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KR950700876A - 비타민 D 동족체(Vitamin D analogues) - Google Patents

비타민 D 동족체(Vitamin D analogues)

Info

Publication number
KR950700876A
KR950700876A KR1019940703687A KR19940703687A KR950700876A KR 950700876 A KR950700876 A KR 950700876A KR 1019940703687 A KR1019940703687 A KR 1019940703687A KR 19940703687 A KR19940703687 A KR 19940703687A KR 950700876 A KR950700876 A KR 950700876A
Authority
KR
South Korea
Prior art keywords
pct
deuterium
sec
hydrogen
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019940703687A
Other languages
English (en)
Other versions
KR100285146B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR950700876A publication Critical patent/KR950700876A/ko
Application granted granted Critical
Publication of KR100285146B1 publication Critical patent/KR100285146B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019940703687A 1992-07-03 1993-06-07 비타민 d 동족체 및 이의 제조방법 Expired - Fee Related KR100285146B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929214202A GB9214202D0 (en) 1992-07-03 1992-07-03 Chemical compounds
GB9214202.5 1992-07-03
PCT/DK1993/000196 WO1994001398A1 (en) 1992-07-03 1993-06-07 Vitamin d analogues

Publications (2)

Publication Number Publication Date
KR950700876A true KR950700876A (ko) 1995-02-20
KR100285146B1 KR100285146B1 (ko) 2001-04-02

Family

ID=10718182

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703687A Expired - Fee Related KR100285146B1 (ko) 1992-07-03 1993-06-07 비타민 d 동족체 및 이의 제조방법

Country Status (17)

Country Link
US (1) US5545633A (ko)
EP (1) EP0648207B1 (ko)
JP (1) JPH08504746A (ko)
KR (1) KR100285146B1 (ko)
AT (1) ATE150013T1 (ko)
AU (1) AU667378B2 (ko)
CA (1) CA2131631A1 (ko)
DE (1) DE69308852T2 (ko)
DK (1) DK0648207T3 (ko)
ES (1) ES2101319T3 (ko)
FI (1) FI106120B (ko)
GB (1) GB9214202D0 (ko)
GR (1) GR3023407T3 (ko)
HU (1) HU222775B1 (ko)
NZ (1) NZ253026A (ko)
RU (1) RU2114825C1 (ko)
WO (1) WO1994001398A1 (ko)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226860D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Novel treatment
DE4427690A1 (de) * 1994-08-04 1996-02-08 Bogdahn Ulrich Prof Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum
ES2130522T3 (es) * 1994-12-14 1999-07-01 Duphar Int Res Compuestos de vitamina d y metodo para preparar estos compuestos.
TW422696B (en) 1995-03-20 2001-02-21 Katsuhiko Mukai Ophthalmic composition containing active vitamin D
GB9526208D0 (en) * 1995-12-21 1996-02-21 Res Inst Medicine Chem Chemical compounds
GB9721156D0 (en) * 1997-10-06 1997-12-03 Leo Pharm Prod Ltd Novel vitamin d analogues
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
SI1436321T1 (sl) * 2001-10-19 2006-12-31 Isotechnika Inc Sinteza analogov ciklosporina
US8404667B2 (en) * 2006-12-29 2013-03-26 Wisconsin Alumni Research Foundation Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
MX2007006262A (es) * 2004-11-22 2007-07-10 Wisconsin Alumni Res Found 2-metilen-19-nor-1a-hidroxi-17-en homopregnacalciferol y sus usos.
US8193169B2 (en) * 2006-04-06 2012-06-05 Wisconsin Alumni Research Foundation (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs
US8222236B2 (en) 2008-07-10 2012-07-17 Wisconsin Alumni Research Foundation 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs
US7879829B2 (en) * 2008-07-10 2011-02-01 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2-dihydrofuran ring
US7713953B2 (en) * 2008-07-10 2010-05-11 Wisconsin Alumni Research Foundation 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs
US7648974B1 (en) * 2008-07-10 2010-01-19 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 3,2-dihydrofuran ring
US7888339B2 (en) * 2008-07-10 2011-02-15 Wisconsin Alumni Research Foundation 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs
US8193170B2 (en) * 2008-07-10 2012-06-05 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs
US8399439B2 (en) 2008-07-10 2013-03-19 Wisconsin Alumni Research Foundation 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs
US7893043B2 (en) * 2008-07-10 2011-02-22 Wisconsin Alumni Research Foundation 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs
EP2312944B1 (en) * 2008-07-15 2018-09-05 Theracos, Inc. Deuterated benzylbenzene derivatives and methods of use
EA201691980A1 (ru) 2009-01-27 2017-07-31 БЕРГ ЭлЭлСи Способы уменьшения побочных эффектов, связанных с химиотерапией
KR101880032B1 (ko) 2009-08-14 2018-07-20 베르그 엘엘씨 탈모증 치료용 비타민 ｄ3 및 이의 유사체들
US8217023B2 (en) 2009-10-02 2012-07-10 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2- or 3,2-cyclopentene ring
WO2011041579A2 (en) 2009-10-02 2011-04-07 Wisconsin Alumni Research Foundation (20S,22E)-2-METHYLENE-19-NOR-22-ENE-1α,25-DIHYDROXYVITAMIN D3 ANALOGS
US9834512B2 (en) 2011-06-03 2017-12-05 Wisconsin Alumni Research Foundation (22E)-2-methylene-26,27-cyclo-22-dehydro-1α-hydroxy-19-norvitamin D3 derivatives
WO2013003307A1 (en) 2011-06-28 2013-01-03 Wisconsin Alumni Research Foundation 2-methylene-(22e)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin d analogs
US20130178449A1 (en) 2011-07-18 2013-07-11 Wisconsin Alumni Research Foundation 2-Methylene-20(21)-Dehydro-19,24,25,26,27-Pentanor-Vitamin D Analogs
US9416102B2 (en) 2013-01-23 2016-08-16 Wisconsin Alumni Research Foundation (22E)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 analogs
CA2913543C (en) 2013-05-29 2024-01-09 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
DK3223808T3 (en) 2014-11-25 2019-03-25 Trophea Dev Ab TREATMENT OF HUDATROPHY WITH A COMBINATION OF TRIIODTHYROEDIC ACID (TRIAC) AND DEHYDROEPIANDROSTERON (DHEA)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i

Also Published As

Publication number Publication date
GR3023407T3 (en) 1997-08-29
HU9402484D0 (en) 1994-11-28
US5545633A (en) 1996-08-13
ES2101319T3 (es) 1997-07-01
KR100285146B1 (ko) 2001-04-02
DK0648207T3 (da) 1997-06-23
RU94046411A (ru) 1996-10-10
EP0648207B1 (en) 1997-03-12
GB9214202D0 (en) 1992-08-12
HU222775B1 (hu) 2003-10-28
AU667378B2 (en) 1996-03-21
RU2114825C1 (ru) 1998-07-10
HUT68025A (en) 1995-05-29
FI950023L (fi) 1995-01-02
CA2131631A1 (en) 1994-01-20
DE69308852D1 (de) 1997-04-17
WO1994001398A1 (en) 1994-01-20
DE69308852T2 (de) 1997-11-27
EP0648207A1 (en) 1995-04-19
AU4311193A (en) 1994-01-31
FI106120B (fi) 2000-11-30
ATE150013T1 (de) 1997-03-15
JPH08504746A (ja) 1996-05-21
NZ253026A (en) 1997-07-27
FI950023A0 (fi) 1995-01-02

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19941018

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19980605

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20000523

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20001010

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20001229

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20001230

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

Termination category: Default of registration fee

Termination date: 20040910