KR960003724A - 간질환 치료용 약제조성물 - Google Patents
간질환 치료용 약제조성물 Download PDFInfo
- Publication number
- KR960003724A KR960003724A KR1019940017855A KR19940017855A KR960003724A KR 960003724 A KR960003724 A KR 960003724A KR 1019940017855 A KR1019940017855 A KR 1019940017855A KR 19940017855 A KR19940017855 A KR 19940017855A KR 960003724 A KR960003724 A KR 960003724A
- Authority
- KR
- South Korea
- Prior art keywords
- pharmaceutical composition
- formula
- compound
- weight
- parts
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 7
- 208000019423 liver disease Diseases 0.000 title abstract 2
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 claims abstract 4
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 claims abstract 4
- 229960001661 ursodiol Drugs 0.000 claims abstract 4
- BKRIRZXWWALTPU-UHFFFAOYSA-N methyl 4-(4-methoxycarbonylphenyl)benzoate Chemical compound C1=CC(C(=O)OC)=CC=C1C1=CC=C(C(=O)OC)C=C1 BKRIRZXWWALTPU-UHFFFAOYSA-N 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940093429 polyethylene glycol 6000 Drugs 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (5)
- 다음 구조식(1)로 표시되는 비페닐디메칠 디카복시레이트(DDB)와 다음 구조식(2)로 표시되는 우르소데옥시콜린산(UDCA) 및 약제학적으로 허용되는 부형제로 이루어진 것을 특징으로 하는 약제조성물.
- 제1항에 있어서, 상기 구조식(1) 화합물은 폴리소르베이트 80과 폴리에칠렌글리콜 6000를 사용하여 통상의 용융-용매법으로 처리한 것임을 특징으로 하는 약제조성물.
- 제1항에 있어서, 상기 구조식(1) 화합물과 구조식(2) 화합물의 유효량은 각각 7∼30 중량부와 30∼100중량부로 혼합된 것임을 특징으로 하는 약제조성물.
- 제1항에 있어서, 상기 구조식(1) 화합물의 유효량이 25중량부이고, 구조식(2) 화합물의 유효량이 50중량부임을 특징으로 하는 약제조성물.
- 제1항에 있어서, 상기 구조식(2) 화합물의 유효량이 12.5 중량부이고, 구조식(2) 화합물의 유효량이 50중량임을 특징으로 하는 약제 조성물.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019940017855A KR0142809B1 (ko) | 1994-07-23 | 1994-07-23 | 간질환 치료용 약제조성물 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019940017855A KR0142809B1 (ko) | 1994-07-23 | 1994-07-23 | 간질환 치료용 약제조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR960003724A true KR960003724A (ko) | 1996-02-23 |
KR0142809B1 KR0142809B1 (ko) | 1998-07-15 |
Family
ID=19388643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940017855A KR0142809B1 (ko) | 1994-07-23 | 1994-07-23 | 간질환 치료용 약제조성물 |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR0142809B1 (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100626414B1 (ko) * | 2003-08-27 | 2006-09-20 | 선종건 | 간염 치료용 약제조성물 |
-
1994
- 1994-07-23 KR KR1019940017855A patent/KR0142809B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR0142809B1 (ko) | 1998-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR950014073A (ko) | 이소퀴놀린 | |
ES8705393A1 (es) | Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85) | |
ATE219363T1 (de) | Lösliche prodrugs von paclitaxel | |
IT1252868B (it) | Composizione farmaceutica anticefalalgica per somministrazione endonasale, procedimento per prepararla e suo impiego terapeutico | |
RU95113862A (ru) | Производные пирролопиримидинов, фармацевтическая композиция, промежуточные соединения | |
KR890011837A (ko) | 디데하이드로 비타민 d₃유도체 | |
BR9401183A (pt) | Composto e formulação farmacêutica | |
KR940002210A (ko) | 24-시클로프로판 비타민 d 유도체 | |
BR9814498A (pt) | Processo para o tratamento de obesidade em um humano necessitando de tal tratamento, composto, uso do mesmo, produto, e, composição farmacêutica | |
EA199800013A1 (ru) | Способы минимизации остеопороза | |
MX9303139A (es) | Procedimiento para la preparacion de derivados esteroides 11-ceto. | |
RU2218334C2 (ru) | Замещенные 1,2,3,4,5,6-гексагидро-2,6-метано-3-бензазоцин-10-олы и фармацевтическая композиция на их основе | |
ATE107167T1 (de) | Pharmazeutische zubereitungen für neuroschutz, die arylcyclohexylamine enthalten. | |
KR900009606A (ko) | 불소-함유 2-니트로 이미다졸 유도체 및 그를 함유하는 방사선 증감제 | |
KR950703941A (ko) | 일산화질소 합성 억제제(nitrogen monoxide synthesis inhibitor) | |
ATE17727T1 (de) | Alkylenverbrueckte guanidinothiazolderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel. | |
KR960003724A (ko) | 간질환 치료용 약제조성물 | |
FI834800A0 (fi) | Foerfarande foer framstaellning av dialkylaminoalkoxibensylalkohol-derivat | |
KR970705999A (ko) | 타목시펜 및 타목시펜 유사체의 자궁향성 효과를 최소화시키는 방법 (a method for minimizing the uterotrophic effect of tamoxifen and tamoxifen analogs) | |
CA2231025A1 (fr) | Nouveaux composes de 2-amino indane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
DE69116404T2 (de) | Tenidap als Hemmstoff der Elastinfreisetzung durch Neutrophile | |
ES2084348T3 (es) | N-((4,5-dihidroxi- y 4,5,8-trihidroxi-9,10-dihidro-9,10-dioxo-2-antracen-il)carbonil)aminoacidos utiles en la terapia de afecciones osteoarticulares. | |
ATE160938T1 (de) | Feste orale pharmazeutische zubereitung mit gemfibrozil als aktiver inhaltsstoff und verfahren zur herstellung | |
KR910019974A (ko) | 치환된 인돌 | |
JP3200723B2 (ja) | 育毛剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19940723 |
|
PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19940723 Comment text: Request for Examination of Application |
|
PG1501 | Laying open of application | ||
E902 | Notification of reason for refusal | ||
PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19970908 Patent event code: PE09021S01D |
|
E701 | Decision to grant or registration of patent right | ||
PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19980105 |
|
GRNT | Written decision to grant | ||
PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19980403 Patent event code: PR07011E01D |
|
PR1002 | Payment of registration fee |
Payment date: 19980403 End annual number: 3 Start annual number: 1 |
|
PG1601 | Publication of registration | ||
PR1001 | Payment of annual fee |
Payment date: 20010404 Start annual number: 4 End annual number: 4 |
|
PR1001 | Payment of annual fee |
Payment date: 20020403 Start annual number: 5 End annual number: 5 |
|
PR1001 | Payment of annual fee |
Payment date: 20030325 Start annual number: 6 End annual number: 6 |
|
PR1001 | Payment of annual fee |
Payment date: 20040324 Start annual number: 7 End annual number: 7 |
|
J204 | Request for invalidation trial [patent] | ||
PJ0204 | Invalidation trial for patent |
Patent event date: 20040826 Comment text: Request for Trial Patent event code: PJ02042R01D Patent event date: 19980403 Comment text: Registration of Establishment Patent event code: PJ02041E01I Appeal kind category: Invalidation Request date: 20040826 Decision date: 20041021 Appeal identifier: 2004100001847 |
|
J121 | Written withdrawal of request for trial | ||
PJ1201 | Withdrawal of trial |
Patent event code: PJ12011R01D Patent event date: 20041021 Comment text: Written Withdrawal of Request for Trial Appeal identifier: 2004100001847 Request date: 20040826 Appeal kind category: Invalidation Decision date: 20041021 |
|
PR1001 | Payment of annual fee |
Payment date: 20050308 Start annual number: 8 End annual number: 8 |
|
PR1001 | Payment of annual fee |
Payment date: 20060404 Start annual number: 9 End annual number: 9 |
|
PR1001 | Payment of annual fee |
Payment date: 20070404 Start annual number: 10 End annual number: 10 |
|
PR1001 | Payment of annual fee |
Payment date: 20080404 Start annual number: 11 End annual number: 11 |
|
PR1001 | Payment of annual fee |
Payment date: 20090406 Start annual number: 12 End annual number: 12 |
|
PR1001 | Payment of annual fee |
Payment date: 20100423 Start annual number: 13 End annual number: 13 |
|
PR1001 | Payment of annual fee |
Payment date: 20110330 Start annual number: 14 End annual number: 14 |
|
PR1001 | Payment of annual fee |
Payment date: 20120403 Start annual number: 15 End annual number: 15 |
|
FPAY | Annual fee payment |
Payment date: 20130403 Year of fee payment: 16 |
|
PR1001 | Payment of annual fee |
Payment date: 20130403 Start annual number: 16 End annual number: 16 |
|
FPAY | Annual fee payment |
Payment date: 20140521 Year of fee payment: 17 |
|
PR1001 | Payment of annual fee |
Payment date: 20140521 Start annual number: 17 End annual number: 17 |
|
EXPY | Expiration of term | ||
PC1801 | Expiration of term |
Termination date: 20150123 Termination category: Expiration of duration |