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KR930004265A - 신규 치환 n-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법 - Google Patents

신규 치환 n-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법 Download PDF

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KR930004265A
KR930004265A KR1019920013830A KR920013830A KR930004265A KR 930004265 A KR930004265 A KR 930004265A KR 1019920013830 A KR1019920013830 A KR 1019920013830A KR 920013830 A KR920013830 A KR 920013830A KR 930004265 A KR930004265 A KR 930004265A
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alkyl
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hydrogen atom
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KR100231610B1 (ko
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데루오 우메모또
긴지로 도미자와
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야마다 미노루
다이낑고오교 가부시끼가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

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Abstract

내용 없음.

Description

신규 치환 N-플루오로피리디늄술포네이트, 그의 중간체 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 하기 식(Ⅰ)의 치환 N-플루오로피리디늄 술포네이트.
    [상기 식중, R1은 수소원자, 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이고, R2은 C1~C4알킬 또는 할로알킬기이다].
  2. 제1항의 치환 N-플루오로피리디늄술포네이트로 구성된 플루오르화제.
  3. 하기 식(Ⅱ)의 이치환 피리딘-2-술폰산 또는 그의 염.
    [상기 식중, R2은 C1~C4알킬 또는 할로알킬이고, R3은 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이다].
  4. 하기 식(Ⅲ)의 할로알킬-치환 피리딘-2-술폰산 또는 그의 염.
    [상기 식중, R4은 C1~C4할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이다].
  5. 하기 식(Ⅳ)의 알킬-치환 피리딘-2-술폰산 또는 그의 염.
    상기 식중, R5은 에틸기 또는 t-부틸기이고, M은 수소원자, 금속원소 또는 암모늄기이다].
  6. 하기 식(Ⅴ)의 치환 피리딘 술폰산을 하기 식(Ⅵ)의 아민 화합물의 존재하에 분자상 불소와 반응시킴을 특징으로 하는 제1항의 치환 N-플루오로피리디늄술포네이트(Ⅰ)의 제조방법.
    [상기 식중, R1은 수소원자, 할로겐원자 또는 C1~C4알킬 또는 할로알킬기이고, R2은 C1~C4알킬 또는 할로알킬기이며, R6,R7및 R8은 동일하거나 상이하며 각각은 수소원자 또는 C1~C8알킬 또는 아랄킬기이다].
  7. 하기 식(ⅩⅠ)의 치환 2-할로피리딘을 아황산염과 반응시키고 임의로 생성 화합물을 산으로 처리함을 특징으로 하는 하기 식(Ⅹ)의 치환 피리딘-2-술폰산 또는 그의 염의 제조방법.
    [상기 식중, R4은 C1~C4할로알킬기이고, R9은 수소원자, 할로겐원자 또는 C1~C4할로알킬기이며, M은 수소원자, 금속원소 또는 암모늄기이고, X은 할로겐원자이다].
  8. 제2항의 플루오르화제를 사용하여 화합물을 플루오르화하는 방법.
  9. 제8항에 있어서, 화합물이 유기 화합물인 방법.
  10. 제9항에 있어서, 유기 화합물이 친핵성 화합물인 방법.
    ※참고사항:최초출원 내용에 의하여 공개하는 것임.
KR1019920013830A 1991-08-01 1992-07-31 신규치환n-플루오로피리디늄술포네이트,그의중간체및그의제조방법 Expired - Fee Related KR100231610B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP91-192981 1991-08-01
JP19298191 1991-08-01
JP92-34854 1992-02-21
JP3485492 1992-02-21

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KR930004265A true KR930004265A (ko) 1993-03-22
KR100231610B1 KR100231610B1 (ko) 1999-11-15

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KR1019920013830A Expired - Fee Related KR100231610B1 (ko) 1991-08-01 1992-07-31 신규치환n-플루오로피리디늄술포네이트,그의중간체및그의제조방법

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US (1) US5374732A (ko)
EP (1) EP0526849B1 (ko)
JP (1) JP3094677B2 (ko)
KR (1) KR100231610B1 (ko)
CA (1) CA2074991A1 (ko)
DE (1) DE69230358T2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0559660U (ja) * 1991-12-28 1993-08-06 京セラ株式会社 光ディスク
KR100292736B1 (ko) * 1994-10-22 2001-06-15 이노우에 노리유끼 공액형 엔-플루오로피리디늄염 함유 중합체 및 그의 용도
JP4045601B2 (ja) * 1995-08-03 2008-02-13 ダイキン工業株式会社 Ｎ，ｎ’−ジフルオロジアゾニアビシクロアルカン塩の製造方法、その合成中間体ならびに目的生成物およびその目的生成物の応用
DE102004059916A1 (de) 2004-12-13 2006-06-14 Robert Bosch Gmbh Disc-Monopol-Antennenstruktur
US9130267B2 (en) 2007-03-30 2015-09-08 Fractus, S.A. Wireless device including a multiband antenna system
TWI753910B (zh) 2016-05-16 2022-02-01 美商拜歐斯瑞克斯公司 吡啶硫酮、其醫藥組合物及其治療增生性、炎性、神經退化性或免疫介導疾病之治療用途

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652574A (en) * 1984-11-14 1987-03-24 Nippon Kayaku Kabushiki Kaisha Certain mono-, di- or tri-substituted pyridyl esters of alkane sulfonic acids having insecticidal, acaricidal and nematocidal properties
US5081249A (en) * 1985-06-03 1992-01-14 Sagami Chemical Research Center N-fluoropyridinium-Sulfonates and a process for their preparation
CA1288777C (en) * 1985-06-03 1991-09-10 Teruo Umemoto N-fluoropyridinium salt and process for preparing same
JPH0233707A (ja) * 1988-07-22 1990-02-02 Hitachi Ltd フロッピディスク装置の制御方式および磁気記録媒体
JPH0819103B2 (ja) * 1989-04-18 1996-02-28 財団法人相模中央化学研究所 ２―ハロピリジン―６―スルホン酸及びその塩
US4935519A (en) * 1989-05-12 1990-06-19 Allied-Signal Inc. N-fluoropyridinium pyridine heptafluorodiborate
JPH0819105B2 (ja) * 1989-09-12 1996-02-28 財団法人相模中央化学研究所 Ｎ―フルオロピリジニウム―スルホナート

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CA2074991A1 (en) 1993-02-02
DE69230358D1 (de) 2000-01-05
KR100231610B1 (ko) 1999-11-15
JP3094677B2 (ja) 2000-10-03
EP0526849B1 (en) 1999-12-01
EP0526849A1 (en) 1993-02-10
US5374732A (en) 1994-12-20
JPH05294937A (ja) 1993-11-09
DE69230358T2 (de) 2000-05-11

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