KR930006148A - 신균주 슈도모나스속 y-132 및 이로부터 생산되는 글루타릴-7-아미노세팔로스포린산 아실라아제 - Google Patents
신균주 슈도모나스속 y-132 및 이로부터 생산되는 글루타릴-7-아미노세팔로스포린산 아실라아제 Download PDFInfo
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- KR930006148A KR930006148A KR1019910015753A KR910015753A KR930006148A KR 930006148 A KR930006148 A KR 930006148A KR 1019910015753 A KR1019910015753 A KR 1019910015753A KR 910015753 A KR910015753 A KR 910015753A KR 930006148 A KR930006148 A KR 930006148A
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- South Korea
- Prior art keywords
- glutaryl
- aminocephalosporin
- acylase
- pseudomonas
- new strain
- Prior art date
Links
- 241000589516 Pseudomonas Species 0.000 title claims abstract 6
- 238000004519 manufacturing process Methods 0.000 claims abstract description 5
- 229940099596 manganese sulfate Drugs 0.000 claims abstract description 3
- 235000007079 manganese sulphate Nutrition 0.000 claims abstract description 3
- 239000011702 manganese sulphate Substances 0.000 claims abstract description 3
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims abstract description 3
- UVZICZIVKIMRNE-UHFFFAOYSA-N thiodiacetic acid Chemical compound OC(=O)CSCC(O)=O UVZICZIVKIMRNE-UHFFFAOYSA-N 0.000 claims abstract description 3
- 235000015097 nutrients Nutrition 0.000 claims abstract 2
- 241000507753 Acila Species 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 abstract description 4
- 108090000790 Enzymes Proteins 0.000 abstract description 4
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- ACXMTAJLYQCRGF-PBFPGSCMSA-N cefatrizine Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)[C@H](N)C=2C=CC(O)=CC=2)CC=1CSC1=CN=N[N]1 ACXMTAJLYQCRGF-PBFPGSCMSA-N 0.000 abstract 1
- 229960002420 cefatrizine Drugs 0.000 abstract 1
- 229960004682 cefoperazone Drugs 0.000 abstract 1
- GCFBRXLSHGKWDP-XCGNWRKASA-N cefoperazone Chemical compound O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC(O)=CC=1)C(=O)N[C@@H]1C(=O)N2C(C(O)=O)=C(CSC=3N(N=NN=3)C)CS[C@@H]21 GCFBRXLSHGKWDP-XCGNWRKASA-N 0.000 abstract 1
- 229960004261 cefotaxime Drugs 0.000 abstract 1
- GPRBEKHLDVQUJE-VINNURBNSA-N cefotaxime Chemical compound N([C@@H]1C(N2C(=C(COC(C)=O)CS[C@@H]21)C(O)=O)=O)C(=O)/C(=N/OC)C1=CSC(N)=N1 GPRBEKHLDVQUJE-VINNURBNSA-N 0.000 abstract 1
- 238000011534 incubation Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Description
Claims (3)
- 글루타릴-7-아미노세팔로스포린산 아실라아제를 생산하는 신균주 슈도모나스속 Y-132(기탁번호: KCTC 0014 BP).
- 슈도모나스속 Y-132(기탁번호: KCTC 0014 BP)를 황산망간 0.015%, 티오디글리콜린산 0.1%를 함유하는 영양배지에서 배양하고, 그 균체로부터 글루타릴-7-아미노세팔로스포린산 아실라아제를 회수함을 특징으로 하는 글루타릴-7-아미노세팔로스포린산 아실라아제의 제조방법.
- 슈도모나스속 Y-132(기탁번호: KCTC 0014 BP)로부터 생산되고, 분자량이 약 56,000달톤이며, 등전점이 5.9인 것을 특징으로 하는 글루타릴-7-아미노세팔로스포린산 아실라아제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019910015753A KR930008972B1 (ko) | 1991-09-10 | 1991-09-10 | 신균주 슈도모나스속 y-132 및 이로부터 생산되는 글루타릴-7-아미노세팔로스포린산 아실라아제 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019910015753A KR930008972B1 (ko) | 1991-09-10 | 1991-09-10 | 신균주 슈도모나스속 y-132 및 이로부터 생산되는 글루타릴-7-아미노세팔로스포린산 아실라아제 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR930006148A true KR930006148A (ko) | 1993-04-20 |
| KR930008972B1 KR930008972B1 (ko) | 1993-09-17 |
Family
ID=19319767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019910015753A KR930008972B1 (ko) | 1991-09-10 | 1991-09-10 | 신균주 슈도모나스속 y-132 및 이로부터 생산되는 글루타릴-7-아미노세팔로스포린산 아실라아제 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR930008972B1 (ko) |
-
1991
- 1991-09-10 KR KR1019910015753A patent/KR930008972B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR930008972B1 (ko) | 1993-09-17 |
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