[go: up one dir, main page]

KR940014279A - 아이오드화 습윤제 - Google Patents

아이오드화 습윤제 Download PDF

Info

Publication number
KR940014279A
KR940014279A KR1019930022701A KR930022701A KR940014279A KR 940014279 A KR940014279 A KR 940014279A KR 1019930022701 A KR1019930022701 A KR 1019930022701A KR 930022701 A KR930022701 A KR 930022701A KR 940014279 A KR940014279 A KR 940014279A
Authority
KR
South Korea
Prior art keywords
acid
compound
triiodophenyl
acetylamino
win
Prior art date
Application number
KR1019930022701A
Other languages
English (en)
Inventor
알.베이컨 에드워드
엘. 매킨타이어 그레고리
Original Assignee
폴 이. 듀퐁
스터얼링 윈드롭 아이엔씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 폴 이. 듀퐁, 스터얼링 윈드롭 아이엔씨 filed Critical 폴 이. 듀퐁
Publication of KR940014279A publication Critical patent/KR940014279A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

본원은 X-선 이미징 조성물내 습윤제로서 특히 유용한 하기구조식 화합물.
(Z)-COO는 아이오드화 방향족산의 잔기, M은 H, 흑종의 양이온, -(CH2CH2O)mH 및 -(CH2CH2(OH)O)-pH, m은 1-150의 정수 ; p는 1-50의 정수 ; 및 L은 알킬렌, 싸이클로 알킬렌, 아릴렌, 아릴렌알킬렌, 및 알킬렌아릴렌에서 선택된 한개이상의 2가 연결기에 관한다.

Description

아이오드화 습윤제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 하기구조식의 화합물.
    (Z)-COO는 아이오드화 방향족산의 잔기, M은 H, 흑종의 양이온, -(CH2CH2O)mH 및 -(CH2CH2(OH)O)-pH, m은 1-150의 정수 ; p는 1-50의 정수 ; 및 L은 알킬렌, 싸이클로 알킬렌, 아릴렌, 아릴렌알킬렌, 및 알킬렌아릴렌에서 선택된 한개이상의 2가 연결기
  2. 제 1 항에 있어서, (Z)-COO가 디아트리조산, 메트리조산, 우로콘산, 아이오탈란산, 트리메스산, 아이옥사갈산, 아이옥시 탈람산, 테트라아이오도테레프탈산 및 아이오디프아미드에서 선택된 아이오드화 방향족산의 잔기인 화합물.
  3. 제 1 항에 있어서, (Z)-COO가 디아트리조산잔기인 화합물.
  4. 제 1 항에 있어서 5-[3´, 5´비스(아세틸아미노)-2´, 4´, 6´-트리아이오도페닐)카보닐옥시]펜타노산(WIN 68040), 6-[3´, 5´비스(아세틸아미노)-2´, 4´, 6´-트리아이오도페닐)카보닐옥시]헥사노산(WIN 68056), 7-[3´, 5´비스(아세틸아미노)-2´, 4´, 6´-트리아이오도페닐)카보닐옥시]헵타노산(WIN 68167), 8-[3´, 5´비스(아세틸아미노)-2´, 4´, 6´-트리아이오도페닐)카보닐옥시]옥타노산(WIN 68237 및 4-[3´, 5´비스(아세틸아미노)-2´, 4´, 6´-트리아이오도페닐)카보닐옥시메틸]벤노산(WIN 68016)으로 구성되는 그룹에서 선택되는 화합물.
  5. 재 1 항에 있어서, Z이 식중 n은 1,2 또는 3, 각각의 R은 독립하여 H, C1-C8알킬, 또는 C1-C18플루오로알킬, 및 R1과 R2는 독립하여 H 또는 C1-C18알킬임인 화합물.
  6. 제 1 항의 화합물로 구성되는 X-선 조영조성물.
  7. 제 6 항에 있어서 제약학적으로 허용되는 담체를 추가로 함유하는 X-선 조영조성물.
  8. 포유류의 신체에 조영유효량(contrast effective amount)의 제 6 항의 조영조성물을 투여하는 것으로 구성되는 의료용 X-선 진단 이미징방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930022701A 1992-12-16 1993-10-29 아이오드화 습윤제 KR940014279A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/991,640 US5346688A (en) 1992-12-16 1992-12-16 Iodinated wetting agents
US92-07/991,640 1992-12-16

Publications (1)

Publication Number Publication Date
KR940014279A true KR940014279A (ko) 1994-07-18

Family

ID=25537417

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930022701A KR940014279A (ko) 1992-12-16 1993-10-29 아이오드화 습윤제

Country Status (16)

Country Link
US (1) US5346688A (ko)
EP (1) EP0603917A1 (ko)
JP (1) JPH06211764A (ko)
KR (1) KR940014279A (ko)
AU (1) AU671143B2 (ko)
CA (1) CA2108061A1 (ko)
CZ (1) CZ235493A3 (ko)
FI (1) FI935376L (ko)
HU (1) HUT65743A (ko)
IL (1) IL107130A (ko)
MX (1) MX9306011A (ko)
MY (1) MY109446A (ko)
NO (1) NO933506L (ko)
NZ (1) NZ248702A (ko)
PH (1) PH30680A (ko)
SK (1) SK120693A3 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters
US5488133A (en) * 1994-03-10 1996-01-30 Eastman Kodak Company Iodinated aroyloxy ketones
US5573750A (en) * 1995-05-22 1996-11-12 Nanosystems L.L.C. Diagnostic imaging x-ray contrast agents
JP2005519657A (ja) * 2001-11-07 2005-07-07 インコール ファーマシューティカル カンパニー ナノ微粒子造影剤を用いた血管撮像の方法
WO2003082213A2 (en) * 2002-03-28 2003-10-09 Imcor Pharmaceutical Company Compositions and methods for delivering pharmaceutically active agents using nanoparticulates
EP2679624A1 (en) * 2012-06-29 2014-01-01 URSA Insulation, S.A. Formaldehyde-free binder and use for mineral wool insulation products
CN117986193A (zh) * 2022-11-01 2024-05-07 科睿驰（深圳）医疗科技发展有限公司 显影化合物及其制备方法、显影栓塞材料及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL239757A (ko) * 1958-06-03
US3144479A (en) * 1958-08-07 1964-08-11 Chemie Linz Ag New iodine-containing benzoic acid esters
DE1082368B (de) * 1958-08-11 1960-05-25 Lentia Gmbh Roentgenkontrastmittel
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters

Also Published As

Publication number Publication date
IL107130A (en) 1997-04-15
NO933506D0 (no) 1993-09-30
FI935376A0 (fi) 1993-12-01
FI935376L (fi) 1994-06-17
JPH06211764A (ja) 1994-08-02
MY109446A (en) 1997-01-31
NO933506L (no) 1994-06-17
IL107130A0 (en) 1993-12-28
MX9306011A (es) 1994-06-30
AU4747093A (en) 1994-06-30
NZ248702A (en) 1995-12-21
CA2108061A1 (en) 1994-06-17
AU671143B2 (en) 1996-08-15
HU9303602D0 (en) 1994-04-28
CZ235493A3 (en) 1994-07-13
US5346688A (en) 1994-09-13
HUT65743A (en) 1994-07-28
PH30680A (en) 1997-09-16
SK120693A3 (en) 1994-07-06
EP0603917A1 (en) 1994-06-29

Similar Documents

Publication Publication Date Title
KR940014293A (ko) 아이오드화 아로일옥시 에스테르
KR960702447A (ko) 간담용 자기공명 콘트라스트제(hepatobiliary magnetic resonance contrast agents)
EE03350B1 (et) Jodeeritud röntgenkontrastaine
ES2091323T3 (es) Medios de contraste.
SE7610922L (sv) Ljusskyddsmedel for kosmetiska endamal
KR900016192A (ko) 도파민 수용체 리간드 및 영상화제
ES2039220T3 (es) Procedimiento para preparar complejos de cis-platino.
KR940014279A (ko) 아이오드화 습윤제
KR910700320A (ko) 불소화 올리고페닐을 함유한 액정 매질
KR940014287A (ko) 아이오드화 벤조일 아세탈 및 케탈
KR890012936A (ko) 저칼로리 지질유사물
KR920701869A (ko) 포지티브 레지스트 조성물
KR890008589A (ko) 액정 조성물
KR900013056A (ko) 액정 폴리에스테르 수지 조성물
KR920006480A (ko) 활성 매트릭스에 적용하기 위한 네마틱 액정 조성물
KR940005707A (ko) 폴리에스테르 화합물 및 이를 함유하는 유기 겔화제
FI102745B (fi) Uusia jodattuja ei-ionisia trijodibentseeniyhdisteitä ja niitä sisältä viä varjoaineita
KR900006285A (ko) 소염성 3-아실-2-옥신돌-1-카복사미드의 전구약제
KR920013028A (ko) 광증감제 조성물
KR920019735A (ko) 산 분해성 감조사선성 화합물, 이를 함유하는 감조사선성 혼합물 및 당해 혼합물로 제조한 감조사선성 기록물질
KR900013853A (ko) 어망용 오염방지제
KR850001663A (ko) 살충 및 응애류 박멸제 조성물
KR920019732A (ko) 산-분해성 감조사선성 화합물, 이를 함유하는 감조사선성 혼합물 및 당해 혼합물로 제조한 감조사선성 기록물질
KR910004620A (ko) 위궤양 치료제
KR880010778A (ko) 뇌의 순환 및 신진대사 개선제

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19931029

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 19960722

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid