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KR960003722A - 장용성 듀로세틴 펠릿 - Google Patents

장용성 듀로세틴 펠릿 Download PDF

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Publication number
KR960003722A
KR960003722A KR1019950020885A KR19950020885A KR960003722A KR 960003722 A KR960003722 A KR 960003722A KR 1019950020885 A KR1019950020885 A KR 1019950020885A KR 19950020885 A KR19950020885 A KR 19950020885A KR 960003722 A KR960003722 A KR 960003722A
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KR
South Korea
Prior art keywords
enteric
pellets
durocetin
durosetin
layer
Prior art date
Application number
KR1019950020885A
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English (en)
Other versions
KR100356240B1 (ko
Inventor
로버트 앤더슨 네일
로이드 오렌 피터
오구라 도시히로
후지 도시로
Original Assignee
피터 지. 스트링거
일라이 릴리 앤드 캄파니
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23055767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR960003722(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 피터 지. 스트링거, 일라이 릴리 앤드 캄파니 filed Critical 피터 지. 스트링거
Publication of KR960003722A publication Critical patent/KR960003722A/ko
Application granted granted Critical
Publication of KR100356240B1 publication Critical patent/KR100356240B1/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

본 발명은 장용성 층이 하이드록시 프로필메틸셀룰로스 아세테이트 숙신산염을 포함하는 장용성 펠릿의 형태로 되어있는 우울증 치료제인 듀로세틴의 탁월한 장용성 제제에 관한 것이다.

Description

장용성 듀로세틴 펠릿
내용없음

Claims (1)

  1. (a) 듀로세틴 및 약학적으로 허용되는 부형제로 이루어진 핵심부 : (b) 임의의 분리층 : (c) 하이드록시 프로필메틸셀룰로스 아세테이트 숙신산염(HPMCAS) 및 약학적으로 허용되는 부형제를 포함하는 장용성 층; (d) 임의의 마무리층으로 이루어진 장용성 듀로세틴 펠릿.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950020885A 1994-07-18 1995-07-15 장용성듀로세틴펠릿 KR100356240B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8/276,232 1994-07-18
US08/276,232 US5508276A (en) 1994-07-18 1994-07-18 Duloxetine enteric pellets
US08/276,232 1994-07-18

Publications (2)

Publication Number Publication Date
KR960003722A true KR960003722A (ko) 1996-02-23
KR100356240B1 KR100356240B1 (ko) 2002-12-26

Family

ID=23055767

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950020885A KR100356240B1 (ko) 1994-07-18 1995-07-15 장용성듀로세틴펠릿

Country Status (30)

Country Link
US (1) US5508276A (ko)
EP (1) EP0693282B1 (ko)
JP (1) JP3707831B2 (ko)
KR (1) KR100356240B1 (ko)
CN (1) CN1106191C (ko)
AT (1) ATE200620T1 (ko)
AU (1) AU686384B2 (ko)
BR (1) BR9503346A (ko)
CA (1) CA2153856C (ko)
CO (1) CO4410177A1 (ko)
CZ (1) CZ288095B6 (ko)
DE (1) DE69520711T2 (ko)
DK (1) DK0693282T3 (ko)
ES (1) ES2157297T3 (ko)
GE (1) GEP20063944B (ko)
GR (1) GR3036185T3 (ko)
HU (1) HU221502B (ko)
IL (1) IL114584A (ko)
MY (1) MY116361A (ko)
NO (2) NO312397B1 (ko)
NZ (1) NZ272554A (ko)
PE (1) PE32196A1 (ko)
PL (1) PL181296B1 (ko)
PT (1) PT693282E (ko)
RU (1) RU2147231C1 (ko)
SI (1) SI0693282T1 (ko)
TW (1) TW382596B (ko)
UA (1) UA41344C2 (ko)
YU (1) YU49445B (ko)
ZA (1) ZA955799B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8397404B2 (en) 2006-03-07 2013-03-19 Jung Bae Kim Health shoes

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997003665A1 (en) * 1995-07-24 1997-02-06 Eli Lilly And Company Treatment of attention-deficit/hyperactivity disorder
US5910319A (en) * 1997-05-29 1999-06-08 Eli Lilly And Company Fluoxetine enteric pellets and methods for their preparation and use
ATE449603T1 (de) * 1998-09-15 2009-12-15 Lilly Co Eli Verwendung von duloxetine zur behandlung von fibromyalgie
ES2306646T3 (es) * 1999-02-09 2008-11-16 Pfizer Products Inc. Composiciones de farmacos basicos con biodisponibilidad incrementada.
IL130602A0 (en) * 1999-06-22 2000-06-01 Dexcel Ltd Stable benzimidazole formulation
US6683114B2 (en) * 2000-03-07 2004-01-27 Eli Lilly And Company Treatment of psoriasis
WO2002078691A1 (en) * 2001-03-29 2002-10-10 Eli Lilly And Company Duloxetine for treatment of hot flashes
CA2450957A1 (en) 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions of dispersions of drugs and neutral polymers
DE60237602D1 (de) * 2001-06-22 2010-10-21 Bend Res Inc Pharmazeutische zusammensetzung enthaltend schwer lösliche und säureempfindliche arzneistoffe und neutralisierte anionische polymere
CN1713906A (zh) * 2002-11-19 2005-12-28 伊莱利利公司 用度洛西汀进行的对胃肠道疾病的治疗
SI1648421T1 (en) * 2003-07-24 2018-02-28 Glaxosmithkline Llc Films dissolving in the mouth
JP5121229B2 (ja) * 2004-04-08 2013-01-16 協和発酵キリン株式会社 安定性の向上した固形製剤およびその製造方法
GB0410470D0 (en) * 2004-05-11 2004-06-16 Cipla Ltd Pharmaceutical compound and polymorphs thereof
WO2006071868A2 (en) * 2004-12-23 2006-07-06 Teva Pharmaceutical Industries Ltd. Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
EP1856087A1 (en) * 2005-03-08 2007-11-21 Teva Pharmaceutical Industries Limited Crystal forms of (s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine oxalate and the preparation thereof
EP1858874A1 (en) * 2005-03-14 2007-11-28 Teva Pharmaceutical Industries Ltd. (s)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine-di-p-toluoyl-l-tartarate and methods of preparation thereof
WO2007034503A2 (en) * 2005-06-20 2007-03-29 Cadila Healthcare Limited Controlled release dosage formulation of duloxetine
US8153824B2 (en) * 2005-06-22 2012-04-10 The Wockhardt Company Antidepressant oral liquid compositions
DK1915137T3 (da) 2005-08-10 2013-11-04 Add Advanced Drug Delivery Technologies Ltd Oralt præparat med kontrolleret frisætning
US20060165776A1 (en) * 2005-08-31 2006-07-27 Ramesh Sesha Antidepressant oral pharmaceutical compositions
US20080207923A1 (en) * 2005-09-22 2008-08-28 Santiago Ini Pure DNT-maleate and methods of preparation thereof
US7842717B2 (en) * 2005-09-22 2010-11-30 Teva Pharmaceutical Industries Ltd. DNT-maleate and methods of preparation thereof
WO2007062119A1 (en) * 2005-11-23 2007-05-31 Auspex Pharmaceuticals, Inc. Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity
WO2007067581A1 (en) * 2005-12-05 2007-06-14 Teva Pharmaceutical Industries Ltd. 2-(n-methyl-propanamine)-3-(2-naphthol) thiophene, an impurity of duloxetine hydrochloride
DE102005060393A1 (de) * 2005-12-16 2007-06-21 Add Advanced Drug Delivery Technologies Ltd. Orales Präparat mit kontrollierter Freisetzung
US20070191471A1 (en) * 2006-01-23 2007-08-16 Santiago Ini DNT-fumarate and methods of preparation thereof
EP1820800A1 (en) * 2006-02-17 2007-08-22 KRKA, tovarna zdravil, d.d., Novo mesto Crystalline forms of duloxetine hydrochloride and processes for their preparation
CN101448493A (zh) * 2006-05-22 2009-06-03 特瓦制药工业有限公司 度洛西汀盐酸盐延迟释放配制剂
EP1934197A2 (en) * 2006-05-23 2008-06-25 Teva Pharmaceutical Industries Ltd Duloxetine hcl polymorphs
JP5052051B2 (ja) * 2006-06-16 2012-10-17 トーアエイヨー株式会社 腸溶性顆粒剤及びその製造方法
WO2008020286A2 (en) * 2006-08-14 2008-02-21 Torrent Pharmaceuticals Limited Pharmaceutical compositions of duloxetine
CN101190208B (zh) * 2006-11-30 2011-11-02 石药集团中奇制药技术(石家庄)有限公司 一种含有盐酸度洛西汀的药物制剂及其制备方法
WO2008077645A1 (en) 2006-12-22 2008-07-03 Synthon B.V. Process for making duloxetine and related compounds
EP2018860A1 (en) * 2007-07-16 2009-01-28 LEK Pharmaceuticals D.D. Duloxetine composition
WO2008077939A2 (en) * 2006-12-27 2008-07-03 Lek Pharmaceuticals D.D. Duloxetine composition
EP1938840A1 (en) * 2006-12-27 2008-07-02 LEK Pharmaceuticals D.D. Duloxetine composition
US20080226711A1 (en) * 2007-03-12 2008-09-18 Torrent Pharmaceuticals Ltd. Pharmaceutical compositions of duloxetine
US9358213B2 (en) * 2007-04-20 2016-06-07 Wockhardt Limited Pharmaceutical compositions of duloxetine
WO2009004649A2 (en) * 2007-05-21 2009-01-08 Sun Pharmaceutical Industries Limited Enteric coated pharmaceutical compositions
GB0712220D0 (en) * 2007-06-23 2007-08-01 Arrow Int Ltd Duloxetine formulation
WO2009066181A2 (en) * 2007-07-09 2009-05-28 Combino Pharm, S.L. Oral delayed-release duloxentine hydrochloride pellets
EP2182929A2 (en) * 2007-07-13 2010-05-12 Synthon B.V. Duloxetine formulations
WO2009087657A2 (en) * 2007-11-03 2009-07-16 Alkem Laboratories Ltd. Stable pharmaceutical composition of duloxetine and process for its preparation
EP2231169B1 (en) * 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US9233078B2 (en) 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
AU2009206204B2 (en) * 2008-01-25 2015-03-19 Alphapharm Pty Ltd Delayed release pharmaceutical composition of duloxetine
US20090226517A1 (en) * 2008-02-06 2009-09-10 Vinita Umashankar Vyas Pharmaceutical formulations comprising duloxetine
US20110020439A1 (en) * 2008-03-24 2011-01-27 Shrenik Annasaheb Kole Delayed release compositions of duloxetine
EP2293782B1 (en) * 2008-05-06 2015-08-12 Dexcel Pharma Technologies Ltd. Stable benzimidazole formulation
EP2133072A1 (en) 2008-06-13 2009-12-16 KRKA, D.D., Novo Mesto Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives
US20100040680A1 (en) * 2008-08-15 2010-02-18 Felix Lai Multiparticulate selective serotonin and norepinephrine reuptake inhibitor formulation
ES2376095B1 (es) * 2008-10-02 2013-01-24 Laboratorios Del Dr. Esteve, S.A. Pellets entéricos de duloxetina.
CN101756960B (zh) 2008-12-26 2012-06-27 上海中西制药有限公司 一种度洛西汀肠溶制剂及其芯材和制备方法
WO2010078878A1 (en) * 2009-01-12 2010-07-15 Synthon B.V. Duloxetine formulations
US8758779B2 (en) * 2009-06-25 2014-06-24 Wockhardt Ltd. Pharmaceutical composition of duloxetine
DE102009033621A1 (de) 2009-07-17 2011-01-20 Add Technologies Ltd. Trennschichten für pharmazeutische Zubereitungen zur Verhinderung von Wechselwirkungen zwischen Arzneistoffen und pharmazeutisch-technologischen Hilfsstoffen
WO2011039768A2 (en) * 2009-09-17 2011-04-07 Cadila Healthcare Limited Pharmaceutical compositions for reducing alcohol-induced dose dumping
DK2512455T3 (en) * 2009-12-18 2014-03-24 Frieslandcampina Nederland Holding B V Co-treated tablet adjuvant composition, its preparation and use
SG183993A1 (en) * 2010-03-09 2012-10-30 Alkermes Pharma Ireland Ltd Alcohol resistant enteric pharmaceutical compositions
EP2377525A1 (en) 2010-03-26 2011-10-19 Laboratorios del Dr. Esteve S.A. Duloxetine enteric pellets
WO2011148380A1 (en) * 2010-05-25 2011-12-01 Hetero Research Foundation Oral pharmaceutical composition of duloxetine
CN102908331A (zh) * 2011-08-01 2013-02-06 浙江九洲药物科技有限公司 一种盐酸度洛西汀肠溶胶囊及其制备方法
NO2659881T3 (ko) 2012-04-30 2018-04-28
WO2013164121A1 (en) * 2012-05-02 2013-11-07 Capsugel France SAS Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas)
CN103505421B (zh) * 2012-06-29 2018-04-27 石药集团中奇制药技术(石家庄)有限公司 一种盐酸度洛西汀的肠溶微丸制剂
CN103211777A (zh) * 2013-03-31 2013-07-24 北京万全阳光医学技术有限公司 一种盐酸度洛西汀的药物制剂及其制备的方法
GR1008228B (el) * 2013-04-23 2014-06-16 "Φαρματεν Α.Β.Ε.Ε.", Φαρμακευτικο σκευασμα περιεχον ενα διπλο αναστολεα επαναπροσληψης και μεθοδος για την παρασκευη αυτου
EP2813218B1 (en) * 2013-06-14 2022-08-24 Shin-Etsu Chemical Co., Ltd. Method for producing aqueous enteric coating liquid, solid preparation, and method for producing same
CN103393615B (zh) * 2013-07-24 2015-07-15 海南华益泰康药业有限公司 一种度洛西汀肠溶小丸及其制备方法
PL224543B1 (pl) 2013-08-21 2017-01-31 Pabianickie Zakłady Farm Polfa Spółka Akcyjna Dojelitowa tabletka duloksetyny
AU2013404367B2 (en) 2013-10-29 2020-02-27 Tillotts Pharma Ag A delayed release drug formulation
EP3065720A1 (en) 2013-11-04 2016-09-14 Capsugel Belgium NV Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
KR102377103B1 (ko) * 2014-05-20 2022-03-23 뉴트리션 & 바이오사이언시즈 유에스에이 1, 엘엘씨 에스테르화된 셀룰로오스 에테르를 포함하는 캡슐 쉘
CN107072980A (zh) * 2014-08-22 2017-08-18 麦迪帕斯有限公司 在药物递送中使用的用于大麻素包衣的组合物和方法
US10471152B2 (en) * 2014-08-29 2019-11-12 Capsugel Belgium Nv Colloidal dispersion comprising HPMCAS
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
US9668975B2 (en) 2014-10-14 2017-06-06 PharmaDax Inc. Method of preparing drug agglomerate
CN105726488B (zh) * 2014-12-08 2020-10-20 上海爱科百发生物医药技术有限公司 含有呼吸道合胞病毒抑制剂的肠溶微丸及其制备方法
KR101625344B1 (ko) 2015-12-21 2016-06-08 주식회사 유영제약 세레콕시브 및 둘록세틴을 함유하는 약제학적 조성물
CN105534949A (zh) * 2016-01-06 2016-05-04 北京修正创新药物研究院有限公司 一种盐酸度洛西汀的肠溶微丸制剂
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6815109B2 (ja) * 2016-06-23 2021-01-20 キョーリンリメディオ株式会社 デュロキセチンまたは薬学的に許容されるその塩を有効成分とする医薬組成物
JP6856326B2 (ja) * 2016-07-15 2021-04-07 富士化学工業株式会社 腸放出粒子組成物
CN106166144A (zh) * 2016-08-12 2016-11-30 海南合瑞制药股份有限公司 一种盐酸度洛西汀肠溶胶囊药物组合物
JP2018172361A (ja) * 2016-10-14 2018-11-08 大原薬品工業株式会社 光安定性を改善した、デュロキセチンを含有する固形製剤
US9839626B1 (en) * 2016-12-14 2017-12-12 Sun Pharmaceutical Industries Limited Duloxetine sprinkles
JP7072431B2 (ja) * 2017-04-14 2022-05-20 富士化学工業株式会社 錠剤及びその製造方法
JP6972674B2 (ja) * 2017-06-06 2021-11-24 ニプロ株式会社 経口医薬製剤
JP2020029447A (ja) * 2018-06-25 2020-02-27 大原薬品工業株式会社 腸溶性高分子及び抗付着剤を含有する顆粒
CN115844846A (zh) * 2018-10-25 2023-03-28 上海上药中西制药有限公司 盐酸度洛西汀肠溶制剂、其主药层及其混悬液、其隔离层及其包衣液、及其制备方法
JP7050714B2 (ja) * 2019-04-04 2022-04-08 信越化学工業株式会社 腸溶性コーティング用組成物及び固形製剤の製造方法
JP2020189815A (ja) * 2019-05-23 2020-11-26 東和薬品株式会社 デュロキセチン製剤およびその安定化方法
US20220265659A1 (en) 2019-09-02 2022-08-25 Inserm (Institut National De La Santé Et De Al Recherche Médicale) Methods and compositions for treating pax6-deficiency related disease
WO2021126099A1 (en) * 2019-12-18 2021-06-24 Santa Farma İlaç Sanayi̇ A.Ş. An enteric coated pellet comprising duloxetine hydrochloride with optimized degrees of neutralization
WO2021126098A1 (en) * 2019-12-18 2021-06-24 Santa Farma İlaç Sanayi̇ A.Ş. Gastro-resistant pellet comprising duloxetine
WO2022115054A1 (en) * 2020-11-27 2022-06-02 Santa Farma Ilac Sanayii A.S. Enteric coated duloxetine compositions
WO2024117996A1 (en) * 2022-11-30 2024-06-06 Santa Farma Ilac Sanayii A.S. Bioequivalent oral pharmaceutical composition comprising duloxetine hydrochloride

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517116A (en) * 1974-06-11 1976-01-21 Shinetsu Chemical Co Choyoseihifukuyakuzaino seizohoho
CH649216A5 (de) * 1979-08-16 1985-05-15 Sandoz Ag Verfahren zur auftragung eines magensaftresistenten filmes auf einen heilmittelkern und feste einheitsdosierungsform mit magensaftresistentem film.
US5019302A (en) 1986-03-12 1991-05-28 Washington University Technology Associates, Inc. Method for granulation
US5100592A (en) 1986-03-12 1992-03-31 Washington University Technology Associated, Inc. Method and apparatus for granulation and granulated product
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
JPH04346930A (ja) * 1991-05-25 1992-12-02 Sumitomo Pharmaceut Co Ltd 安定なアスピリン腸溶錠
ZA93694B (en) * 1993-02-01 1993-06-03 Lilly Co Eli Pharmaceutical treatments.
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis

Cited By (1)

* Cited by examiner, † Cited by third party
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US8397404B2 (en) 2006-03-07 2013-03-19 Jung Bae Kim Health shoes

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ZA955799B (en) 1997-01-13
NO2005002I2 (no) 2009-10-05
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MY116361A (en) 2004-01-31
PL309588A1 (en) 1996-01-22
IL114584A (en) 1999-09-22
US5508276A (en) 1996-04-16
YU48095A (sh) 1998-07-10
NO312397B1 (no) 2002-05-06
RU2147231C1 (ru) 2000-04-10
DK0693282T3 (da) 2001-05-07
NO952786L (no) 1996-01-19
KR100356240B1 (ko) 2002-12-26
HUT72466A (en) 1996-04-29
YU49445B (sh) 2006-03-03
JP3707831B2 (ja) 2005-10-19
CO4410177A1 (es) 1997-01-09
CZ180595A3 (en) 1996-03-13
GEP20063944B (en) 2006-10-10
DE69520711T2 (de) 2001-09-20
GR3036185T3 (en) 2001-10-31
NO952786D0 (no) 1995-07-13
HU221502B (en) 2002-10-28
CZ288095B6 (cs) 2001-04-11
IL114584A0 (en) 1995-11-27
ES2157297T3 (es) 2001-08-16
TW382596B (en) 2000-02-21
DE69520711D1 (de) 2001-05-23
PE32196A1 (es) 1996-08-07
SI0693282T1 (en) 2002-02-28
HU9502134D0 (en) 1995-09-28
AU2505195A (en) 1996-02-01
CN1106191C (zh) 2003-04-23
JPH0840895A (ja) 1996-02-13
BR9503346A (pt) 1996-02-27
EP0693282A2 (en) 1996-01-24
CN1128141A (zh) 1996-08-07
PL181296B1 (pl) 2001-07-31
NO2005002I1 (no) 2005-02-28
UA41344C2 (uk) 2001-09-17
ATE200620T1 (de) 2001-05-15
EP0693282A3 (en) 1996-12-18
AU686384B2 (en) 1998-02-05
EP0693282B1 (en) 2001-04-18

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