KR950702242A - 사포린 함유 단백질의 재조합 생산방법(Recombinant production of saporin-containing proteins) - Google Patents

사포린 함유 단백질의 재조합 생산방법(Recombinant production of saporin-containing proteins)

Info

Publication number: KR950702242A
Authority: KR; South Korea
Prior art keywords: saporin; recombinant production; containing proteins; proteins; recombinant
Prior art date: 1992-06-16

Application number

KR1019940704654A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-16

Filing date

1994-12-16

Publication date

1995-06-19

1994-12-16 Application filed filed Critical

1995-06-19 Publication of KR950702242A publication Critical patent/KR950702242A/ko

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Botany (AREA)
Toxicology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

KR1019940704654A 1992-06-16 1994-12-16 사포린 함유 단백질의 재조합 생산방법(Recombinant production of saporin-containing proteins) KR950702242A (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90171892A	1992-06-16	1992-06-16
PCT/US1993/005702 WO1993025688A1 (en)	1992-06-16	1993-06-14	Recombinant production of saporin-containing proteins

Publications (1)

Publication Number	Publication Date
KR950702242A true KR950702242A (ko)	1995-06-19

Family

ID=25414703

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019940704654A KR950702242A (ko)	1992-06-16	1994-12-16	사포린 함유 단백질의 재조합 생산방법(Recombinant production of saporin-containing proteins)

Country Status (7)

Country	Link
US (1)	US5916772A (ko)
EP (1)	EP0646174A1 (ko)
JP (1)	JPH07507926A (ko)
KR (1)	KR950702242A (ko)
AU (1)	AU685058B2 (ko)
CA (1)	CA2138038A1 (ko)
WO (1)	WO1993025688A1 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5529932A (en) *	1988-01-28	1996-06-25	Pharmacia, S.P.A.	Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis
WO1996008293A1 (en) *	1992-12-23	1996-03-21	Patrick Edison Kane	Injection molded water-soluble golf ball
JPH09503751A (ja) *	1993-08-02	1997-04-15	プリズムファーマシュティカルズ，インコーポレイティド	細胞毒性抱合体の単一起源性製剤
CA2185671A1 (en) *	1994-03-15	1995-09-21	Prizm Pharmaceuticals, Inc.	Heparin-binding growth factors for gene therapy and anterior eye disorders
US6037329A (en)	1994-03-15	2000-03-14	Selective Genetics, Inc.	Compositions containing nucleic acids and ligands for therapeutic treatment
AU3374795A (en) *	1994-08-29	1996-03-22	Prizm Pharmaceuticals, Inc.	Conjugates of vascular endothelial growth factor with targeted agents
WO1996008274A2 (en) *	1994-09-13	1996-03-21	Prizm Pharmaceuticals, Inc.	Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents
EP0833665A1 (en) *	1995-05-16	1998-04-08	Prizm Pharmaceuticals, Inc.	Compositions containing nucleic acids and ligands for therapeutic treatment
AU3641297A (en) *	1996-06-24	1998-01-14	Prizm Pharmaceuticals, Inc.	Heparinized medical devices containing heparin-binding growth factor conjugates
US20050043234A1 (en) *	1996-10-16	2005-02-24	Deisher Theresa A.	Novel FGF homologs
US7470665B2 (en)	1999-12-02	2008-12-30	Zymogenetics, Inc.	Methods for targeting cells that express fibroblast growth receptor-3 or -2
ES2493840T3 (es) *	2002-10-07	2014-09-12	Zymogenetics, Inc.	Procedimiento de administración de FGF-18
WO2004094613A2 (en) *	2003-04-22	2004-11-04	Ibc Pharmaceuticals	Polyvalent protein complex
JP5130662B2 (ja) *	2006-06-07	2013-01-30	Ｊｎｃ株式会社	タンパク質の可溶性タンパク質としての製造方法
EP2280063A1 (en) *	2009-07-28	2011-02-02	Consiglio Nazionale delle Ricerche	Pichia pastoris as a host for the production of the ribosome-inactivating protein (RIP) saporin and saporin fusion chimaeras
EP4490298A1 (en) *	2022-03-09	2025-01-15	Ospedale San Raffaele S.r.l.	Fusion proteins and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4468382A (en) *	1982-07-15	1984-08-28	New England Medical Center, Inc.	Polypeptide-toxin hybrid protein
EP0170697B1 (en) *	1984-02-08	1991-10-23	Cetus Oncology Corporation	Toxin conjugates
US4785079A (en) *	1984-11-09	1988-11-15	The Salk Institute For Biological Studies	Isolation of fibroblast growth factor
US5155214A (en) *	1984-03-05	1992-10-13	The Salk Institute For Biological Studies	Basic fibroblast growth factor
US4962188A (en) *	1985-12-06	1990-10-09	Cetus Corporation	Recombinant ricin toxin A chain conjugates
IN165717B (ko) *	1986-08-07	1989-12-23	Battelle Memorial Institute
GB8801877D0 (en) *	1988-01-28	1988-02-24	Erba Carlo Spa	Nucleotide sequence encoding plant ribosome inactivating protein
DE68921918T2 (de) *	1988-05-09	1995-09-07	Univ Temple	Verfahren zur Voraussage der Wirksamkeit einer antineoplastichen Behandlung bei einzelnen Patienten.
US5169933A (en) *	1988-08-15	1992-12-08	Neorx Corporation	Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
US5175147A (en) *	1988-08-19	1992-12-29	Takeda Chemical Industries, Ltd	Acid-resistant fgf composition and method of treating ulcerating diseases of the gastrointestinal tract
US5120715A (en) *	1988-12-12	1992-06-09	Takeda Chemical Industries, Ltd.	Method for purifying fibroblast growth factor protein
GB9001466D0 (en) *	1990-01-23	1990-03-21	Erba Carlo Spa	Extracellular form of the human fibroblast growth factor receptor
US5191067A (en) *	1989-04-27	1993-03-02	The Salk Institute For Biological Studies	Fibroblast growth factor conjugates
US5458878A (en) *	1990-01-02	1995-10-17	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	P. exotoxin fusio proteins have COOHG220101al alterations which increase cytotoxicity
US5248606A (en) *	1990-06-11	1993-09-28	Dowelanco	Dna encoding inactive precursor and active forms of maize ribosome inactivating protein
WO1992004918A1 (en) *	1990-09-19	1992-04-02	The Salk Institute For Biological Studies	Treatment of tumorigenic pathophysiological conditions with fgf-cytotoxic conjugates
US5116753A (en) *	1991-07-30	1992-05-26	The Salk Institute For Biological Studies	Maintenance of pancreatic islets
AU4532593A (en) *	1992-06-15	1994-01-04	Whittier Institute For Diabetes And Endocrinology, The	Cytotoxins specific for gm-csf receptor-bearing cells

1993
- 1993-06-14 JP JP6501784A patent/JPH07507926A/ja active Pending
- 1993-06-14 EP EP93916536A patent/EP0646174A1/en not_active Ceased
- 1993-06-14 WO PCT/US1993/005702 patent/WO1993025688A1/en not_active Application Discontinuation
- 1993-06-14 AU AU46353/93A patent/AU685058B2/en not_active Ceased
- 1993-06-14 CA CA002138038A patent/CA2138038A1/en not_active Abandoned
- 1993-06-14 US US08/356,161 patent/US5916772A/en not_active Expired - Fee Related
1994
- 1994-12-16 KR KR1019940704654A patent/KR950702242A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1993025688A1 (en)	1993-12-23
JPH07507926A (ja)	1995-09-07
US5916772A (en)	1999-06-29
AU685058B2 (en)	1998-01-15
EP0646174A1 (en)	1995-04-05
CA2138038A1 (en)	1993-12-23
AU4635393A (en)	1994-01-04

Publication	Publication Date	Title
DE69434520D1 (de)	2005-12-01	Biotinylierung von proteinen
KR100386762B1 (ko)	2005-12-09	재조합사람혈청알부민의제조방법
ATA257190A (de)	1995-07-15	Virales polypeptid
DK603888D0 (da)	1988-10-28	Rekombinant virus
KR950702242A (ko)	1995-06-19	사포린 함유 단백질의 재조합 생산방법(Recombinant production of saporin-containing proteins)
FI952574L (fi)	1995-05-26	Glykosyylitransferaasiaktiiviset proteiinit
DK132892D0 (da)	1992-10-30	Proteiner
DK353788D0 (da)	1988-06-27	Polypeptidderivater
DK354389D0 (da)	1989-07-18	Polypeptid
FI941749L (fi)	1994-05-25	Rekombinantti-Borrelia -proteiinien valmistus
DK0406598T3 (da)	1994-07-04	Proteinhydrolyse
DE68925304D1 (de)	1996-02-15	Minimale Derivatisierung von Proteinen
DK395288D0 (da)	1988-07-15	Proteiner
KR950701894A (ko)	1995-05-17	하이드로 플루오로 알칸 제조 방법(production of hydrofluoroalkanes)
DE69030414D1 (de)	1997-05-15	Reinigung von Albumin
DE69120700D1 (de)	1996-08-14	Polypeptidepaar
NO944025L (no)	1994-10-21	Forbedret fremstilling av rekombinant protein
FI951633L (fi)	1995-04-05	Erittyvien proteiinien lisääntynyt tuotanto eukaryoottisilla yhdistelmäsoluilla
DK75393D0 (da)	1993-06-24	Production of protein
DK354989D0 (da)	1989-07-18	Modificerede proteiner
GB9104596D0 (en)	1991-04-17	Production of recombinant proteins
FI942467A0 (fi)	1994-05-26	Proteesivakaat proteiinit
DK82592D0 (da)	1992-06-23	Fremstilling af proteiner
ITRM920517A0 (it)	1992-07-08	Procedimento di produzione della proteina sv-iv ricombinante e proteina sv-iv ricombinante.
DK596888D0 (da)	1988-10-27	Rekombinant lymfotoksin

Legal Events

Date	Code	Title	Description
1994-12-16	PA0105	International application	Patent event date: 19941216 Patent event code: PA01051R01D Comment text: International Patent Application
1995-06-19	PG1501	Laying open of application
1998-06-13	A201	Request for examination
1998-06-13	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 19980613 Comment text: Request for Examination of Application
2000-05-25	E902	Notification of reason for refusal
2000-05-25	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 20000525 Patent event code: PE09021S01D
2001-02-02	E601	Decision to refuse application
2001-02-02	PE0601	Decision on rejection of patent	Patent event date: 20010202 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20000525 Comment text: Notification of reason for refusal Patent event code: PE06011S01I