KR950013513A - 약제 제조용 모에노마이신 및 이의 유도체, 및 모에노마이신 또는 이의 유도체를 함유하는 약제 - Google Patents
약제 제조용 모에노마이신 및 이의 유도체, 및 모에노마이신 또는 이의 유도체를 함유하는 약제 Download PDFInfo
- Publication number
- KR950013513A KR950013513A KR1019940031633A KR19940031633A KR950013513A KR 950013513 A KR950013513 A KR 950013513A KR 1019940031633 A KR1019940031633 A KR 1019940031633A KR 19940031633 A KR19940031633 A KR 19940031633A KR 950013513 A KR950013513 A KR 950013513A
- Authority
- KR
- South Korea
- Prior art keywords
- derivatives
- moenomycin
- medicament
- manufacture
- gastric ulcer
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract 9
- PERZMHJGZKHNGU-JGYWJTCASA-N bambermycin Chemical compound O([C@H]1[C@H](NC(C)=O)[C@@H](O)[C@@H]([C@H](O1)CO[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@@H]1O[C@@H]([C@H]([C@H](O)[C@H]1NC(C)=O)O[C@H]1[C@@H]([C@@H](O)[C@@H](O)[C@H](O1)C(=O)NC=1C(CCC=1O)=O)O)C)[C@H]1[C@@H](OP(O)(=O)OC[C@@H](OC\C=C(/C)CC\C=C\C(C)(C)CCC(=C)C\C=C(/C)CCC=C(C)C)C(O)=O)O[C@H](C(O)=O)[C@@](C)(O)[C@@H]1OC(N)=O PERZMHJGZKHNGU-JGYWJTCASA-N 0.000 title claims abstract 7
- 238000004519 manufacturing process Methods 0.000 title claims 4
- 208000007107 Stomach Ulcer Diseases 0.000 claims abstract 6
- 201000005917 gastric ulcer Diseases 0.000 claims 5
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 229940088710 antibiotic agent Drugs 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 206010019375 Helicobacter infections Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008177 pharmaceutical agent Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Abstract
본 발명은 약제 제조용 모에노마이신 및 이의 유도체 및 모에노마이신 또는 이의 유도체를 함유하는 약제에 관한 것이다. 모에노마이신 및 이의 유도체는 위궤양의 치료 및 헬리코박터 필로리 감염증 치료용 약제 제조에 적합하다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (6)
- 위궤양의 치료 및 위암을 예방하기 위한 약제를 제조하기 위한 모에노마이신 및/또는 하나 이상의 이의 유도체의 용도.
- 헬리코박터 필로리 감염증 치료용 약제를 제조하기 위한 모에노마이신 및/또는 하나 이상의 이의 유도체의 용도.
- 모에노마이신 및/또는 하나 이상의 이의 유도체 이외에 추가로 하나 이상의 위궤양 치료제 및/또는 항생제를 함유하는 약제.
- 모에노마이신 및/또는 하나 이상의 이의 유도체를 하나 이상의 추가의 위궤양 치료제 및, 또는 항생제와 함께 및, 경우에 따라, 약리학적으로 허용되는 보조제 및/또는 부형제를 사용하여 적합한 투여형태로 제조함을 포함하여 제 3항에서 청구한 약제를 제조하는 방법.
- 위궤양의 치료 및/또는 위암의 예방을 위한 제 3항에서 청구한 약제의 용도.
- 제 3항에서 청구한 약제를 투여함을 포함하여 위궤양을 치료하는 방법※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4340774A DE4340774A1 (de) | 1993-11-30 | 1993-11-30 | Moenomycin und dessen Derivate zur Herstellung von Arzneimitteln, sowie Arzneimittel mit einem Gehalt an Moenomycin oder dessen Derivaten |
DEP4340774.9 | 1993-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR950013513A true KR950013513A (ko) | 1995-06-15 |
Family
ID=6503798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940031633A KR950013513A (ko) | 1993-11-30 | 1994-11-29 | 약제 제조용 모에노마이신 및 이의 유도체, 및 모에노마이신 또는 이의 유도체를 함유하는 약제 |
Country Status (18)
Country | Link |
---|---|
US (1) | US6242424B1 (ko) |
EP (1) | EP0655249B1 (ko) |
JP (1) | JPH07188030A (ko) |
KR (1) | KR950013513A (ko) |
CN (1) | CN1108104A (ko) |
AT (1) | ATE199497T1 (ko) |
AU (1) | AU693482B2 (ko) |
BR (1) | BR9404781A (ko) |
CA (1) | CA2136936A1 (ko) |
DE (2) | DE4340774A1 (ko) |
DK (1) | DK0655249T3 (ko) |
ES (1) | ES2154665T3 (ko) |
GR (1) | GR3035928T3 (ko) |
IL (1) | IL111780A0 (ko) |
NO (1) | NO944575L (ko) |
NZ (1) | NZ270002A (ko) |
PT (1) | PT655249E (ko) |
ZA (1) | ZA949468B (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19709897A1 (de) * | 1997-03-11 | 1998-09-17 | Hoechst Ag | Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel |
US6114309A (en) | 1997-11-21 | 2000-09-05 | Incara Research Laboratories | Combinatorial library of moenomycin analogs and methods of producing same |
EP1069130B1 (en) * | 1999-07-15 | 2004-08-11 | Hoechst Marion Roussel | Moenomycin A Derivatives, their preparation, and use as antibacterial products |
US6585846B1 (en) | 2000-11-22 | 2003-07-01 | 3M Innovative Properties Company | Rotary converting apparatus and method for laminated products and packaging |
WO2008021367A2 (en) * | 2006-08-11 | 2008-02-21 | President And Fellows Of Harvard College | Moenomycin biosynthesis-related compositions and methods of use thereof |
WO2009046314A2 (en) * | 2007-10-04 | 2009-04-09 | President And Fellows Of Harvard College | Moenomycin analogs, methods of synthesis, and uses thereof |
US8916540B2 (en) * | 2008-01-15 | 2014-12-23 | Academia Sinica | Antibiotic compositions and related screening methods |
US20100309510A1 (en) * | 2009-06-09 | 2010-12-09 | Accipiter Innovations, Llc | Systems, methods and devices for printing from a mobile device |
EP2850090B1 (en) | 2012-04-06 | 2018-10-03 | President and Fellows of Harvard College | Chemoenzymatic methods for synthesizing moenomycin analogs |
WO2013151697A1 (en) | 2012-04-06 | 2013-10-10 | President And Fellows Of Harvard College | Methods and compounds for identifying glycosyltransferase inhibitors |
WO2013152277A2 (en) | 2012-04-06 | 2013-10-10 | President And Fellows Of Harvard College | Moenomycin analogs, methods of synthesis, and uses thereof |
US11883421B2 (en) * | 2017-05-05 | 2024-01-30 | Huvepharma | Functionalized saccharides as anti-inflammatory agents |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0130327B1 (de) * | 1983-05-21 | 1987-11-04 | Hoechst Aktiengesellschaft | Moenomycin A-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Antibiotika |
-
1993
- 1993-11-30 DE DE4340774A patent/DE4340774A1/de not_active Withdrawn
-
1994
- 1994-11-23 AT AT94118415T patent/ATE199497T1/de not_active IP Right Cessation
- 1994-11-23 DE DE59409670T patent/DE59409670D1/de not_active Expired - Fee Related
- 1994-11-23 EP EP94118415A patent/EP0655249B1/de not_active Expired - Lifetime
- 1994-11-23 PT PT94118415T patent/PT655249E/pt unknown
- 1994-11-23 DK DK94118415T patent/DK0655249T3/da active
- 1994-11-23 ES ES94118415T patent/ES2154665T3/es not_active Expired - Lifetime
- 1994-11-28 US US08/348,815 patent/US6242424B1/en not_active Expired - Fee Related
- 1994-11-28 AU AU79086/94A patent/AU693482B2/en not_active Ceased
- 1994-11-28 NZ NZ270002A patent/NZ270002A/en unknown
- 1994-11-28 IL IL11178094A patent/IL111780A0/xx unknown
- 1994-11-28 CN CN94118973A patent/CN1108104A/zh active Pending
- 1994-11-29 JP JP6294091A patent/JPH07188030A/ja not_active Abandoned
- 1994-11-29 KR KR1019940031633A patent/KR950013513A/ko not_active Application Discontinuation
- 1994-11-29 CA CA002136936A patent/CA2136936A1/en not_active Abandoned
- 1994-11-29 BR BR9404781A patent/BR9404781A/pt not_active Application Discontinuation
- 1994-11-29 NO NO944575A patent/NO944575L/no unknown
- 1994-11-29 ZA ZA949468A patent/ZA949468B/xx unknown
-
2001
- 2001-05-25 GR GR20010400781T patent/GR3035928T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL111780A0 (en) | 1995-01-24 |
GR3035928T3 (en) | 2001-08-31 |
NO944575L (no) | 1995-05-31 |
JPH07188030A (ja) | 1995-07-25 |
AU693482B2 (en) | 1998-07-02 |
NO944575D0 (no) | 1994-11-29 |
CA2136936A1 (en) | 1995-05-31 |
EP0655249B1 (de) | 2001-03-07 |
ATE199497T1 (de) | 2001-03-15 |
DE4340774A1 (de) | 1995-06-01 |
BR9404781A (pt) | 1995-08-01 |
EP0655249A1 (de) | 1995-05-31 |
CN1108104A (zh) | 1995-09-13 |
ZA949468B (en) | 1995-08-01 |
DK0655249T3 (da) | 2001-06-18 |
NZ270002A (en) | 1997-05-26 |
DE59409670D1 (de) | 2001-04-12 |
ES2154665T3 (es) | 2001-04-16 |
AU7908694A (en) | 1995-06-08 |
US6242424B1 (en) | 2001-06-05 |
PT655249E (pt) | 2001-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19941129 |
|
PG1501 | Laying open of application | ||
PC1203 | Withdrawal of no request for examination | ||
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |