Use of bacterial 5' untranslated regions for nucleic acid expression |
KR20130062368A (ko) * | 2003-11-05 | 2013-06-12 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | Wt1 유래의 hla-dr 결합성 항원 펩티드 |
CA2548135C (en) | 2003-12-01 | 2014-04-22 | Sloan-Kettering Institute For Cancer Research | Synthetic hla binding peptide analogues and uses thereof |
WO2005054295A2 (en) | 2003-12-05 | 2005-06-16 | Multimmune Gmbh | Therapeutic and diagnostic anti-hsp 70 antibodies |
EP1550458A1 (en) | 2003-12-23 | 2005-07-06 | Vectron Therapeutics AG | Synergistic liposomal adjuvants |
EP1720565A1 (en) | 2004-03-04 | 2006-11-15 | Corixa Corporation | Co-encapsulated wt1 polypeptide and immunostimulant microsphere formulations and methods thereof |
US20050214268A1 (en) | 2004-03-25 | 2005-09-29 | Cavanagh William A Iii | Methods for treating tumors and cancerous tissues |
US20050221481A1 (en) | 2004-03-30 | 2005-10-06 | Istituto Superiore Di Sanita' | Amplification of T cells from human cord blood in serum-deprived culture stimulated with stem cell factor, interleukin-7 and interleukin-2 |
US7622119B2 (en) | 2004-03-31 | 2009-11-24 | International Institute Of Cancer Immunology, Inc. | Cancer antigen peptides derived from WT1 |
US9629927B2 (en) | 2005-07-29 | 2017-04-25 | Sloan-Kettering Institute For Cancer Research | Single wall nanotube constructs and uses thereof |
EP1951281B1 (en) | 2005-10-17 | 2015-04-15 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
DE602006017880D1 (lt) * | 2005-11-30 | 2010-12-09 | Chugai Pharmaceutical Co Ltd | |
CN101384716B (zh) | 2006-02-22 | 2013-03-13 | 株式会社癌免疫研究所 | Hla-a*3303限制性wt1肽和包含此肽的药物组合物 |
WO2007119564A1 (ja) | 2006-03-29 | 2007-10-25 | International Institute Of Cancer Immunology, Inc. | WT1 17AA(-)アイソフォーム特異的siRNAおよびその利用 |
EP3117836A1 (en) | 2006-04-10 | 2017-01-18 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and uses thereof |
WO2007120603A2 (en) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Immunogenic bcr-abl peptides and methods of use thereof |
EP2079760B1 (en) | 2006-12-27 | 2016-04-27 | Emory University | Compositions and methods for the treatment of infections |
CA2670658A1 (en) | 2006-12-28 | 2008-07-10 | International Institute Of Cancer Immunology, Inc. | Hla-a*1101-restricted wt1 peptide and pharmaceutical composition comprising the same |
CN101646455A (zh) | 2007-02-07 | 2010-02-10 | 财团法人阪大微生物病研究会 | 用于癌症的治疗剂 |
CN103103246B (zh) | 2007-02-27 | 2018-05-01 | 株式会社癌免疫研究所 | 活化辅助t细胞的方法以及用于该方法的组合物 |
US20090035360A1 (en) | 2007-05-24 | 2009-02-05 | Dominique Ingrid Lemoine | Lyophilised antigen composition |
KR100995340B1 (ko) | 2007-11-19 | 2010-11-19 | 재단법인서울대학교산학협력재단 | 자연 살해 t 세포의 리간드와 항원을 적재한 단핵구 또는미분화 골수성 세포를 포함하는 백신 |
CA2706907C (en) | 2007-12-05 | 2016-10-18 | International Institute Of Cancer Immunology, Inc. | Cancer vaccine composition |
KR100900837B1 (ko) | 2007-12-07 | 2009-06-04 | (주)두비엘 | 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물 |
KR20110027695A (ko) | 2008-05-19 | 2011-03-16 | 아두로 바이오테크 | Prfa* 돌연변이 리스테리아를 포함하는 조성물 및 그것의 사용방법 |
EP2337795A2 (en) | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
AR076349A1 (es) | 2009-04-23 | 2011-06-01 | Int Inst Cancer Immunology Inc | Peptido auxiliar del antigeno del cancer |
WO2011059835A2 (en) | 2009-11-11 | 2011-05-19 | Quest Diagnostics Investments Incorporated | Wt1 mutations for prognosis of myeloproliferative disorders |
US20110136141A1 (en) | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
WO2011100754A1 (en) | 2010-02-15 | 2011-08-18 | The Trustees Of The University Of Pennsylvania | Live listeria-based vaccines for central nervous system therapy |
US10654892B2 (en) | 2010-10-05 | 2020-05-19 | International Institute Of Cancer Immunology, Inc. | Method for activating helper T cell |
AU2012229266A1 (en) | 2011-03-11 | 2013-05-02 | Gilead Calistoga Llc | Combination therapies for hematologic malignancies |
CN107238706A (zh) | 2011-06-28 | 2017-10-10 | 株式会社癌免疫研究所 | 肽癌抗原‑特异性t细胞的受体基因 |
AU2012291101B2 (en) | 2011-07-29 | 2016-04-07 | Riken | Cell for use in immunotherapy which contains modified nucleic acid construct encoding Wilms tumor gene product or fragment thereof, method for producing said cell, and said nucleic acid construct |
US9539299B2 (en) | 2011-10-27 | 2017-01-10 | International Institute Of Cancer Immunology, Inc. | Combination therapy with WT1 peptide vaccine and temozolomide |
WO2013089252A1 (ja) | 2011-12-14 | 2013-06-20 | 国立大学法人 高知大学 | ヘルパーt細胞誘導性ポリペプチドの改変 |
US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
CN104395462B (zh) | 2012-05-03 | 2017-09-26 | 弗雷德哈钦森癌症研究中心 | 增强亲和力的t细胞受体及其制备方法 |
CN109106945B (zh) | 2012-10-23 | 2023-04-18 | 优比维克有限责任公司 | 用于治疗疾病的同种异体自噬体富集组合物 |
US9833493B2 (en) | 2012-12-17 | 2017-12-05 | International Institute Of Cancer Immunology, Inc. | Method for activating helper T cell |
WO2014103310A1 (ja) | 2012-12-26 | 2014-07-03 | バイオコモ株式会社 | ヒトパラインフルエンザ2型ウイルスベクターを利用したワクチン |
LT2945647T (lt) | 2013-01-15 | 2021-02-25 | Memorial Sloan Kettering Cancer Center | Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai |
RU2685933C2 (ru) | 2013-02-05 | 2019-04-23 | Нитто Денко Корпорейшн | Композиция противораковой вакцины, содержащая пептид wt1, для трансдермального введения |
US10206985B2 (en) | 2013-02-05 | 2019-02-19 | Nitto Denko Corporation | WT1 peptide cancer vaccine composition for mucosal administration |
US10449144B2 (en) | 2013-02-05 | 2019-10-22 | Nitto Denko Corporation | WT1 peptide cancer vaccine composition for transdermal administration |
CN103961305B (zh) | 2013-02-05 | 2019-10-18 | 日东电工株式会社 | 经皮给予用wt1肽癌症疫苗带状制剂 |
ES2662333T3 (es) | 2013-02-14 | 2018-04-06 | Immunocellular Therapeutics Ltd. | Vacunas contra el cáncer y métodos de vacunación |
CN105142656B (zh) | 2013-03-12 | 2019-05-10 | 大日本住友制药株式会社 | 水性液体组合物 |
WO2014144885A2 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of The University Of Pennsylvania | Cancer vaccines and methods of treatment using the same |
SG11201507883SA (en) | 2013-03-29 | 2015-10-29 | Sumitomo Dainippon Pharma Co Ltd | Wt1-antigen peptide conjugate vaccine |
EP2988762B1 (en) | 2013-04-25 | 2018-06-06 | Vaximm AG | Salmonella-based vectors for cancer immunotherapy targeting wilms' tumor gene wt1 |
JP6634287B2 (ja) | 2013-05-13 | 2020-01-22 | 株式会社癌免疫研究所 | 免疫療法の臨床効果の予測法 |
US10898555B2 (en) | 2013-07-02 | 2021-01-26 | Japanese Foundation For Cancer Research | Cellular immunity inducing vaccine |
EP3071594A4 (en) | 2013-11-22 | 2017-05-03 | The Board of Trustees of the University of Illionis | Engineered high-affinity human t cell receptors |
ES2747772T3 (es) | 2013-12-18 | 2020-03-11 | Vaximm Gmbh | Vacuna de ADN dirigida a MSLN para la inmunoterapia del cáncer |
US10835595B2 (en) | 2014-01-06 | 2020-11-17 | The Trustees Of The University Of Pennsylvania | PD1 and PDL1 antibodies and vaccine combinations and use of same for immunotherapy |
CN106029699B (zh) | 2014-02-26 | 2019-07-19 | 泰来有限公司 | Wt1抗原性多肽和含有该多肽的抗肿瘤剂 |
US10023841B2 (en) | 2014-05-23 | 2018-07-17 | Baylor Research Institute | Methods and compositions for treating breast cancer with dendritic cell vaccines |
MX2017007595A (es) | 2014-12-11 | 2018-03-01 | Int Inst Cancer Immunology Inc | Inmunoterapia para enfermedad angiogenica. |
JP6770269B2 (ja) | 2015-06-25 | 2020-10-14 | 国立大学法人神戸大学 | 経口腫瘍ワクチン |
WO2017049074A1 (en) | 2015-09-18 | 2017-03-23 | Moderna Therapeutics, Inc. | Polynucleotide formulations for use in the treatment of renal diseases |
-
2014
- 2014-01-15 LT LTEP14741142.5T patent/LT2945647T/lt unknown
- 2014-01-15 CN CN202310197249.5A patent/CN116789792A/zh active Pending
- 2014-01-15 EP EP20193303.3A patent/EP3769782A1/en active Pending
- 2014-01-15 SI SI201431713T patent/SI2945647T1/sl unknown
- 2014-01-15 SM SM20200677T patent/SMT202000677T1/it unknown
- 2014-01-15 US US14/760,997 patent/US9919037B2/en active Active
- 2014-01-15 CN CN202310197251.2A patent/CN116253788A/zh active Pending
- 2014-01-15 WO PCT/US2014/011711 patent/WO2014113490A2/en active Application Filing
- 2014-01-15 PT PT147411425T patent/PT2945647T/pt unknown
- 2014-01-15 EP EP14741142.5A patent/EP2945647B1/en active Active
- 2014-01-15 CA CA2898099A patent/CA2898099A1/en active Pending
- 2014-01-15 PL PL14741142T patent/PL2945647T3/pl unknown
- 2014-01-15 HU HUE14741142A patent/HUE052541T2/hu unknown
- 2014-01-15 ES ES14741142T patent/ES2832546T3/es active Active
- 2014-01-15 AU AU2014207615A patent/AU2014207615B2/en active Active
- 2014-01-15 CN CN201480010289.3A patent/CN105377291B/zh active Active
- 2014-01-15 RS RS20201426A patent/RS61173B1/sr unknown
- 2014-01-15 CN CN201910196887.9A patent/CN110078813B/zh active Active
- 2014-01-15 DK DK14741142.5T patent/DK2945647T3/da active
- 2014-01-15 JP JP2015552683A patent/JP6486278B2/ja active Active
-
2018
- 2018-10-08 AU AU2018241209A patent/AU2018241209B2/en active Active
-
2019
- 2019-02-19 JP JP2019027238A patent/JP6853842B2/ja active Active
-
2020
- 2020-10-09 AU AU2020250313A patent/AU2020250313B2/en active Active
- 2020-11-16 CY CY20201101087T patent/CY1123563T1/el unknown
- 2020-11-25 HR HRP20201867TT patent/HRP20201867T1/hr unknown
- 2020-12-18 JP JP2020209931A patent/JP7097943B2/ja active Active
-
2022
- 2022-06-28 JP JP2022103228A patent/JP7589193B2/ja active Active
-
2023
- 2023-03-14 AU AU2023201564A patent/AU2023201564A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LT2945647T (lt) | Imunogeniniai wt-1 peptidai ir jų panaudojimo būdai | |
NO2023026I1 (no) | Dengue tetravalent vaccine | |
HUE036109T2 (hu) | Roseburia flagellin és immunmodulálás | |
LT3708579T (lt) | Klaudinui-6 specifiniai imunoreceptoriai ir t ląstelių epitopai | |
LT2970303T (lt) | Pakeistieji ksantinai ir jų panaudojimo metodai | |
DK3043784T3 (da) | Arylethere og anvendelser deraf | |
DK2941163T3 (da) | Hudrenser | |
LT3021852T (lt) | Neuroaktyvūs steroidai, jų kompozicijos ir panaudojimas | |
DK2968443T3 (da) | Hepcidinanaloger og anvendelser deraf | |
LT3363438T (lt) | Pakeistieji 2-azabiciklai ir jų panaudojimas kaip oreksino receptorių moduliatorių | |
LT3003039T (lt) | Metil/fluor-piridinil-metoksi grupės pakeistieji piridinono-piridinilo junginiai ir fluor-pirimidinil-metoksi grupės pakeistieji piridinono-piridinilo junginiai | |
LT3311845T (lt) | Terapinės polimerinės nanodalelės ir jų gamybos bei panaudojimo būdai | |
DK2962100T3 (da) | Tuberkulosebiomarkører og anvendelser deraf | |
LT2989088T (lt) | Dolastatino 10 ir auristatinų dariniai | |
EP2958994A4 (en) | Vaccine composition | |
HK1214838A1 (zh) | 肽及包含它們的疫苗 | |
DK2969005T3 (da) | Attenuerede influenzavira og -vacciner | |
LT3030259T (lt) | Peptidai | |
LT3060660T (lt) | Rekombinantiniai glikoproteinai ir jų naudojimas | |
DK2958935T3 (da) | Vaccine | |
DK2976101T3 (da) | Behandlingsfremgangsmåde | |
DK3079716T3 (da) | Multiepitop-tarp-peptidvaccine og anvendelser deraf. | |
DK3041506T3 (da) | Behandlingsfremgangsmåde | |
FI20136034A (fi) | Sauna | |
CL2014000649S1 (es) | Sombrilla |