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KR970027055A - Method for preparing 1-substituted pyrrole-3-carboxylic acid derivative - Google Patents

Method for preparing 1-substituted pyrrole-3-carboxylic acid derivative Download PDF

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Publication number
KR970027055A
KR970027055A KR1019960051511A KR19960051511A KR970027055A KR 970027055 A KR970027055 A KR 970027055A KR 1019960051511 A KR1019960051511 A KR 1019960051511A KR 19960051511 A KR19960051511 A KR 19960051511A KR 970027055 A KR970027055 A KR 970027055A
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KR
South Korea
Prior art keywords
formula
preparing
carboxylic acid
substituted pyrrole
acid derivative
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Application number
KR1019960051511A
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Korean (ko)
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KR100460414B1 (en
Inventor
마사히로 이모토
아키라 미즈노
마코토 시바타
토모에 이와모리
Original Assignee
도리이 신이치로
산토리 가부시키가이샤
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Application filed by 도리이 신이치로, 산토리 가부시키가이샤 filed Critical 도리이 신이치로
Publication of KR970027055A publication Critical patent/KR970027055A/en
Application granted granted Critical
Publication of KR100460414B1 publication Critical patent/KR100460414B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

본 발명은 화학식(Ⅰ)의 1-치환 피롤-3-카르복시산 유도체의 간단하고 산업적으로 유용한 제조방법을 제공한다. 상기 방법은 화학식(Ⅱ)의 화합물과 화학식(Ⅲ)의 화합물 및 산 무수물을 하기의 반응식에 따라 반응시키는 것을 포함한다 :The present invention provides a simple and industrially useful process for preparing the 1-substituted pyrrole-3-carboxylic acid derivatives of formula (I). The method comprises reacting a compound of formula (II) with a compound of formula (III) and an acid anhydride according to the following scheme:

상기 식에서, R1및 R2는 독립적으로 알킬, 아르알킬, 또는 아릴기를 나타낸다.In the above formula, R 1 and R 2 independently represent an alkyl, aralkyl, or aryl group.

Description

1-치환 피롤-3-카르복시산 유도체의 제조방법Method for preparing 1-substituted pyrrole-3-carboxylic acid derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

하기 화학식(Ⅱ)의 화합물과 하기 화학식(Ⅲ)의 화합물 및 산 무수물을 반응시키는 것을 포함하는, 하기 화학식(Ⅰ)의 1-치환 피롤-3-카르복시산 유도체의 제조방법 :A process for preparing a 1-substituted pyrrole-3-carboxylic acid derivative of formula (I) comprising reacting a compound of formula (II) with a compound of formula (III) and an acid anhydride: 상기 식에서, R1및 R2는 독립적으로 알킬, 아르알킬, 또는 아릴기를 나타낸다.In the above formula, R 1 and R 2 independently represent an alkyl, aralkyl, or aryl group. 제1항에 있어서, 산 무수물이 아세트산 무수물인 것을 특징으로 하는 방법.The method of claim 1 wherein the acid anhydride is acetic anhydride. 제1항에 있어서, 반응이 아세트산 무수물중에서 수행되는 것을 특징으로 하는 방법.The process according to claim 1, wherein the reaction is carried out in acetic anhydride. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019960051511A 1995-11-02 1996-11-01 Process for preparing 1-substituted pyrrole-3-carbozylic acie deriavatives KR100460414B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP308540/1995 1995-11-02
JP30854095 1995-11-02
JP1995-308540 1995-11-02

Publications (2)

Publication Number Publication Date
KR970027055A true KR970027055A (en) 1997-06-24
KR100460414B1 KR100460414B1 (en) 2005-01-26

Family

ID=49382125

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960051511A KR100460414B1 (en) 1995-11-02 1996-11-01 Process for preparing 1-substituted pyrrole-3-carbozylic acie deriavatives

Country Status (1)

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KR (1) KR100460414B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560700A (en) * 1985-02-08 1985-12-24 Merrell Dow Pharmaceuticals Inc. Pyrrole-3-carboxylate cardiotonic agents
JPH06104658B2 (en) * 1988-06-23 1994-12-21 三菱化成株式会社 Pyrrolecarboxylic acid derivative

Also Published As

Publication number Publication date
KR100460414B1 (en) 2005-01-26

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