KR970704729A - 타키키닌 길항물질로서의 락탐(azetidin-1-ylalkyl lactams as tachykinen antagonists) - Google Patents
타키키닌 길항물질로서의 락탐(azetidin-1-ylalkyl lactams as tachykinen antagonists)Info
- Publication number
- KR970704729A KR970704729A KR1019970700816A KR19970700816A KR970704729A KR 970704729 A KR970704729 A KR 970704729A KR 1019970700816 A KR1019970700816 A KR 1019970700816A KR 19970700816 A KR19970700816 A KR 19970700816A KR 970704729 A KR970704729 A KR 970704729A
- Authority
- KR
- South Korea
- Prior art keywords
- tachykinen
- ylalkyl
- azetidin
- lactams
- lactam
- Prior art date
Links
- 150000003951 lactams Chemical class 0.000 title 2
- 239000005557 antagonist Substances 0.000 title 1
- 239000002462 tachykinin receptor antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9416084A GB9416084D0 (en) | 1994-08-09 | 1994-08-09 | Lactams |
GB9416084.3 | 1994-08-09 | ||
GB9417898.5 | 1994-09-06 | ||
GB9417898A GB9417898D0 (en) | 1994-08-09 | 1994-09-06 | Lactams |
PCT/EP1995/003054 WO1996005193A1 (en) | 1994-08-09 | 1995-07-29 | (azetidin-1-ylalkyl)lactams as tachykinin antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
KR970704729A true KR970704729A (ko) | 1997-09-06 |
KR100218626B1 KR100218626B1 (ko) | 1999-09-01 |
Family
ID=10759627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970700816A KR100218626B1 (ko) | 1994-08-09 | 1995-07-29 | 타키키닌 길항물질로서의 (아제티딘-1-일알킬)락탐 |
Country Status (5)
Country | Link |
---|---|
KR (1) | KR100218626B1 (ko) |
CO (1) | CO4410338A1 (ko) |
GB (2) | GB9416084D0 (ko) |
PE (1) | PE34696A1 (ko) |
PL (1) | PL183180B1 (ko) |
-
1994
- 1994-08-09 GB GB9416084A patent/GB9416084D0/en active Pending
- 1994-09-06 GB GB9417898A patent/GB9417898D0/en active Pending
-
1995
- 1995-07-29 KR KR1019970700816A patent/KR100218626B1/ko not_active IP Right Cessation
- 1995-07-29 PL PL95318534A patent/PL183180B1/pl unknown
- 1995-08-03 PE PE1995275289A patent/PE34696A1/es not_active Application Discontinuation
- 1995-08-08 CO CO95035201A patent/CO4410338A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR100218626B1 (ko) | 1999-09-01 |
GB9417898D0 (en) | 1994-10-26 |
GB9416084D0 (en) | 1994-09-28 |
PL318534A1 (en) | 1997-06-23 |
PL183180B1 (pl) | 2002-05-31 |
CO4410338A1 (es) | 1997-01-09 |
PE34696A1 (es) | 1996-10-01 |
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Legal Events
Date | Code | Title | Description |
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PA0105 | International application |
Patent event date: 19970206 Patent event code: PA01051R01D Comment text: International Patent Application |
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PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19970326 Comment text: Request for Examination of Application |
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PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19981226 Patent event code: PE09021S01D |
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E701 | Decision to grant or registration of patent right | ||
PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19990429 |
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GRNT | Written decision to grant | ||
PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19990610 Patent event code: PR07011E01D |
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PR1002 | Payment of registration fee |
Payment date: 19990611 End annual number: 3 Start annual number: 1 |
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PG1601 | Publication of registration | ||
FPAY | Annual fee payment |
Payment date: 20020520 Year of fee payment: 4 |
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PR1001 | Payment of annual fee |
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